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Table 3 Hemodynamic data according to diagnostic groups

From: Experience with exercise right heart catheterization in the diagnosis of pulmonary hypertension: a retrospective study

Diagnostic group

Resting precapillary PH, PAH (n = 28)

Exercise precapillary PH, ePAH (n = 13)

Resting postcapillary PH, PVH (n = 7)

Exercise postcapillary PH, ePVH (n = 12)

Exercise postcapillary out-of-proportion PH, eoPVH (n = 14)

No PH (n = 27)

Resting hemodynamics

 

HR, bpm

79 (69; 86.5)

71.5 (66; 83)

79 (74; 84)

70.5 (61; 74)

76 (70; 83)

78 (70; 86)

Mean BP, mmHg

91 (85; 104)

87 (78; 91)

110 (78; 126)

93 (86; 101)

95 (84; 101)

90 (86; 104)

Mean PAP, mmHg

32¶,* (26; 44)

20 (18; 21)

30¶,* (28; 34)

19§ (15; 22)

22 (19; 23)

15 (14; 18)

Diastolic PAP, mmHg

23¶,* (18; 31)

14 (12; 15)

21¶,* (19; 24)

12 (10; 15)

15 (13; 18)

11 (10; 14)

RAP, mmHg

8 (4.5; 9.5)

6 (4; 7)

9¶,* (7; 10)

5 (3; 8)

6 (4; 9)

5 (4; 7)

PAWP, mmHg

12¶,* (10; 13)

8 (8; 11)

17¶,* (17; 19)

12 (8; 14)

11 (9; 12)

8 (7; 10)

TPG, mmHg

23¶,* (17; 28)

9 (9; 12)

13¶,* (11; 14)

7§ (5; 8)

9 (9; 12)

7 (6; 9)

DPG, mmHg

10¶,* (8; 17)

5 (3; 7)

4 (1; 6)

1¶,§ (0; 3)

3 (2; 6)

2 (1; 3)

CI, l/min/m-2

3.0 (2.5; 3.5)

3.4 (2.8; 3.9)

3.2 (3.0; 4.8)

3.0 (2.75; 3.7)

3.5 (3.0; 4.0)

3.0 (2.7; 4.0)

CO, l/min

5.4 (4.1; 6.7)

6.3 (4.9; 7.2)

6.0 (5.0; 10.8)

5.3 (4.6; 7.0)

6.7 (5.5; 7.4)

5.1 (4.2; 6.8)

PVR, dynes*s*m-2

330¶,* (248; 415)

135 (112; 145)

193 (105; 247)

83¶,§ (63; 95)

122 (97; 175)

109 (90; 158)

SVR, dynes*s*m-2

1296 (1018; 1656)

1026 (898; 1382)

1031 (717; 1875)

1263 (948; 1562)

1196 (1026; 1331)

1340 (1101; 1761)

SaO2, %

90.5¶,* (87.8; 93.9)

95.0 (93.0; 95.3)

94.0 (93.0; 95.0)

94.8 (92.7; 96.0)

94.8 (93.0; 95.3)

94.8 (93.0; 96.0)

PaO2, kPA

8.2¶,* (7.6; 9.6)

10.6 (9.2; 11.7)

9.5 (8.9; 10.00)

10.2 (9.0; 11.7)

10.3 (9.4; 11.4)

11.4 (10.1; 12.2)

PaCO2, kPA

4.60 (4.32; 5.35)

4.65 (4.51; 4.80)

4.70 (4.49; 5.30)

4.85 (4.50; 5.27)

5.13 (4.60; 5.30)

5.05 (4.75; 5.40)

SmvO2, %

66.1¶,* (60.6; 70.5)

71.0 (69.0; 74.4)

70.0 (65.0; 71.0)

71.6 (68.4; 76.1)

71.4 (69.1; 73.5)

70.0 (65.4; 72.8)

Hemodynamics during supine maximal cycling exercise

 

Watt achieved

30 (20; 50)

30 (20; 40)

30 (20; 30)

30 (20; 50)

30 (20; 45)

30 (20; 40)

HR, bpm

110 (103; 123)

102 (98; 116)

111 (101; 118)

105 (98; 122)

116.5 (106; 122)

120 (101; 126)

Mean BP, mmHg

115 (101; 125)

107 (92; 114)

128 (102; 158)

107 (93; 120)

107 (103; 115)

101 (91; 113)

