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  1. Review

    Obesity: systemic and pulmonary complications, biochemical abnormalities, and impairment of lung function

    Obesity is currently one of the major epidemics of this millennium and affects individuals throughout the world. It causes multiple systemic complications, some of which result in severe impairment of organs a...

    Thiago Thomaz Mafort, Rogério Rufino, Cláudia Henrique Costa and Agnaldo José Lopes

    Multidisciplinary Respiratory Medicine 2016 11:28

    Published on: 12 July 2016

  2. Original research article

    Most Italians attending a congress on health of elderly people do not know and do not recognize respiratory diseases

    The present study reports the results of a survey jointly carried out by three Italian respiratory scientific associations (AIMAR, AIPO, SIMeR) together with an important Federation of elderly patients (FederA...

    Nicola Ciancio, Claudio M. Sanguinetti, Franco Falcone, Claudio Taranto, Roberto Fasani, Fernando De Benedetto, Onofrio Resta, Fausto De Michele, Roberto Messina, Andrea Rossi, Stefano Nardini and Giuseppe Di Maria

    Multidisciplinary Respiratory Medicine 2016 11:26

    Published on: 5 July 2016

  3. Original research article

    High bacterial load of indoor air in hospital wards: the case of University of Gondar teaching hospital, Northwest Ethiopia

    The air inhaled by people is abundantly populated with microorganisms which also are called bioaerosols. Bioaerosols is a colloidal suspension, formed by liquid droplets and particles of solid matter in the ai...

    Zemichael Gizaw, Mulat Gebrehiwot and Chalachew Yenew

    Multidisciplinary Respiratory Medicine 2016 11:24

    Published on: 5 July 2016

  4. Case report

    Sarcoidosis with prevalent and severe joint localization: a case report

    Sarcoidosis is a systemic granulomatous disease of unknown origin, characterized by the formation of granulomas without central necrosis. Each organ and tissue can be affected by the disease, but in most cases...

    Livio G. Moccia, Sabrina Castaldo, Emanuela Sirignano, Maddalena Napolitano, Enrica Barra and Alessandro Sanduzzi

    Multidisciplinary Respiratory Medicine 2016 11:27

    Published on: 29 June 2016

  5. Original research article

    Evaluation of the rapid immunochromatographic ODK0501 assay for Streptococcus pneumoniae antigen detection with nasopharyngeal swabs: preliminary report

    Early identification and control of pathogenic bacteria are important in the treatment of pneumonia. Currently, two rapid antigen detection kits for pneumococcal pneumonia are available: one uses urine samples...

    Shoji Suzuki, Naoki Nishimura, Torahiko Jinta, Yasuhiko Yamano, Genta Ishikawa, Yutaka Tomishima, Noboru Uchiyama and Naohiko Chohnabayashi

    Multidisciplinary Respiratory Medicine 2016 11:25

    Published on: 20 June 2016

  6. Original research article

    Prospective study of the efficacy of antibiotics versus antitussive drugs for the management of URTI-related acute cough in children

    Acute cough is one of the most frequent symptoms prompting a visit to a health care provider, usually following a viral upper respiratory tract infection (URTI). The disproportionate use of antibiotics in chil...

    Alessandro Zanasi, Luigi Lanata, Federico Saibene, Giovanni Fontana, Peter V. Dicpinigaitis, Valentina Venier and Francesco De Blasio

    Multidisciplinary Respiratory Medicine 2016 11:29

    Published on: 13 June 2016

  7. Original research article

    Fluticasone furoate/Vilanterol 92/22 μg once-a-day vs Beclomethasone dipropionate/ Formoterol 100/6 μg b.i.d.: a 12-week cost analysis in mild-to-moderate asthma

    Asthma is a disease with high cost for the National Health Service. Two of the most recent LABA/ICS combinations for persistent bronchial asthma are Beclomethasone dipropionate/Formoterol (B/F) delivered via t...

    Roberto W. Dal Negro, Chiara Distante, Luca Bonadiman, Paola Turco and Sergio Iannazzo

    Multidisciplinary Respiratory Medicine 2016 11:20

    Published on: 6 June 2016

  8. Original research article

    Acid–base balance, serum electrolytes and need for non-invasive ventilation in patients with hypercapnic acute exacerbation of chronic obstructive pulmonary disease admitted to an internal medicine ward

    Hypoventilation produces or worsens respiratory acidosis in patients with hypercapnia due to acute exacerbations of chronic obstructive pulmonary disease (AECOPD). In these patients acid–base and hydroelectrol...

    Alfonso Schiavo, Maurizio Renis, Mario Polverino, Arcangelo Iannuzzi and Francesca Polverino

    Multidisciplinary Respiratory Medicine 2016 11:23

    Published on: 25 May 2016

  9. Original research article

    Effectiveness, safety and tolerability of a complex homeopathic medicinal product in the prevention of recurrent acute upper respiratory tract infections in children: a multicenter, open, comparative, randomized, controlled clinical trial

    The present study was initiated to investigate the effectiveness, safety and tolerability of complex homeopathic CalSuli-4-02 tablets on prevention of recurrent acute upper respiratory tract infections (URTIs)...

    Miek C. Jong, Stephen L. Buskin, Lydia Ilyenko, Irina Kholodova, Julia Burkart, Stephan Weber, Thomas Keller and Petra Klement

    Multidisciplinary Respiratory Medicine 2016 11:19

    Published on: 16 May 2016

  10. Original research article

    Prevalence of pulmonary tuberculosis in young adult patients with Type 1 diabetes mellitus in India

    There is limited information on prevalence of pulmonary tuberculosis (PTB) in patients with type-1-diabetes. We assessed the prevalence of PTB in patients with type-1-diabetes attending the outpatient-clinic i...

