From: Metabolomic profile of amniotic fluid to evaluate lung maturity: the diaphragmatic hernia lamb model
Age III AF | MS peak area | Fold difference | Adjusted p | t | MS peak area | Fold difference | Adjusted p | t | MS peak area | Fold difference | Adjusted p | t | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabolites | Control | CDH | Control | CDH + TO | CDH + TO | CDH | |||||||||
Betaine | 91450 | 17210 | 5.31 | 0.000 | 47.02 | 91450 | 27990 | 3.27 | 0.000 | 39.33 | 27990 | 17210 | 1.63 | 0.001 | 16.43 |
± | ± | ± | ± | ± | ± | ||||||||||
2646 | 566 | 2646 | 901 | 901 | 566 | ||||||||||
Choline | 6281 | 1639 | 3.83 | 0.001 | 19.36 | 6281 | 3933 | 1.60 | 0.015 | 10.84 | 3933 | 1639 | 2.40 | 0.042 | 22.10 |
± | ± | ± | ± | ± | ± | ||||||||||
375 | 146 | 375 | 14 | 14 | 146 | ||||||||||
Creatinine | 189533 | 20330 | 9.32 | 0.001 | 37.36 | 189533 | 118833 | 1.60 | 0.002 | 14.21 | 118833 | 20330 | 5.84 | 0.001 | 46.59 |
± | ± | ± | ± | ± | ± | ||||||||||
7821 | 495 | 7821 | 3612 | 3612 | 495 |