Mean PAP, mmHg

58¶,* (50; 66)

35 (32; 37)

47¶,* (42; 65)

36 (31; 41)

42 (38; 43)

24 (18; 27)

Increase in mPAP with exercise, mmHg

20¶,* (16; 30)

14(13; 19)

17(12; 31)

16(12; 25)

19 (14.7; 21)

7 (3; 9)

Increase in mPAP per Watt, mmHg

0.73 (0.53; 1.05)

0.47 (0.33; 0.74)

0.57 (0.40; 1.10)

0.48 (0.36; 0.77)

0.66 (0.35; 0.85)

0.20 (0.10; 0.33)

Diastolic PAP, mmHg

40¶,* (32; 45)

24 (22; 25)

30 (26; 40)

27 (24; 30)

30 (25; 31)

16 (12; 18)

RAP, mmHg

12¶,* (7; 17)

7 (3; 8)

16¶,* (9; 18)

10 (7; 11)

8 (6; 9)

5 (2; 7)

PAWP, mmHg

16¶,* (13; 21)

12 (10; 14)

32¶,* (27; 36)

26.5 (23; 34)

21.5 (17; 28)

10 (7; 15)

TPG, mmHg

41¶,* (34; 45)

22 (21; 29)

16 (8; 30)

9¶,§ (6; 12)

18 (16; 21)

12 (9; 14)

DPG, mmHg

21¶,* (13; 29)

11 (10; 13)

1 (-9; 7)

-1.5¶,§ (-6.5; 2.0)

5.5 (3; 9)

4 (2; 6)

CI, l/min/m-2

3.8 (3.0; 4.3)

4.0 (3.7; 4.7)

3.7 (3.3; 5.4)

3.7 (3.2; 4.1)

4.2 (3; 4.8)

3.8 (3.1; 4.3)

CO, l/min

6.8 (5.0; 8.3)

7.2 (6.7; 8.4)

6.5 (5.6; 12.1)

6.5 (5.5; 8.0)

7.06 (6.44; 8.83)

6.4 (4.8; 8.3)

PVR, dynes*s*m-2

487¶,* (398; 534)

251 (207; 335)

163 (100; 198)

97¶,§ (82; 119)

173.5 (148; 227)

139 (107; 229)

Delta PVR, dynes*s*m-2

126 (68; 208)

103 (73; 167)

15 (-89; 93)

16¶,§ (-9; 36)

57 (37; 97)

34 (11; 89)

SVR, dynes*s*m-2

1186 (866; 1679)

1031 (907; 1077)

1413 (739; 1541)

1164 (903; 1327)

989.5 (911; 1251)

1222 (933; 1755)

SaO2, %

88.0¶,* (80.0; 94.0)

95.0 (86.0; 96.0)

96.0 (94.0; 97.0)

94 (93; 95)

93.4 (91; 94.5)

96.0 (95.0; 97.0)

SmvO2, %

36.5¶,* (28.2; 43.5)

52.0 (38.0; 55.0)

45.0 (24.0; 50.0)

44.5 (33.5; 57.5)

50 (36; 58)

48.0 (40.0; 55.0)

  1. Data given as median (quartiles) or number (%). = p < .05 compared to patients with no PH. *= p < .05 compared to patients with appropriate exercise PH (either resting precapillary PH compared to exercise precapillary PH, or resting postcapillary PH compared to exercise postcapillary PH). §= p < .05 compared to exercise out-of-proportion PH.
  2. BP, Blood pressure; CI, Cardiac index; CO, Cardiac output; DPG, Diastolic pressure gradient; ePAH, Exercise precapillary pulmonary hypertension; eoPVH, Exercise postcapillary out-of-proportion pulmonary hypertension; ePVH, Exercise postcapillary pulmonary hypertension; HR, Heart rate; PaO 2 , Arterial oxygen partial pressure; PaCO 2 , Arterial carbon dioxide partial pressure; PAH, Pulmonary arterial hypertension; PAP, Pulmonary arterial pressure; PAWP, Pulmonary artery wedge pressure; PH, Pulmonary hypertension; PVH, Postcapillary pulmonary hypertension; PVR, Pulmonary vascular resistance; RAP, Right atrial pressure; SaO 2 , Arterial oxygen saturation; SmvO 2 , Mixed venous oxygen saturation; SVR, Systemic vascular resistance; TPG, Transpulmonary pressure gradient.
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Multidisciplinary Respiratory Medicine

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