Mental health, serum biomarkers and survival in severe COPD: a pilot study

Table 6 Multivariate linear regression analysis of the questionnaire dimensios

Explanatory Variable	Slope (95 % Cl)	p	Model R²
HADS Anxiety
RV/TLC	0.02 (-0.017-0.056)	0.272
6-MWD (%)	−0.072 (-0.128-(-0.016))	0.014	0.401
VC (%)	−0.027 (-0.090-0.037)	0.391
6-MWD (%)	−0.078 (-0.132-(-0.024))	0.024	0.394
FEV₁ (%)	−0.079 (-0.124-0.065)	0.519
6-MWD (%)	−0.030 (-0.135-(-0.024))	0.008	0.384
HADS Depression
6-MWD (%)	−0.111 (-0.227-0.005)	0.059
Hc (%)	−0.168 (-0.600-0.265)	0.429	0.228
6-MWD (%)	−0.111 (-0.228-(-0.005))	0.042
Hb (g/dl)	−0.635 (-1.917-0.646)	0.314	0.243

25-OHD 25-OH-cholecalciferol, 6-MWD six-minute walk test, ESR erythrocyte sedimentation rate, FEV1 ₁ forced expiratory volume in 1 s, Hb haemoglobin, Hc haematocrit, RV residual volume, SA-A serum amyloid-A, TLC total lung capacity, VC vital capacity, HADS Hospital Anxiety and Depression Scale, STAI State-trait anxiety inventory. Questionnaire dimensions were the dependent variables
Highlighted in bold: p ≤ 0.05

ISSN: 2049-6958