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Table 5 Linear univariate regression analysis of the questionnaire dimensions

From: Mental health, serum biomarkers and survival in severe COPD: a pilot study

Explanatory Variable

B Slope (95 % CI)

p*

Univariate analyses

HADS anxiety

  

 Age (years)

−0.11 (-0.217-(-0.002))

0.045

 VC (%)

−0.06 (-0.104-(-0.015))

0.01

 FEV1 (%)

−0.1 (-0.174-(-0.02))

0.015

 6-MWD (%)

−0.09 (-0.136-(-0.035))

0.002

 RV/ TLC

0.042 (0.012-0.072)

0.007

HADS depression

 Hb (g/dl)

−0.94 (-1.838-(-0.041))

0.041

 Hc (%)

−0.3 (-0.577-(-0.029))

0.031

 6-MWD (%)

−0.12 (-0.234-(-0.012))

0.031

PHQ-15 (somatisation)

 6-MWD (%)

−0.15 (-0.276-(-0.025))

0.021

PHQ-stress

 Leucocytes (103/μl)

0.4 (0.013-0.777)

0.043

SGRQ-total

 6-MWD

−0.44 (-0.714-(-0.166))

0.003

STAI-state anxiety

 VC (%)

−0.23 (-0.453-(-0.01))

0.041

STAI-trait anxiety

 Leucocytes (103/μl)

1.1 (0.1117-2.089)

0.03

 SA-A (mg/l)

0.17 (0.055-0.276)

0.005

  1. *Only the significant (p ≤ 0.05) variables are shown. The questionnaire dimensions were the dependent variables
  2. 6-MWD, six-minute walk test, ESR erythrocyte sedimentation rate, FEV1, forced expiratory volume in 1 s, Hb haemoglobin, Hc haematocrit, SA-A serum amyloid-A, RV residual volume, TLC total lung capacity, VC vital capacity, HADS Hospital Anxiety and Depression Scale, PHQ Patient Health Questionnaire, SGRQ St. George’s Respiratory Questinnaire, STAI State-trait anxiety inventory
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Multidisciplinary Respiratory Medicine

ISSN: 2049-6958

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