Table 5 Individual symptoms
Individual symptoms | Visit | Absence of symptom | χ 2-Test | ||||
|---|---|---|---|---|---|---|---|
CalSuli-4-02 N = 99 | Control N = 101 | (df) statistics | p | ||||
N | % | N | % | ||||
Fever | Baseline (day 0) | 82 | 82.8 | 79 | 78.2 | - | - |
2nd FU (day 21) | 94 | 95.0 | 94 | 93.1 | (1) 0.380 | 0.5377 | |
3rd FU (3 months p-t) | 93 | 93.9 | 92 | 91.1 | (1) 0.803 | 0.3701 | |
Termination (6 months p-t) | 96 | 97.0 | 98 | 97.0 | (1) 0.000 | 0.9884 | |
Nasal discharge (rhinorrhea/mucopurulent) | Baseline (day 0) | 42 | 42.4 | 46 | 45.5 | - | - |
2nd FU (day 21) | 82 | 82.8 | 86 | 85.2 | (2) 0.218 | 0.8968 | |
3rd FU (3 months p-t) | 84 | 84.9 | 86 | 85.2 | (1) 0.003 | 0.9554 | |
Termination (6 months p-t) | 90 | 90.9 | 92 | 91.1 | (2) 1.079 | 0.5832 | |
Skin pallor | Baseline (day 0) | 42 | 42.4 | 37 | 36.6 | - | - |
2nd FU (day 21) | 65 | 65.7 | 55 | 54.5 | (1) 2.660 | 0.1029 | |
3rd FU (3 months p-t) | 74 | 74.8 | 66 | 65.4 | (1) 2.223 | 0.1360 | |
Termination (6 months p-t) | 80 | 80.8 | 73 | 72.3 | (1) 2.184 | 0.1395 | |
Rales in lungs | Baseline (day 0) | 87 | 87.9 | 87 | 86.1 | - | - |
2nd FU (day 21) | 97 | 98.0 | 98 | 97.0 | (2) 2.985 | 0.2248 | |
3rd FU (3 months p-t) | 95 | 96.0 | 92 | 91.1 | (1) 2.806 | 0.0939 | |
Termination (6 months p-t) | 97 | 98.0 | 97 | 96.0 | (1) 1.980 | 0.1594 | |
Restlessness for unknown reason | Baseline (day 0) | 77 | 77.8 | 85 | 84.2 | - | - |
2nd FU (day 21) | 91 | 91.9 | 94 | 93.1 | (2) 1.362 | 0.5061 | |
3rd FU (3 months p-t) | 97 | 98.0 | 97 | 96.0 | (1) 1.980 | 0.1594 | |
Termination (6 months p-t) | 94 | 95.0 | 97 | 96.0 | (2) 1.027 | 0.5985 | |
Atopic dermatitis manifestations | Baseline (day 0) | 61 | 61.6 | 66 | 65.4 | - | - |
2nd FU (day 21) | 73 | 73.7 | 72 | 71.3 | (2) 0.675 | 0.7137 | |
3rd FU (3 months p-t) | 82 | 82.8 | 76 | 75.3 | (3) 3.208 | 0.3607 | |
Termination (6 months p-t) | 88 | 88.9 | 81 | 80.2 | (3) 5.070 | 0.1667 | |
Child’s activities impairment | Baseline (day 0) | 63 | 63.6 | 71 | 70.3 | - | - |
2nd FU (day 21) | 93 | 93.9 | 82 | 81.2 | (2) 8.218 | 0.0164 | |
3rd FU (3 months p-t) | 92 | 92.9 | 87 | 86.1 | (1) 3.002 | 0.0832 | |
Termination (6 months p-t) | 95 | 96.0 | 87 | 86.1 | (1) 7.475 | 0.0063 | |