Skip to main content

Table 2 A comprehensive summary of indications for AATD testing across documents for the clinical management of chronic respiratory disease

From: Alpha-1 antitrypsin deficiency as a common treatable mechanism in chronic respiratory disorders and for conditions different from pulmonary emphysema? A commentary on the new European Respiratory Society statement

Document

Disease

Indications for AATD testing

Global strategy for prevention, diagnosis and management of COPD, 2018 [49]

COPD

All patients with a diagnosis of COPD, especially in areas with high AATD prevalence

Global strategy for asthma management and prevention, 2018 [50]

Asthma

No indication for AATD testing

European Respiratory Society, 2017 [54]

Bronchiectasis

Patients with basal emphysema or early onset airflow obstruction

Pulmonology Portuguese Society Bronchiectasis Study Group, 2018 [53]

Bronchiectasis

All patients with a diagnosis of BE

Thoracic Society of Australia and New Zealand, 2015 [62]

Bronchiectasis

No indication for AATD testing

British Thoracic Society, 2010 [51]

Bronchiectasis

Patients with basal emphysema.

Normativa SEPAR, 2008 [52]

Bronchiectasis

Patients with emphysema and /or liver disease