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Table 1 Comparison between general characteristics of patients with asthma and with COPD

From: Predictors of cardiovascular disease in asthma and chronic obstructive pulmonary disease

 

ASTHMA N. 100

COPD N. 129

P

Age, years

59 ± 1.1

69 ± 0.9

< 0.0001

BMI

25.6 ± 0.5

26.2 ± 0.45

0.010

Male, n (%)

22 (22.0)

78 (60.5)

< 0.0001

Smokers

   

  current, n (%)

10 (10)

72 (55.8)

< 0.0001

  past, n (%)

8 (8)

42 (32.6)

< 0.0001

Atopy,n (%)

65 (73.1)

10 (7.7)

< 0.0001

Cardiovascular disease, n (%)

68 (68)

117 (90.7)

0.00002

  Pressure overload, n (%)

38 (38.0)

59 (45.7)

NS

  Volume overload, n (%)

30 (30.0)

58 (45.0)

0.021

  Subgroup IHD, n (%)

8 (8.0)

50 (38.8)

< 0.001

  Subgroup PH, n (%)

0 (0.0)

25 (19.4)

< 0.001

VC*, % predicted

88.9 ± 1.7

83.6 ± 1.8

0.033

FEV1*, % predicted

78.0 ± 2.0

64.6 ± 1.9

< 0.0001

FEV1/VC* %

65.7 ± 1.3

57.1 ± 1.3

< 0.0001

MEF50*, % predicted

41.8 ± 2.4

29.5 ± 2.1

< 0.0001

PaO2 , mmHg

74.5 ± 1.6

71.4 ± 1.0

NS

PaCO2 , mmHg

38.4 ± 0.5

39.8 ± 0.5

NS

CRP, mg/ml

3.4 ± 0.4

7.6 ± 0.7

< 0.0001

Beta adrenergic therapy, n (%)

94 (94.9)

97 (75.2)

0.0001

Corticosteroid therapy, n (%)

95 (96)

90 (69.8)

< 0.0001

Anticholinergic therapy, n (%)

22 (22)

76 (58.9)

<0.0001

  1. Value recorded before bronchodilator.