    Abilash Nair, Randeep Guleria, Devasenathipathy Kandasamy, Raju Sharma, Nikhil Tandon, Urvashi B. Singh and Ravinder Goswami

    Multidisciplinary Respiratory Medicine 2016 11:22

    Published on: 10 May 2016

  11. Review

    Mometasone furoate nasal spray: a systematic review

    The inflammatory diseases of the nose, rhino-pharynx and paranasal sinuses (allergic and non allergic rhinitis, NARES; rhinosinusitis with/without nasal polyposis, adenoidal hypertrophy with/without middle ear...

    Desiderio Passali, Maria Carla Spinosi, Anna Crisanti and Luisa Maria Bellussi

    Multidisciplinary Respiratory Medicine 2016 11:18

    Published on: 2 May 2016

  12. Original research article

    Placement of self-expandable bifurcated metallic stents without use of fluoroscopic and guidewire guidance to palliate central airway lesions

    Self-expandable metallic stents (SEMS) can be used to treat malignant obstructions and fistulas of the central airways. SEMS can be placed using different methods. Recently, a rigid bronchoscope has been used ...

    Cengiz Özdemir, Sinem Nedime Sökücü, Levent Karasulu, Seda Tural Önür and Levent Dalar

    Multidisciplinary Respiratory Medicine 2016 11:15

    Published on: 30 April 2016

  13. Case report

    Tracheobronchopathia Osteochondroplastica: a rare case report of a non-smoker and non-atopic patient, with a long history of wheezing since childhood

    Tracheobronchopathia Osteochondroplastica (TBPO) is an uncommon and benign condition characterized by osseous or metaplastic cartilaginous 1–3 mm nodules in the submucosa of the tracheo-bronchial tree. Posteri...

    Alessandro G. Fois, Antonella Arcadu, Luigi Santoru, Rocco Trisolini, Vincenzo Marras, Giorgio C. Ginesu, Sara Canu, Lorenzo Cordero, Gabriella Diana and Pietro Pirina

    Multidisciplinary Respiratory Medicine 2016 11:16

    Published on: 19 April 2016

  14. Original research article

    Increased expression of A Proliferation-inducing Ligand (APRIL) in lung leukocytes and alveolar epithelial cells in COPD patients with non small cell lung cancer: a possible link between COPD and lung cancer?

    Chronic Obstructive Pulmonary Disease (COPD) is characterized by an excessive activation of the adaptive immune system and, in particular, uncontrolled expansion of the B-cell pool. One of the key promoters of...

    Francesca Polverino, Maria Laucho-Contreras, Joselyn Rojas Quintero, Miguel Divo, Victor Pinto-Plata, Lynette Sholl, Juan P. de-Torres, Bartolome R. Celli and Caroline A. Owen

    Multidisciplinary Respiratory Medicine 2016 11:17

    Published on: 4 April 2016

  15. Original research article

    Chronic respiratory symptoms and associated factors among cement factory workers in Dejen town, Amhara regional state, Ethiopia, 2015

    Chronic respiratory diseases represent a public health challenge in both industrialized and developing countries. Chronic respiratory symptoms are more prevalent in cement factories of developing countries, wh...

    Zemichael Gizaw, Bamlaku Yifred and Takele Tadesse

    Multidisciplinary Respiratory Medicine 2016 11:13

    Published on: 1 March 2016

  16. Original research article

    Differentiation of respiratory epithelium in a 3-dimensional co-culture with fibroblasts embedded in fibrin gel

    Tracheal tissue engineering is a promising option for the treatment of tracheal defects. In a previous study we proved the suitability of fibrin gel as a scaffold for tracheal tissue engineering. This study in...

    Stefanie Albers, Anja Lena Thiebes, Kai L. Gessenich, Stefan Jockenhoevel and Christian G. Cornelissen

    Multidisciplinary Respiratory Medicine 2016 11:6

    Published on: 1 March 2016

  17. Review

    Health-related quality of life measurement in asthma and chronic obstructive pulmonary disease: review of the 2009-2014 literature

    Asthma and chronic obstructive pulmonary disease (COPD) are frequent in the general population. These diseases can worsen the quality of life of people suffering from them, limiting their daily activities and ...

    Fabio Arpinelli, Mauro Carone, Gioacchino Riccardo and Giorgio Bertolotti

    Multidisciplinary Respiratory Medicine 2016 11:5

    Published on: 15 February 2016

  18. Reviewer acknowledgement

    Reviewer acknowledgement 2015

    The editors of Multidisciplinary Respiratory Medicine would like to thank all of our reviewers who have contributed to the journal in Volume 10 (2015).

    Fernando De Benedetto, Claudio F. Donner and Claudio M. Sanguinetti

    Multidisciplinary Respiratory Medicine 2016 11:9

    Published on: 11 February 2016

  19. Review

    N-acetylcysteine in COPD: why, how, and when?

    Oxidants have long been recognized to have an important role in the pathogenesis of COPD, and in this cigarette smoke has a strong responsibility, because it generates a conspicuous amount of oxidant radicals ...

    Claudio M. Sanguinetti

    Multidisciplinary Respiratory Medicine 2016 11:8

    Published on: 3 February 2016

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