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Table 1 Demographic data, exposure characteristics, and lung function tests for the severe and mild groups

From: The association of human leukocyte antigen polymorphisms with disease severity and latency period in patients with silicosis

  Severe group** Mild group*** P Mean
Subjects (n) 28 20 - -
Age (years) 24.0 ± 9.5 23.4 ± 9.2 - NS*
BMI 22.3 ± 2.7 22.5 ± 3.0 - NS*
Total exposure duration (months) 35.7 ± 23.5 22.1 ± 21.1 0.004 Significant
Latency period (months) 58.1 ± 25.1 42.0 ± 30.6 0.044 Significant
Smoking (pack/years) 6.7 ± 2.3 5.9 ± 4.8 - NS*
FEV1 L 3.2 ± 0.8 3.8 ± 0.5 0.003 Significant
FEV1% pred 80.0 ± 19.9 93.5 ± 21.1 0.003 Significant
FVC L 3.8 ± 0.9 4.6 ± 0.8 0.005 Significant
FVC% pred 81.6 ± 18.3 96.0 ± 24.9 0.004 Significant
FEV1/FVC% 80.0 ± 9.0 84.7 ± 7.5 - NS*
  1. *NS, Not significant; **Severe, the cases with 1/1 or higher ILO profusion. ***Mild, the cases with1/0 or lower ILO profusion without any symptoms, but with proof of the disease on HRCT.