Table 1 Synopsis of the literature on collateral effects of radiotherapy
Lung | Pneumonia | 1-3 months (acute) 12-15 months (late) | 30 Gy | Mosvas et al. | Chest 1997;111:1061 |
|---|---|---|---|---|---|
Necrosis | 12 months (1-7 years for cavitations) | > 60 Gy | |||
Pneumothorax | 16 months | > 30 Gy | Penniment et al. | Thorax 1994;49:936 | |
Breast | COP | 6 wk to 10 months | no minimal dose defined | Crestani et al. | ERJ 1995;8:318 |
Lymph nodes | Calcifications | 12 months | no minimal dose defined | Bereton et al. | Radiology 1974;112:705 |
Esophagus | Stricture | 3-18 months | 60 Gy | Lepke et al. | Radiology 1993;148:375 |
Vascular tree | Stenosis or occlusion | 10-15 years | Aorta and pulm. artery 24-44 Gy Subclavian 40-60 Gy | Fajardo et al. | Pathol Ann 1988;23:297 |
Heart | Coronary artery disease | 10-15 years | > 30 Gy age < 20 | Kopelson et al. | Int J Radiat Oncol Biol Phys 1978;4:895 |
Pericarditis | 12-48 months | 40 Gy | Applefeld et al. | Ann Intern Med1981;94:338 | |
Conduction abnormalities | 10 years | 40 Gy | Cohen et al. | Arch Intern Med1981;141:676 | |
Chest wall | Sarcoma | > 5 years | no minimal dose defined | Libshitz | Semin Roent 1994;29:15 |
Rib fractures | > 12 years | 50 Gy | Pierce et al. | Int J Radiat Oncol Biol Phys 1992;23:915 | |
Breast carcinoma | 15-19 years | > 20 Gy age < 35 | Bhatia et al. | NEJM 1996;334:745 |