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Table 1 General and clinical parameters in 294 COPD patients stratified for GOLD stages and divided in two groups, based on VAT 50th percentile (2183 g for men; 912.5 g for women)

From: Preliminary study on the assessment of visceral adipose tissue using dual-energy x-ray absorptiometry in chronic obstructive pulmonary disease

 

GOLD I + II (n. 132)

GOLD III (n. 112)

GOLD IV (n. 50)

 

VAT < 50th

VAT > 50th

P

VAT < 50th

VAT > 50th

P

VAT < 50th

VAT > 50th

P

Age (years)

65.3 ± 10.9

64.9 ± 9.2

0.856

65.1 ± 10.4

65.7 ± 6.8

0.697

59.6 ± 7.5

59,1 ± 10.5

0.868

BMI (kg/m2)

24.0 ± 3.5

31.9 ± 4.4

<0.001

21.6 ± 2.9

30.5 ± 4.8

<0.001

20.7 ± 3.4

28.1 ± 4.5

<0.001

FFMI (kg/m2)

16.7 ± 2.4

18.7 ± 2.6

<0.001

15.5 ± 1.7

17.9 ± 2.5

<0.001

14.6 ± 1.4

16.9 ± 2

<0.001

FMI (kg/m2)

7.5 ± 2.0

13.2 ± 3.0

<0.001

6.4 ± 2.4

12.7 ± 3.1

<0.001

6.2 ± 2.6

11.3 ± 2.9

<0.001

Gynoid Fat (g)

3322.2 ± 1005.5

5517.6 ± 1314.4

<0.001

2770.4 ± 1031.5

5148.4 ± 1572.9

<0.001

2810.2 ± 1251.9

4737.4 ± 1397.2

<0.001

Android Fat (g)

1797.3 ± 769.0

4120.8 ± 1110.6

<0.001

1428,9 ± 736.2

3997.5 ± 1274.8

<0.001

1336.6 ± 760.1

3641.8 ± 1513.6

<0.001

FEV1 (% pred)

70.6 ± 20.6

68.9 ± 13.5

0.572

38.5 ± 5.5

39.6 ± 5.7

0.306

23.4 ± 5.0

25.2 ± 3.1

0.181

FEV1/FVC (%)

46.8 ± 11.3

49.4 ± 9.6

0.160

31.5 ± 6.7

33.4 ± 7.4

0.157

22.9 ± 4.4

26.2 ± 7.3

0.050

IVC (% pred)

115.9 ± 19.5

108.1 ± 18.7

0.021

96.3 ± 17.0

93.0 ± 15.9

0.289

79.8 ± 15.4

78.4 ± 15.0

0.750

ITGV (% pred)

132.9 ± 27.6

112.5 ± 21.9

<0.001

163.6 ± 33.1

146.0 ± 27.1

0.003

193.4 ± 35.1

174.6 ± 37.6

0.090

ERV (% pred)

132.6 ± 46.4

106.9 ± 44.9

0.002

130.6 ± 40.1

112.2 ± 35.1

0.012

106.4 ± 29.8

90.4 ± 35.9

0.103

RV (% pred)

134.0 ± 33.7

116.1 ± 26.9

0.001

178.3 ± 40.3

159.3 ± 32.6

0.008

234.5 ± 61.8

212.9 ± 48.8

0.226

IC/TLC (%)

37.9 ± 8.2

42.6 ± 7.2

0.001

26.6 ± 7.7

30.2 ± 6.5

0.008

20.3 ± 5.4

24.0 ± 5.2

0.027

DLCO (% predicted)

54.8 ± 15.9

65.5 ± 22.6

0.002

42.7 ± 12.9

50.6 ± 12.5

0.003

33.6 ± 13.1

45.1 ± 16.4

0.015

  1. Values reported as mean ± standard deviation
  2. BMI body mass index, FFM fat-free mass index, FMI fat mass index, FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, IVC max inspiratory vital capacity, ITGV intra-thoracic gas volume, ERV expiratory reserve volume, RV residual volume, IC inspiratory capacity, TLC total lung capacity, DLCO diffusing capacity of the lung for carbon monoxide
  3. Statistically significant p are indicated in bold characters