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Table 2 Incidence rate of target events (venous thromboembolism, deep venous thrombosis)

From: Mutational status predicts the risk of thromboembolic events in lung adenocarcinoma

Variable

Target event (n)

Incidence rate (95% CI)

Mutation status:

 EGFR+

15

0.21 (0.10–0.32)

 ALK+

13

0.27 (0.13–0.42)

 Unexposed group

25

0.22 (013–0.31)

Gender:

 Female

31

0.21 (0.14–0.29)

 Male

22

0.26 (0.15–0.37)

Age

  < 66 years

38

0.33 (0.22–0.43)

  > 66 years

15

0.13 (0.06–0.19)

Stadium

 I

4

0.05 (0.01–0.10)

 II

6

0.21 (0.04–0.37)

 III

9

0.18 (0.06–0.30)

 IV

34

0.46 (0.30–0.61)

Smoking status:

 Never smoker

17

0.26 (0.14–0.38)

 Ex-smoker

14

0.18 (0.11–0.26)

 Smoker

22

0.26 (0.14–0.38)

 Hypertension

12

0.14 (0.06–0.22)

 Diabetes

0

-

 AC before the event

7

0.24 (0.06–0.42)

Treatment options:

 CTP alone

30

1.00 (0.55–1.45)

 Other treatment without TKI

4

0.11 (0.05–0.17)

 Other treatment with TKI

 

0.25 (0.13–0.38)

 TKI alone

19

0.15 (0.04–0.29)

  1. Incidence rate (x1000 person/days) in relation to mutation status, baseline clinical features, and treatment options
  2. Abbreviations: EGFR+ patients bearing a mutation in the epidermal growth factor receptor (EGFR), ALK+ patients bearing a rearrangement of the anaplastic lymphoma kinase (ALK), AC anticoagulants, preventive dose for venous thromboembolism, CTP standard chemotherapy, TKI tyrosine kinase inhibitors