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Table 2 Temperature and humidity

From: Criteria for enhancing mucus transport: a systematic scoping review

Publication

Human

Animal/Lab

Temperature range

Humidity

Tracheal mucus transport measurement method

Effect on mucus Transport

Diesel et al. 1991

 

x

35-39.5 °C

 

Timing of particles as they travelled the 1-cm distance from 1 grid bar to the next

↓ with ↓ temp

Eckerbom et al. 1991

 

x

 

HME vs no HME

Bronchoscopy and gamma camera

↑ with HME

Kilgour et al. 2004

 

x

30-37 °C

100% relative humidity

Timing movement of reflective particles in the mucus across a calibrated eyepiece graticule

↓ with ↓ temp

Lippman et al. 1975

 

x

−10° - 30 °C

 

Rectilinear scanner and the calculated time required for a bolus of tagged particles to move a fixed distance along the trachea

↓ with ↓ temp

Puchelle et al. 1989

 

x

 

Absolute humidity of 9 g water/m3 vs 30 g water/m3

Ciliary transport capacity analysed using the frog palate technique and transport velocity assessed by measuring transit time to pass over a 2 mm portion of the palate

↓ with ↓ humidity

Sears et al. 2015

 

x

0 - 37 °C

37 - 25 °C

24.5 – 39.5 °C

 

Microscopy and reviewing videos and tracking the motion of individual particles.

↑ with ↑ temp

↓ with ↓ temp