Table 2 Comparisons among patients without cardiovascular disease (no CVD), with pressure overload (PO) and volume overload (VO) in the overall study population
From: Predictors of cardiovascular disease in asthma and chronic obstructive pulmonary disease
ASTHMA + COPD | no CVD N. 44 | PO N. 97 | VO N. 88 | Univariate ANOVA | no CVD vs PO | no CVD vs VO | PO vs VO |
|---|---|---|---|---|---|---|---|
Age, years | 53.3 ± 1.3 | 64.3 ± 1.0 | 69.1 ± 1.1 | < 0.0001 | < 0.0001 | < 0.0001 | 0.002 |
Male, n (%) | 18 (40.9) | 43 (44.3) | 39 (44.3) | NS | NS | NS | NS |
BMI | 24.7 ± 0.7 | 26.9 ± 0.6 | 25.5 ± 0.5 | 0.038 | 0.028 | NS | NS |
VC, % pred. | 93.4 ± 2.2 | 85.1 ± 1.7 | 83.5 ± 2.4 | 0.011 | 0.005 | 0.006 | NS |
FEV1, % pred. | 82.6 ± 2.5 | 70.7 ± 2.1 | 64.8 ± 2.4 | < 0.0001 | 0.001 | < 0.0001 | NS |
FEV1/VC % | 67.6 ± 1.7 | 61.5 ± 1.5 | 56.7 ± 1.6 | < 0.0001 | 0.015 | < 0.0001 | 0.032 |
MEF50, % pred | 49.5 ± 4.1 | 35.8 ± 2.3 | 25.8 ± 2.3 | < 0.0001 | 0.002 | < 0.0001 | 0.003 |
CRP, mg/ml | 3.1 ± 0.6 | 5.9± 0.6 | 7.3 ± 1.0 | 0.011 | 0.009 | 0.007 | NS |