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Table 2 Comparison among different tests to measure cystic fibrosis transmembrane conductance regulator (CFTR) ion channel activity

From: When and how ruling out cystic fibrosis in adult patients with bronchiectasis

  Qualitative Quantitative Validated Clinical Research
Sweat test   X X X X
CFTR gene analysis X   X X X
NPD   X X X X
ICM   X X X X
Ratiometric sweat secretion optical test   X    X
Monocyte assay   X    X
  1. CFTR cystic fibrosis transmembrane conductance regulator; NPD nasal potential difference; ICM intestinal current measurement