Skip to main content

Table 1 Patients who discontinued pirfenidone more than 1 day prior to transplantation

From: Effect of pirfenidone on wound healing in lung transplant patients

Variable

Patient 1

Patient 2

Patient 3

Patient 4

Age, years

59

68

67

69

Number of days before LTx pirfenidone was stopped

6

15

16

21

Pirfenidone dose at time of discontinuation

801 mg PO TID

801 mg PO TID

801 mg PO TID

801 mg PO TID

Duration of pirfenidone treatment

30-90 days

> 90 days

30-90 days

< 30 days

Reason for stopping pirfenidone

VV ECMO BTT with feeding tube

ECMO BTT with feeding tube

Cost

Adverse GI effects

Prednisone dose at LTx

10 mg PO daily

10 mg PO daily

20 mg PO daily

None

  1. Abbreviations: BTT bridge to transplantation, GI gastrointestinal, LTx lung transplantation, PO per oral, TID ter in die (3 times per day), VV ECMO venovenous extracorporeal membrane oxygenation