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Table 1 Confirmed and suspected factors leading to increased systolic pulmonary arterial pressure in end stage renal disease (ESRD)

From: Kidney pulmonary hypertension: another road on the map?Ipertensione reno-polmonare: un’altra meta sulla via?

Factors of PH in ESRD

Consequences

High flow arteriovenous fistula

High cardiac output

Endothelium dysfunction

↓NO; ↑TXB; ↑ET-1

Left heart dysfunction

↑pulmonary wedge pressure

Hormonal disturbances

Hyperparathyroidism

Abnormal gas exchange

Hypoxia, pulmonary vasoconstriction

  1. Definition of abbreviations: ET, endothelin; PH, pulmonary hypertension; TXB, thromboxane.
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Multidisciplinary Respiratory Medicine

ISSN: 2049-6958

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