Table 1 Demographics of patients with idiopathic pulmonary fibrosis in the 2 study groups
Characteristic | All IPF | IPF and LC | IPF only | P |
|---|---|---|---|---|
Subjects No. (%) | 246 (100) | 34 (13.8) | 212 (86.2) | 0.000 |
Age,± SD, y | 52.4 ± 8.2 | 56.6 ± 10.0 | 47.7 ± 10.2 | 0.002 |
Gender No. (%) | 0.107 | |||
Male | 171 (69.5) | 28(82.3) | 143 (67.4) | |
Female | 75 (30.5) | 6 (17.7) | 69 (32.6) | |
Smoking status | 0.033 | |||
Current | 180 (73.2) | 22 (64.6) | 158 (74.4) | |
Past | 31 (12.6) | 4 (11.8) | 27 (12.8) | |
Never | 35 (14.2) | 8 (23.6) | 27 (12.8) | |
Pack/years | 33.4 ± 16.7 | 37.2 ± 21.7 | 30.7 ± 13.1 | 0.016 |
FVC (% pred) | 80.8 ± 2.9 | 85.9 ± 2.7 | 77.1 ± 3.8 | 0.000 |
FEV1(% pred) | 82.3 ± 5.0 | 87.0 ± 4.8 | 76.9 ± 5.9 | 0.010 |
TLC (% pred) | 69.2 ± 10.1 | 70.1 ± 12.8 | 67.8 ± 9.3 | 0.206 |
DLCO (% pred) | 60.2 ± 8.3 | 57.1 ± 10.4 | 62.6 ± 9.5 | 0.000 |
Diagnostic method | 0.021 | |||
Clinical | 218 (88.6) | 26 (76.5) | 192 (90.6) | |
Surgical | 28 (11.4) | 8 (23.5) | 20 (9.4) | |
AEIPF | 87 (35.3) | 18 (53) | 69 (32.5) | 0.032 |