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Table 1 Demographic characteristics and respiratory function test results of the study population

From: Value of serum and induced sputum surfactant protein-D in chronic obstructive pulmonary disease

  Group 1 (control subjects) Group 2 (stage 1 and 2 COPD patients) Group 3 (stage 3 and 4 COPD patients) P
  (n = 20) (n = 20) (n = 20)  
Mean Age (year) 44.85 ± 5.80 60.35 ± 9.40 63.70 ± 8.60 p = 0.001
Gender (F/M) 8/12 0/20 3/17 p = 0.004
Mean BMI (kg/m 2 ) 33.36 ± 5.70 32.8 ± 6.70 29.6 ± 5.90 p = 0.148
Smoking status
Active smokers 16 (80%) 10 (50%) 2 (10%) p = 0.001
Ex-smokers 4 (20%) 10 (50%) 18 (90%)
Cigarette pack years 23 ± 13 (20) 51 ± 28 (45) 51 ± 33(45) p = 0.001
Inhaled steroid use 0 6 18 p = 0.001
Mean FVC (%) 131.5 ± 15.1 101.7 ± 19 76.7 ± 16.8 p = 0.001
Mean FEV 1 (%) 123 ± 14 75.7 ± 16.4 39.7 ± 7.24 p = 0.001
Mean FEV 1 /FVC (%) 78.9 ± 4.8 59.75 ± 10.8 43.3 ± 11.3 p = 0.001
Mean FEF 25-75 (%) 94.5 ± 23.4 33.5 ± 18.6 12.5 ± 4.54 p = 0.001
Mean VC (%) 130 ± 16.9 94.5 ± 19 80.8 ± 19 p = 0.001
Mean RV (%) 120 ± 29 156 ± 37 150 ± 77 p = 0.001
Mean SpO2 (%) 96.6 ± 1.1 94 ± 1.9 92.1 ± 2.1 p = 0.001
Mean CRP level (mg/L) 2.52 ± 2.4 8.3 ± 10 8.1 ± 9.49 p = 0.014
Mean Hb (g/dl) 14.21 ± 1.55 14.7 ± 1.43 14.6 ± 14 p = 0.282
Mean WBC (/μL) 7.449 ± 1.704 7.291 ± 1.084 8.402 ± 1.694 p = 0.102
Mean PMNL (/μL) 4.272 ± 1.166 4.310 ± 956 5.519 ± 1.205 p = 0.003
  1. The results are expressed as mean ± standard deviation.
  2. BMI Body mass index, CRP C-reactive protein, FEV 1 forced expiratory volume, FRC functional residual capacity, FVC forced vital capacity, Hb hemoglobin, PMNL polymorphonucleer leukocyte, RV residual volume, TLC total lung capacity, VC vital capacity, WBC white blood cell count.