Skip to main content
Figure 1 | Multidisciplinary Respiratory Medicine

Figure 1

From: Prevention of respiratory tract infections with bacterial lysate OM-85 bronchomunal in children and adults: a state of the art

Figure 1

Five stages undergone by OM-85 from its intake to the generation of antibodies in the respiratory mucosae. OM-85, as opposite to typical vaccines that are parenterally administered, is administered orally -the paediatric capsule containing 3.5 mg of lyophilzed extract and the adults’ 7 mg. In the intestine lyophilised bacteria reach Peyer’ patches (1). In this reactive lypmphoid tissue, dendritic cells are primed thereby activating lymphocytes and T and B cells, the latter of which will produce antibodies (2). The immune cells are then transported with the lymph into the mesenteric lymph nodes to mature (3). The activated immune cells reach the mucosa of the respiratory tract (4) and stimulate the innate and adaptive immune system as well as the production of secretory IgA antibodies in the respiratory mucosa (5).

Back to article page