From: Criteria for enhancing mucus transport: a systematic scoping review
Publication | Human | Animal/Lab | Temperature range | Humidity | Tracheal mucus transport measurement method | Effect on mucus Transport |
---|---|---|---|---|---|---|
Diesel et al. 1991 | x | 35-39.5 °C | Timing of particles as they travelled the 1-cm distance from 1 grid bar to the next | ↓ with ↓ temp | ||
Eckerbom et al. 1991 | x | HME vs no HME | Bronchoscopy and gamma camera | ↑ with HME | ||
Kilgour et al. 2004 | x | 30-37 °C | 100% relative humidity | Timing movement of reflective particles in the mucus across a calibrated eyepiece graticule | ↓ with ↓ temp | |
Lippman et al. 1975 | x | −10° - 30 °C | Rectilinear scanner and the calculated time required for a bolus of tagged particles to move a fixed distance along the trachea | ↓ with ↓ temp | ||
Puchelle et al. 1989 | x | Absolute humidity of 9 g water/m3 vs 30 g water/m3 | Ciliary transport capacity analysed using the frog palate technique and transport velocity assessed by measuring transit time to pass over a 2 mm portion of the palate | ↓ with ↓ humidity | ||
Sears et al. 2015 | x | 0 - 37 °C 37 - 25 °C 24.5 – 39.5 °C | Microscopy and reviewing videos and tracking the motion of individual particles. | ↑ with ↑ temp ↓ with ↓ temp |