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Table 1 Definitions of AECOPD according to the GOLD document, NICE guidelines and ERS/ATS guidelines

From: Management of severe acute exacerbations of COPD: an updated narrative review

GOLD document Acute worsening of respiratory symptoms that results in additional therapy.
NICE guidelines A worsening of the patient’s symptoms from their usual stable state which is beyond normal day-to-day variations, and is acute in onset. Commonly reported symptoms are worsening breathlessness, cough, increased sputum production and change in sputum colour. The change in these symptoms often necessitates a change in medication.
ERS/ATS guidelines Episodes of increasing respiratory symptoms, particularly dyspnea, cough and sputum production, and increased sputum purulence
  1. Reported from references [1, 9, 10]