From: BMI can influence adult males’ and females’ airway hyperresponsiveness differently
All AHR subjectsa | Mild AHRa | Moderate AHRa | Severe AHRa | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | P | OR | 95% CI | p | |
Aged 27–44 years b | 0.775 | 0.569-1.057 | 0.107 | 0.899 | 0.600-1.346 | 0.604 | 0.753 | 0.506-1.121 | 0.163 | 0.611 | 0.398-0.939 | 0.025 |
Age ≥ 45 years b | 0.589 | 0.423-0.819 | 0.002 | 0.766 | 0.496-1.181 | 0.227 | 0.558 | 0.364-0.854 | 0.007 | 0.406 | 0.253-0.651 | 0.0001 |
Smoking c | 1.609 | 1.243-2.081 | 0.0001 | 1.414 | 1.014-1.973 | 0.041 | 1.750 | 1.278-2.397 | 0.0001 | 1.767 | 1.229-2.540 | 0.002 |
FEV 1 % of predicted | 0.925 | 0.912-0.939 | 0.0001 | 0.957 | 0.938-0.976 | 0.0001 | 0.928 | 0.910-0.946 | 0.0001 | 0.873 | 0.853-0.894 | 0.0001 |
FVC % of predicted | 1.055 | 1.039-1.070 | 0.0001 | 1.029 | 1.009-1.049 | 0.003 | 1.061 | 1.041-1.080 | 0.0001 | 1.085 | 1.062-1.109 | 0.0001 |
Winter d | 0.645 | 0.491-0.847 | 0.002 | 0.613 | 0.431-0.872 | 0.007 | 0.674 | 0.478-0.950 | 0.024 | 0.662 | 0.447-0.981 | 0.040 |
Spring d | 0.717 | 0.541-0.949 | 0.020 | 0.585 | 0.403-0.849 | 0.005 | 0.810 | 0.572-1.147 | 0.235 | 0.829 | 0.557-1.236 | 0.358 |
Summer d | 0.624 | 0.469-0.830 | 0.001 | 0.681 | 0.476-0.976 | 0.036 | 0.662 | 0.462-0.949 | 0.025 | 0.524 | 0.340-0.807 | 0.003 |
Underweight ef | 1.012 | 0.568-1.805 | 0.967 | 1.222 | 0.611-2.443 | 0.571 | 0.774 | 0.340-1.766 | 0.543 | 0.895 | 0.390-2.055 | 0.793 |
Overweight ef | 1.178 | 0.919-1.509 | 0.195 | 1.042 | 0.752-1.444 | 0.805 | 1.297 | 0.947-1.777 | 0.104 | 1.338 | 0.929-1.928 | 0.118 |
Obese ef | 1.247 | 0.937-1.661 | 0.130 | 0.856 | 0.578-1.268 | 0.439 | 1.741 | 1.226-2.471 | 0.002 | 1.235 | 0.806-1.894 | 0.333 |