Table 2 Pulmonary function tests, muscle strength, thyroid function tests, SF-36 results and acute exacerbation frequency of COPD patients with and without hypothyroidism (Group 1 and 2)

FEV₁/FVC

67.2 ± 11.1

53.2 ± 15.6

0.001

FEV₁(L)

2.1 ± 0.7

2.01 ± 0.53

0.637

FEV₁(%)

83.1 ± 22.2

77.5 ± 16.2

0.339

FVC (L)

3.1 ± 0.9

3.67 ± 0.9

0.041

FVC (%)

100.1 ± 19.2

108.9 ± 21

0.15

FEF_25–75 (%)

47.5 ± 27.4

29.6 ± 12.3

0.009

TLC (%)

107.2 ± 19.5

105.3 ± 19

0.76

TLC (L)

5.9 ± 1.4

6.5 ± 1.5

0.306

MIP (cmH₂O)

69.6 ± 30.7

67.3 ± 17.5

0.77

MEP (cmH₂O)

25.6 ± 9.1

34.9 ± 11.5

0.006

TSH (mIU/mL)

4.3 (0.1–16.8)

0.8(0.3-3.6)

0.04

FT4 (pmol/L)

2.15 ± 3.27

2.36 ± 3.56

0.87

FT3 (pmol/L)

2.37 ± 0.77

2.73 ± 0.84

0.27

Acute exacerbation frequency (/years)

1.5 ± 0.85

0.86 ± 0.83

0.017

General health

35 (0–80)

45 (10–70)

0.383

Physical functioning

52.5 (0–100)

62.5 (25–95)

0.391

Physical role limitation

25 (0–100)

25 (0–100)

0.637

Emotional role limitation

33 (0–100)

33 (0–100)

0.608

Social functioning

50 (13–100)

56 (0–100)

0.972

Pain

60 (0–100)

85 (20–100)

0.179

Vitality

52.5 (10–85)

57.5 (20–92)

0.548

Mental health

52.5 (12–80)

58 (15–90)

0.249