Table 4 Comparison of patients according to 6MWD (above vs. below 204 meters)
Variables | Groups according to 6MWD 204 meter median (quartiles 25% to 75%) | P | |
|---|---|---|---|
204 m and lower, n = 8 | 205 m and higher, n = 17 | ||
Gender, male/female | 3/5 | 14/3 | 0.025 |
Age, year | 55 (52 to 65) | 46 (42 to 53) | 0.013 |
Body mass index, kg/m2 | 32 (32 to 34) | 27 (20 to 29) | 0.000 |
FEV1, L | 0.76 (0.58 to 0.98) | 0.70 (0.59 to 0.77) | 0.447 |
FEV1,% pred | 35.0 (29.5 to 49.5) | 25.0 (22.0 to 32.0) | 0.006 |
FVC, L | 0.90 (0.69 to 1.23) | 0.82 (0.78 to 0.97) | 0.562 |
FVC, % pred | 33.5 (26.5 to 53.5) | 26.0 (24.0 to 29.0) | 0.038 |
FEV1/FVC, % | 83.0 (76.0 to 92.0) | 84.0 (77.0 to 90.0) | 0.856 |
PaO2/FiO2, mm Hg | 289 (243 to 319) | 279 (258 to 316) | 0.816 |
pH | 7.39 (7.37 to 7.40) | 7.41 (7.38 to 7.43) | 0.218 |
PaCO2, mm Hg | 49.1 (42.8 to 58.4) | 51.0 (48.3 to 57.7) | 0.382 |
HCO3, mmol/L | 27.7 (26.8 to 32.0) | 30.2 (28.8 to 34.2) | 0.165 |
SaO2,% | 91.8 (85.0 to 93.6) | 90.3 (88.6 to 93.7) | 0.907 |
6MWD, meter | 190 (180 to 197) | 300 (270 to 351) | 0.000 |
6MWD, % predicted | 35.1 (30.5 to 42.2) | 45.9 (43.3 to 52.7) | 0.003 |
Pulse heart rate/min, baseline | 82 (74 to 88) | 88 (83 to 100) | 0.210 |
Pulse heart rate/min, end of test | 124 (108 to 136) | 123 (117 to 132) | 0.610 |
SpO2%, baseline | 94 (92 to 96) | 92 (92 to 95) | 0.220 |
SpO2%, end of test | 88 (73 to 93) | 73 (70 to 82) | 0.061 |
Fatigue score, baseline | 0 (0 to 2) | 0 (0 to 0) | 0.068 |
Fatigue score, end of test | 6 (3 to 7) | 3 (0 to 4) | 0.005 |
Dyspnea score, baseline | 1 (0 to 2) | 0 (0 to 0) | 0.026 |
Dyspnea score, end of test | 7 (6 to 8) | 4 (2 to 5) | 0.012 |