Table 1 Patients' background characteristics
rhTM group (n = 10) | Untreated group (n = 13) | p | |
|---|---|---|---|
Baseline characteristics | |||
Male, n | 8 | 11 | 0.8 |
Age | 73.2 ± 9.5 | 69.7 ± 8.5 | 0.3 |
Pulmonary function prior to acute exacerbation | |||
FVC (ml) | 2200 ± 910 (n = 8) | 1630 ± 570 (n = 7) | 0.1 |
%FVC (% predicted) | 68.1 ± 24.1 (n = 8) | 58.6 ± 16.7 (n = 7) | 0.3 |
PaO2 (mmHg) | 68.9 ± 6.5 (n = 6) | 64.4 ± 10.2 (n = 8) | 0.4 |
Treatment of IPF prior to acute exacerbation | |||
Pirfenidone | 2/10 | 0/13 | |
Steroids | 0/10 | 0/13 | |
Immunosuppressant (cyclosporine) | 0/10 | 0/13 | |
Anticoagulant therapy | 0/10 | 0/13 | |
Home oxygen therapy | 2/10 | 2/13 | |