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Table 3 Hemodynamic data according to diagnostic groups

From: Experience with exercise right heart catheterization in the diagnosis of pulmonary hypertension: a retrospective study

Diagnostic group Resting precapillary PH, PAH (n = 28) Exercise precapillary PH, ePAH (n = 13) Resting postcapillary PH, PVH (n = 7) Exercise postcapillary PH, ePVH (n = 12) Exercise postcapillary out-of-proportion PH, eoPVH (n = 14) No PH (n = 27)
Resting hemodynamics  
HR, bpm 79 (69; 86.5) 71.5 (66; 83) 79 (74; 84) 70.5 (61; 74) 76 (70; 83) 78 (70; 86)
Mean BP, mmHg 91 (85; 104) 87 (78; 91) 110 (78; 126) 93 (86; 101) 95 (84; 101) 90 (86; 104)
Mean PAP, mmHg 32¶,* (26; 44) 20 (18; 21) 30¶,* (28; 34) 19§ (15; 22) 22 (19; 23) 15 (14; 18)
Diastolic PAP, mmHg 23¶,* (18; 31) 14 (12; 15) 21¶,* (19; 24) 12 (10; 15) 15 (13; 18) 11 (10; 14)
RAP, mmHg 8 (4.5; 9.5) 6 (4; 7) 9¶,* (7; 10) 5 (3; 8) 6 (4; 9) 5 (4; 7)
PAWP, mmHg 12¶,* (10; 13) 8 (8; 11) 17¶,* (17; 19) 12 (8; 14) 11 (9; 12) 8 (7; 10)
TPG, mmHg 23¶,* (17; 28) 9 (9; 12) 13¶,* (11; 14) 7§ (5; 8) 9 (9; 12) 7 (6; 9)
DPG, mmHg 10¶,* (8; 17) 5 (3; 7) 4 (1; 6) 1¶,§ (0; 3) 3 (2; 6) 2 (1; 3)
CI, l/min/m-2 3.0 (2.5; 3.5) 3.4 (2.8; 3.9) 3.2 (3.0; 4.8) 3.0 (2.75; 3.7) 3.5 (3.0; 4.0) 3.0 (2.7; 4.0)
CO, l/min 5.4 (4.1; 6.7) 6.3 (4.9; 7.2) 6.0 (5.0; 10.8) 5.3 (4.6; 7.0) 6.7 (5.5; 7.4) 5.1 (4.2; 6.8)
PVR, dynes*s*m-2 330¶,* (248; 415) 135 (112; 145) 193 (105; 247) 83¶,§ (63; 95) 122 (97; 175) 109 (90; 158)
SVR, dynes*s*m-2 1296 (1018; 1656) 1026 (898; 1382) 1031 (717; 1875) 1263 (948; 1562) 1196 (1026; 1331) 1340 (1101; 1761)
SaO2, % 90.5¶,* (87.8; 93.9) 95.0 (93.0; 95.3) 94.0 (93.0; 95.0) 94.8 (92.7; 96.0) 94.8 (93.0; 95.3) 94.8 (93.0; 96.0)
PaO2, kPA 8.2¶,* (7.6; 9.6) 10.6 (9.2; 11.7) 9.5 (8.9; 10.00) 10.2 (9.0; 11.7) 10.3 (9.4; 11.4) 11.4 (10.1; 12.2)
PaCO2, kPA 4.60 (4.32; 5.35) 4.65 (4.51; 4.80) 4.70 (4.49; 5.30) 4.85 (4.50; 5.27) 5.13 (4.60; 5.30) 5.05 (4.75; 5.40)
SmvO2, % 66.1¶,* (60.6; 70.5) 71.0 (69.0; 74.4) 70.0 (65.0; 71.0) 71.6 (68.4; 76.1) 71.4 (69.1; 73.5) 70.0 (65.4; 72.8)
Hemodynamics during supine maximal cycling exercise  
Watt achieved 30 (20; 50) 30 (20; 40) 30 (20; 30) 30 (20; 50) 30 (20; 45) 30 (20; 40)
HR, bpm 110 (103; 123) 102 (98; 116) 111 (101; 118) 105 (98; 122) 116.5 (106; 122) 120 (101; 126)
Mean BP, mmHg 115 (101; 125) 107 (92; 114) 128 (102; 158) 107 (93; 120) 107 (103; 115) 101 (91; 113)
Mean PAP, mmHg 58¶,* (50; 66) 35 (32; 37) 47¶,* (42; 65) 36 (31; 41) 42 (38; 43) 24 (18; 27)
