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Table 1 Baseline characteristics for O2 users and O2 non-users with fILDs

From: Supplemental oxygen users with pulmonary fibrosis perceive greater dyspnea than oxygen non-users

 

O2 (N = 812)

No O2 (N = 514)

P-

Age (years)

68.3 ± 10.5

66.6 ± 11.0

0.004

Female (%)

327 (40.3)

211 (41.1)

0.78

Smoking*

4 (0.6 %)

3 (0.6 %)

0.003

 Present

471 (65.9 %)

277 (57.4 %)

 

 Past

240 (33.6 %)

203 (42.0 %)

 

 Never

   

BMI

30.3 ± 6.9

28.5 ± 5.5

<0.0001

IPF diagnosis (%)

303 (37.3)

170 (33.1)

0.12

FVC% within 30 days**

61.3 ± 18.9

77.5 ± 17.4

<0.0001

DLCO% within 30 days***

37.5 ± 12.8

56.1 ± 16.5

<0.0001

6MWD (feet)

1070.6 ± 361.4

1421.4 ± 343.7

<0.0001

Borg Dyspnea

3.9 ± 2.0

2.9 ± 1.7

<0.0001

Borg Exertion****

3.2 ± 2.1

2.4 ± 1.8

<0.0001

HR baseline

79.7 ± 13.9

78.1 ± 13.2

0.03

HR at 6 min

109.7 ± 15.9

110.9 ± 15.8

0.18

HR rise

30.0 ± 14.5

32.8 ± 13.7

0.0004

SpO2 baseline

97.4 ± 1.9

95.2 ± 1.7

<0.0001

SpO2 at 6 min

88.1 ± 5.3

88.7 ± 5.4

0.04

SpO2 drop

9.2 ± 5.5

6.4 ± 5.2

<0.0001

  1. Values are mean and standard deviation or count (percent); IPF idiopathic pulmonary fibrosis; BMI body mass index; FVC% percent predicted forced vital capacity; DLCO% percent predicted diffusing capacity of the lung for carbon monoxide; 6MWD distance walked during six-minute walk test (6MWT); SpO2 peripheral oxygen saturation; HR heart rate; O2 completed 6MWT using supplemental oxygen; No O2 completed 6MWT without using supplemental oxygen; *N = 715 for O2 users and 483 for non-users; **N = 446 for O2 users and 251 for non-users; ***N = 211 for O2 users and 123 for non-users; ****N = 672 for O2 users and 415 for non-users