| References | Amoxicillin/clavulanic acid | Cefuroxime | Cefditoren | |||
---|---|---|---|---|---|---|---|
MIC50 | MIC90 | MIC50 | MIC90 | MIC50 | MIC90 | ||
Streptococcus pyogenes a | 13–15 | ≤0.012–0.06 | ≤0.012–0.12 | 0.03–0.06 | 0.12 | ≤0.03 | ≤0.03–0.06 |
Streptococcus pneumoniae b | 14,15,41–48 |  |  |  |  |  |  |
 Penicillin-susceptible |  | ≤0.015–0.06 | 0.03–0.25 | ≤0.03 | 0.12–0.25 | ≤0.015 | ≤0.03–0.06 |
 Penicillin-intermediate |  | 0.25–1 | 1–4 | 0.5–4 | 4–8 | 0.06–0.25 | 0.25–0.5 |
 Penicillin-resistant |  | 2 - ≥16 | 8 - ≥16 | 4–8 | 8–32 | 0.25–0.5 | 0.5–1 |
Haemophilus influenzae | |||||||
 β-lactamase negative | 14,15,22,41,44 | 0.25–1 | 1–8 | 0.25–2 | 1–8 | ≤0.08 | ≤0.03–0.06 |
 β-lactamase positive | 14,15,22,41,44 | 0.5–2 | 2–4 | 1–2 | 2–8 | ≤0.08 | ≤0.03–0.06 |
 BLNAR | 14,15,65 | 2 | 4 | 0.5–4 | 2–16 | ≤0.08 | 0.03–0.06 |
 BLPACR | 65 | 4 | 8 | 4 | 16 | 0.03 | 0.06 |
Moraxella catarrhalis (β-lactamase positive) | 14,15,22,23 | 0.12–0.5 | 0.25–2 | 1 | 2–8 | 0.06–0.12 | 0.25–0.5 |