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Table 6 Studies of continuous 24-hour oximetry monitoring during activities of daily living

From: Ambulatory pulse oximetry monitoring in Japanese COPD outpatients not receiving oxygen therapy

Authors(Year)[Ref] N PaO2inclusion criteria Supplemental oxygen therapy PaO2PaCO2(mmHg) %FEV1 BMI Proportion of desaturators Mean proportion of SpO2values < 90%
Soguel Schenkel (1996) [18] 30 inpts Not defined 3 Patients* Median (range) Median (range) Median (range) Not described Not described
    68 (54–89) 37 (16–64) 25.5 (17.1–42.5)   
    42 (35–51)     
Casanova (2006) [11] 88 outpts 60–70 mmHg None Mean ± SD Mean ± SD Mean ± SD Daytime 22% Non-desaturators
64.7 ± 2.8 38 ± 13 27 ± 4 Nighttime 50%     24-hour 12.2%
45 ± 5.7         Daytime 8.9%
         Nighttime 18.8%
     Desaturators
         24-hour 55.1%
         Daytime 42.3%
         Nighttime 77.3%
Garcia-Talavera (2008) [3] 67 outpts 60–70 mmHg None Median (range) Median (range) Not described 24-hour 30% 24-hour 17%
66 (60–70) 37 (16–64)   Daytime 25% Daytime 15%
45 (32–57)    Nighttime 45% Nighttime 23%
Trauer (2012) [5] 35 outpts 56–70 mmHg None Mean ± SD Mean ± SD Mean ± SD 24-hour 54% 24-hour 41.9%
64.1 ± 4.5 37.5 ± 13.2 27.1 ± 7.0 Daytime 40% Daytime 30.9%
44.2 ± 6.0    Nighttime 77% Nighttime 60.6%
This study 39 outpts Not defined None Mean ± SD Mean ± SD Mean ± SD Daytime 0% Daytime 3.0%
78.2 ± 8.9 50.9 ± 18.5 23.1 ± 3.8 Nighttime 8% Nighttime 7.4%
39.1 ± 4.9     
  9 outpts** 60–70 mmHg None 66.2 ± 3.0 37.0 ± 14.6 23.9 ± 4.8 Daytime 0% Daytime 8.4%
38.0 ± 5.4    Nighttime 22% Nighttime 20.2%
  1. *Three patients had not previously received supplemental oxygen therapy, but started nocturnal oxygen therapy during admission to a pulmonary rehabilitation programme.
  2. **Nine patients in this study had more severe COPD with mild-to-moderate hypoxaemia (PaO2 60–70 mmHg).
  3. BMI, body mass index; FEV1, Forced expiratory volume in one second; Inpts, inpatients; Outpts, outpatients; PaO2, partial pressure of arterial oxygen; Ref, Reference; SD, Standard deviation; SpO2, Oxygen saturation by pulse oximetry.