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Table 2 Indicators of the severity of SARI by pathogen and age

From: Clinical characteristics and outcomes of patients with severe acute respiratory infections (SARI): results from the Egyptian surveillance study 2010–2014

  SARI cases RSV Adenovirus Influenza Multiple Viruses
No (%) OR (95%
CI)
P* No (%) OR (95% CI) P$ No (%) OR (95% CI) P$ No (%) OR (95% CI) P$ No (%) OR (95% CI) P$
All participants
 Ventilation 100/
1,075
(9)
1.280
(0.703-
2.329
0.419 43/485
(9)
0.177
(−1.005-
0.185)
0.866 7/105
(7)
1.293
(0.682-
2.452)
0.431 17/77
(22)
3.123
(1.743-
5.598)
0.000 13/174
(7)
0.755
(0.412-
1.386)
0.365
 ICU 219/
1,075
(20)
0.972
(0.706-
1.337)
0.861 82/485
(17)
1.897
(12.591-
13.635)
0.017 22/105
(21)
1.040
(0.634-
1.707)
0.876 36/77
(47)
3.910
(2.431-
6.290)
0.000 41/174
(23)
0.225
(0.162-
0.612)
0.254
 Death 24/
1,075
(2)
0.00
(0.941-
0.966)
0.557 12/485
(2)
0.530
(−1.215-
0.625)
0.637 2/105
(2)
0.837
(0.194-
3.609)
0.811 4/77
(5)
0.986
(−0.114-
2.085)
0.079 4/174
(2)
0.036
(1.050-
1.122)
0.948
 Severe Outcome 219/
1,075
(20)
0.972
(0.706-
1.337)
0.861 82/485
(17)
1.433
(4.698-
6.132)
0.021 22/105
(21)
1.047
(0.638-
1.738)
0.857 36/77
(47)
3.937
(2.447-
6.334)
0.000 41/174
(23)
0.232
(0.155-
0.619)
0.240
Children <18 years
 Ventilation 66/
981
(7)
1.032
(0.305-
3.541)
0.952 36/485
(8)
0.894
(0.566-
1.413)
0.632 7/105
(7)
0.907
(04.05-
2.032)
0.812 5/77
(6)
1.785
(0.676-
4.713)
.0243 13/174
(7)
0.995
(0.536-
1.849)
0.988
 ICU 178/
981
(18)
0.983
(0.503-
1.924)
0.961 68/485
(14)
0.838
(0.594-
1.182)
0.314 11/105
(10)
0.691
(0359-
1.330)
0.268 10/77
(13)
2.008
(0.952-
(4.237)
0.067 32/174
(18)
1.418
(0.921-
2.185)
0.113
 Death 13/
981
(1)
0.973
(0.960-
(0.987)
0.784 12/485
(2)
1.363
(0.583-
1.385)
0.474 2/105
(2)
0.966
(0.222-
4.198)
0.963 2/77
(2)
2.640
(0.594-
11.740)
0.202 4/174
(2)
1.162
(0.338-
3.479)
0.789
 Severe Outcome 178/
981
(18)
0.983
(0.503-
1.924)
0.961 68/485
(14)
0.849
(0.602-
1.199)
0.353 11/105
(10)
0.697
(0.362-
1.342)
0279 10/77
(13)
2.024
(0.959-
4.271)
0.064 32/174
(18)
1.432
(0929-
2.206)
0.114
Adults >18 years
 Ventilation 34/94
(36)
1.357
(0.645-
2.856)
0.421 7/485
(1)
0.966
(0.114-
2.085)
0.078 0/105
(0)
2.991
(0.851-
10.514)
0.088 12/77
(16)
2.878
(1014-
8.166)
0.052 0/174
(0)
0.787
(0.669-
0.885)
0.063
 ICU 41/94
(44)
1.100
(0.704-
1.718)
0.675 14/485
(3)
1.493
(0.282-
2.452)
0.527 11/105
(10)
3.235
(0.671-
15.593)
0.143 26/77
(34)
0.929
(0.392-
2.198)
0.866 9/174
(5)
0.606
(0.203-
1.815)
0.371
 Death 11/94
(12)
0.934
(0.912-
0.965)
0.793 0/485
(0)
0.848
(0.437-
1.196)
0.691 11/105
(10)
0.859
(0.790-
0.933)
0.645 2/77
(2)
0.413
(0.324-
0.527)
0.351 0 (0) 0.826
(0.752-
0.907)
0.763
 Severe Outcome 41/94
(44)
1.100
(0.704-
1.718)
0.675 14/485
(3)
1.493
(0.282-
2.452)
0.527 0/105
(0)
3.235
(0.671-
15.593)
0.143 26/77
(34)
0.929
(0.392-
2.198)
0.866 9/174
(5)
0.606
(0.203-
1.815)
0.371
  1. *P for comparison between virus-infected (SARI-positive) and non-infected (SARI-negative) individuals. P$ for SARI patients with a positive result for that pathogen compared to a reference group of tested SARI patients with a negative result for that pathogen. RSV Respiratory syncytial virus, PIV Para-influenza virus, ICU Intensive care unit, Severe outcome is defined as illness requiring ventilation or ICU or resulting in death