When and how ruling out cystic fibrosis in adult patients with bronchiectasis

Table 2 Comparison among different tests to measure cystic fibrosis transmembrane conductance regulator (CFTR) ion channel activity

	Qualitative	Quantitative	Validated	Clinical	Research
Sweat test		X	X	X	X
CFTR gene analysis	X		X	X	X
NPD		X	X	X	X
ICM		X	X	X	X
Ratiometric sweat secretion optical test		X			X
Monocyte assay		X			X

CFTR cystic fibrosis transmembrane conductance regulator; NPD nasal potential difference; ICM intestinal current measurement

ISSN: 2049-6958