Increase in mPAP with exercise, mmHg 20¶,* (16; 30) 14(13; 19) 17(12; 31) 16(12; 25) 19 (14.7; 21) 7 (3; 9)
Increase in mPAP per Watt, mmHg 0.73 (0.53; 1.05) 0.47 (0.33; 0.74) 0.57 (0.40; 1.10) 0.48 (0.36; 0.77) 0.66 (0.35; 0.85) 0.20 (0.10; 0.33)
Diastolic PAP, mmHg 40¶,* (32; 45) 24 (22; 25) 30 (26; 40) 27 (24; 30) 30 (25; 31) 16 (12; 18)
RAP, mmHg 12¶,* (7; 17) 7 (3; 8) 16¶,* (9; 18) 10 (7; 11) 8 (6; 9) 5 (2; 7)
PAWP, mmHg 16¶,* (13; 21) 12 (10; 14) 32¶,* (27; 36) 26.5 (23; 34) 21.5 (17; 28) 10 (7; 15)
TPG, mmHg 41¶,* (34; 45) 22 (21; 29) 16 (8; 30) 9¶,§ (6; 12) 18 (16; 21) 12 (9; 14)
DPG, mmHg 21¶,* (13; 29) 11 (10; 13) 1 (-9; 7) -1.5¶,§ (-6.5; 2.0) 5.5 (3; 9) 4 (2; 6)
CI, l/min/m-2 3.8 (3.0; 4.3) 4.0 (3.7; 4.7) 3.7 (3.3; 5.4) 3.7 (3.2; 4.1) 4.2 (3; 4.8) 3.8 (3.1; 4.3)
CO, l/min 6.8 (5.0; 8.3) 7.2 (6.7; 8.4) 6.5 (5.6; 12.1) 6.5 (5.5; 8.0) 7.06 (6.44; 8.83) 6.4 (4.8; 8.3)
PVR, dynes*s*m-2 487¶,* (398; 534) 251 (207; 335) 163 (100; 198) 97¶,§ (82; 119) 173.5 (148; 227) 139 (107; 229)
Delta PVR, dynes*s*m-2 126 (68; 208) 103 (73; 167) 15 (-89; 93) 16¶,§ (-9; 36) 57 (37; 97) 34 (11; 89)
SVR, dynes*s*m-2 1186 (866; 1679) 1031 (907; 1077) 1413 (739; 1541) 1164 (903; 1327) 989.5 (911; 1251) 1222 (933; 1755)
SaO2, % 88.0¶,* (80.0; 94.0) 95.0 (86.0; 96.0) 96.0 (94.0; 97.0) 94 (93; 95) 93.4 (91; 94.5) 96.0 (95.0; 97.0)
SmvO2, % 36.5¶,* (28.2; 43.5) 52.0 (38.0; 55.0) 45.0 (24.0; 50.0) 44.5 (33.5; 57.5) 50 (36; 58) 48.0 (40.0; 55.0)
  1. Data given as median (quartiles) or number (%). = p < .05 compared to patients with no PH. *= p < .05 compared to patients with appropriate exercise PH (either resting precapillary PH compared to exercise precapillary PH, or resting postcapillary PH compared to exercise postcapillary PH). §= p < .05 compared to exercise out-of-proportion PH.
  2. BP, Blood pressure; CI, Cardiac index; CO, Cardiac output; DPG, Diastolic pressure gradient; ePAH, Exercise precapillary pulmonary hypertension; eoPVH, Exercise postcapillary out-of-proportion pulmonary hypertension; ePVH, Exercise postcapillary pulmonary hypertension; HR, Heart rate; PaO 2 , Arterial oxygen partial pressure; PaCO 2 , Arterial carbon dioxide partial pressure; PAH, Pulmonary arterial hypertension; PAP, Pulmonary arterial pressure; PAWP, Pulmonary artery wedge pressure; PH, Pulmonary hypertension; PVH, Postcapillary pulmonary hypertension; PVR, Pulmonary vascular resistance; RAP, Right atrial pressure; SaO 2 , Arterial oxygen saturation; SmvO 2 , Mixed venous oxygen saturation; SVR, Systemic vascular resistance; TPG, Transpulmonary pressure gradient.