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Table 6 Logistic binary regression model to evaluate the risk of the various considered covariates in females with different levels of airways hyperresponsiveness (compared to normal subjects)

From: BMI can influence adult males’ and females’ airway hyperresponsiveness differently

 

All AHR subjectsa

Mild AHRa

Moderate AHRa

Severe AHRa

 

OR

95% CI

p

OR

95% CI

p

OR

95% CI

P

OR

95% CI

p

Aged 27–44 years b

0.775

0.569-1.057

0.107

0.899

0.600-1.346

0.604

0.753

0.506-1.121

0.163

0.611

0.398-0.939

0.025

Age ≥ 45 years b

0.589

0.423-0.819

0.002

0.766

0.496-1.181

0.227

0.558

0.364-0.854

0.007

0.406

0.253-0.651

0.0001

Smoking c

1.609

1.243-2.081

0.0001

1.414

1.014-1.973

0.041

1.750

1.278-2.397

0.0001

1.767

1.229-2.540

0.002

FEV 1 % of predicted

0.925

0.912-0.939

0.0001

0.957

0.938-0.976

0.0001

0.928

0.910-0.946

0.0001

0.873

0.853-0.894

0.0001

FVC % of predicted

1.055

1.039-1.070

0.0001

1.029

1.009-1.049

0.003

1.061

1.041-1.080

0.0001

1.085

1.062-1.109

0.0001

Winter d

0.645

0.491-0.847

0.002

0.613

0.431-0.872

0.007

0.674

0.478-0.950

0.024

0.662

0.447-0.981

0.040

Spring d

0.717

0.541-0.949

0.020

0.585

0.403-0.849

0.005

0.810

0.572-1.147

0.235

0.829

0.557-1.236

0.358

Summer d

0.624

0.469-0.830

0.001

0.681

0.476-0.976

0.036

0.662

0.462-0.949

0.025

0.524

0.340-0.807

0.003

Underweight ef

1.012

0.568-1.805

0.967

1.222

0.611-2.443

0.571

0.774

0.340-1.766

0.543

0.895

0.390-2.055

0.793

Overweight ef

1.178

0.919-1.509

0.195

1.042

0.752-1.444

0.805

1.297

0.947-1.777

0.104

1.338

0.929-1.928

0.118

Obese ef

1.247

0.937-1.661

0.130

0.856

0.578-1.268

0.439

1.741

1.226-2.471

0.002

1.235

0.806-1.894

0.333

  1. Subjects with AHR = PD20 < 3200 μg; Severe AHR = PD20 ≤ 200 μg; moderate AHR = PD20 > 200 and ≤ 800 μg; mild AHR = PD20 > 800 μg; avs subjects with normal reactivity (without PD20); bvs age ≤ 26 years; cvs non-smoking; dvs Autumn; evs normal weight subjects; fadjusted for age, smoking, FEV1, FVC and seasons.