Table 1 Prognostic factors revealed by univariate and multivariate analyses in patients with completely resected non-small cell carcinoma of the lung (N = 98).
Number of patients (n = 98) | 5-year survival rate (%) | Univariate analysis p | Multivariate analysis p HR (95% CI) | |
|---|---|---|---|---|
Sex | 0.19 | |||
Female | 9 (10%) | 44% | ||
Male | 89 (90%) | 68% | ||
Tumor size | 0.48 | |||
< 20 mm | 10 (10%) | 81% | ||
21-30 mm | 13 (13%) | 66% | ||
31-50 mm | 46 (47%) | 55% | ||
> 50 mm | 29 (30%) | 53% | ||
Tumor localization | 0.98 | |||
Left | 33 (34%) | 65% | ||
Right | 65 (66%) | 67% | ||
T classification | 0.49 | |||
T1 | 23 (23%) | 76% | ||
T2 | 76 (77%) | 63% | ||
N classification | 0.018 | 0.01 | ||
N0 | 57(58%) | 76% | 2.3 (1.15-4.8) | |
N1 | 41(42%) | 49% | ||
Histology | 0.013 | 0.03 | ||
Squamous cell | 53 (54%) | 79% | 2.2 (1.05-4.6) | |
Adenocarcinoma | 40 (40%) | 49% | ||
Others | 5 (6%) | 60% | ||
Tumor differentiation | 0.81 | |||
Poor | 45 (46%) | 62% | ||
Moderate | 39 (40%) | 67% | ||
Well | 14 (14%) | 69% | ||
Surgical procedure | 0.80 | |||
Lobectomy | 72 (73%) | 69% | ||
Pneumonectomy | 26 (27%) | 66% | ||
Perineural invasion | 0.4 | |||
Positive | 25 (26%) | 63% | ||
Negative | 73 (74%) | 71% | ||
Blood vessel invasion | 0.068 | 0.75 | ||
Positive | 55 (56%) | 57% | 1.14 (0.4-2.7) | |
Negative | 43 (44%) | 75% | ||
Lymphatic vessel invasion | 0.82 | |||
Positive | 79 (80%) | 66% | ||
Negative | 19 (20%) | 62% | ||
EGFR expression | 0.13 | 0.23 | ||
Positive | 51 (52%) | 57% | 1.6 (0.7-3.6) | |
Negative | 47 (48%) | 73% |