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Table 1 Histopathological score for single parameters and total score.

From: Anti-inflammatory effects of montelukast on smoke-induced lung injury in ratsEffetto antinfiammatorio del montelukast sul danno polmonare indotto da fumo nel ratto

   

Groups

  

Histopathological categories

Grade range

Healthy control

MON group

MON control

COPD control

Dilatation of respiratory tract

0-3

0.7 ± 0.2

1.7 ± 0.2

2.3 ± 0.3

2.3 ± 0.3

Infiltration of inflammatory cells

0-3

0.6 ± 0.2

1.3 ± 0.2

2.9 ± 0.1

2.9 ± 0.1

Proliferation of respiratory epithelium

0-3

0.9 ± 0.1

1.4 ± 0.2

2.6 ± 0.2

2.7 ± 0.2

Vascular congestion

0-1

0.1 ± 0.1

0.7 ± 0.2

0.7 ± 0.2

0.9 ± 0.1

Total histopathological score

0-10

2.3 ± 0.2**

5.1 ± 0.6*

8.4 ± 0.6

8.7 ± 0.4

  1. * p < 0.05; MON group vs. MON control and COPD control groups.
  2. ** p < 0.001; healthy control vs. MON control and COPD control groups.
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Multidisciplinary Respiratory Medicine

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