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Table 1 Synopsis of the literature on collateral effects of radiotherapy

From: Cryptogenic organizing pneumonia after radiotherapy for breast cancerPolmonite organizzativa criptogeneticadopo radioterapia per cancro della mammella

Lung Pneumonia 1-3 months (acute) 12-15 months (late) 30 Gy Mosvas et al. Chest 1997;111:1061
  Necrosis 12 months (1-7 years for cavitations) > 60 Gy   
  Pneumothorax 16 months > 30 Gy Penniment et al. Thorax 1994;49:936
Breast COP 6 wk to 10 months no minimal dose defined Crestani et al. ERJ 1995;8:318
Lymph nodes Calcifications 12 months no minimal dose defined Bereton et al. Radiology 1974;112:705
Esophagus Stricture 3-18 months 60 Gy Lepke et al. Radiology 1993;148:375
Vascular tree Stenosis or occlusion 10-15 years Aorta and pulm. artery 24-44 Gy Subclavian 40-60 Gy Fajardo et al. Pathol Ann 1988;23:297
Heart Coronary artery disease 10-15 years > 30 Gy age < 20 Kopelson et al. Int J Radiat Oncol Biol Phys 1978;4:895
  Pericarditis 12-48 months 40 Gy Applefeld et al. Ann Intern Med1981;94:338
  Conduction abnormalities 10 years 40 Gy Cohen et al. Arch Intern Med1981;141:676
Chest wall Sarcoma > 5 years no minimal dose defined Libshitz Semin Roent 1994;29:15
  Rib fractures > 12 years 50 Gy Pierce et al. Int J Radiat Oncol Biol Phys 1992;23:915
  Breast carcinoma 15-19 years > 20 Gy age < 35 Bhatia et al. NEJM 1996;334:745