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Table 2 Pulmonary function test results in healthy volunteers and acromegalic patients (absolute values)

From: Pulmonary function testing and chest tomography in patients with acromegaly

 

Control group (n = 20)

Acromegaly group (n = 20)

p

FVC (L)

3.27 ± 0.85

3.67 ± 1.03

0.186

FEV1 (L)

2.60 ± 0.65

2.92 ± 0.79

0.168

FEV1/FVC (%)

84.7 ± 3.25

79.8 ± 4.11

0.598

FEF25-75% (L/s)

2.61 ± 0.71

3.08 ± 1.16

0.130

FEF25-75%/FVC (%)

79.4 ± 6.06

83.6 ± 7.93

0.605

MIP (cm H2O)

-81.3 ± 29.4

-63.6 ± 28.9

0.063

MEP (cm H2O)

121 ± 32.9

92.3 ± 30.79

0.001

TLC (L)

4.83 ± 0.98

5.61 ± 1.09

0.023

RV (L)

1.55 ± 0.32

2.04 ± 0.38

<0.001

RV/TLC (%)

32.6 ± 6.89

37.5 ± 8.94

0.063

Raw (cm H2O/L/s)

2.31 ± 0.58

3.82 ± 0.49

0.039

DLCO (ml/min/mm Hg)

22.6 ± 5.66

23.3 ± 6.46

0.713

VA (L)

4.61 ± 1.33

4.92 ± 1.19

0.443

DLCO/VA (ml/min/mm Hg/L)

5.08 ± 1.06

4.72 ± 0.64

0.205

TLC-VA difference (L)

0.19 ± 0.61

0.69 ± 0.46

0.021

  1. Values are means ± SD or numbers (%). DLCO, diffusing capacity for carbon monoxide, FEF25-75%, forced expiratory flow during the middle half of the FVC; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; Raw, airway resistance; RV, residual volume; TLC, total lung capacity; VA, alveolar volume.