Table 4 Comparisons among patients without cardiovascular disease (no CVD), with pressure overload (PO) and volume overload (VO) in COPD
From: Predictors of cardiovascular disease in asthma and chronic obstructive pulmonary disease
COPD | no CVD N. 12 | PO N. 59 | VO N. 58 | Univariate ANOVA | no CVD vs PO | no CVD vs VO | PO vs VO |
|---|---|---|---|---|---|---|---|
Age, years | 58.5 ± 2.6 | 66.7 ± 1.3 | 72.4 ± 1.0 | < 0.0001 | 0.012 | < 0.0001 | 0.001 |
Male, n (%) | 9 (75) | 37 (62.7) | 32 (55.2) | NS | NS | NS | NS |
BMI | 25.4 ± 1.5 | 27.1 ± 0.7 | 25.4 ± 0.6 | NS | NS | NS | NS |
VC, % pred. | 91.8 ± 3.12 | 85.3 ± 2.4 | 80.0 ± 2.9 | NS | NS | NS | NS |
FEV1,% pred | 75.2 ± 4.8 | 66.3 ± 2.8 | 60.1 ± 2.8 | 0.048 | NS | 0.023 | NS |
FEV1/VC % | 61.5 ± 3.8 | 58.8 ± 2.0 | 54.4 ± 1.9 | NS | NS | NS | NS |
MEF50, % pred | 44.6 ± 10.2 | 34.5 ± 3.1 | 20.18 ± 2.1 | < 0.0001 | NS | < 0.0001 | < 0.0001 |
CRP, mg/ml | 4.4 ± 1.4 | 7.0 ± 0.9 | 8.9 ± 1.4 | NS | NS | NS | NS |