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Table 2 Results of 5-hmC immunohistochemistry analysis

From: 5-hydroxymethylcytosine but not MTAP methylation status can stratify malignant pleural mesothelioma based on the lineage of origin

5-hmC IHC

Positive

Negative

MPM

E

5

13

S

9

6

B

5

2

RHM

 

6

19

COP

 

5

15

NSCLC

ADC

0

25

SCC

0

25

IPF

 

0

15

Healthy lung

0

25

Sensitivity MPM/RMH = 47%

  

Specificity MPM/RMH = 76%

  

Sensitivity E/B + S = 63%

  

Specificity E/B + S = 72%

  
  1. E stands for epitheliod MPM, S: sarcomatoid, B: biphasic types
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Multidisciplinary Respiratory Medicine

ISSN: 2049-6958

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