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Table 2 Bronchoalveolar lavage fluid concentrations of MMP-7, IL-4Rα, PAR-2 and TNF-α in the whole group at the time of diagnosis and in progressor and nonprogressor subgroups

From: Bronchoalveolar lavage cell profiles and proteins concentrations can be used to phenotype extrinsic allergic alveolitis patients

  EAA -whole group n = 71 Progressors n = 14 Nonprogressors n = 34
MMP-7 (ng/ml) 2.26 (0.24–5.37) 2.54 ± 1.77 1.93 (0.59–7.68) 2.72 ± 2.47 2.23 (0.24–5.37) 2.48 ± 1.52
IL-4Rα (pg/ml) 745.3 (0–2365.0) 723.11 ± 716.67 758.0 (32.0–2342.0) 1003.4 ± 863.1 451.0 (0–2365.0) 633.6 ± 648.8
PAR-2 (ng/ml) 827.0 (279.0–10,000.0) 2192.89 ± 2654.1 1163.0 (451.0–7353.2) 1796.7 ± 1947.5 1377.8 (279.0–\.0) 2311.7 ± 2838.1
TNF-α (pg/ml) 2.89 (0–7.58) 2.88 ± 2.82 2.17 (0–5.32) 2.54 ± 2.42 3.45 (0–7.56) 2.91 ± 2.43
  1. EAA Extrinsic allergic alveolitis, MMP-7 Matrix metalloproteinase 7, IL-4Rα Interleukin 4 receptor α, PAR-2 Protease activated receptor 2, TNF-α Tumor necrosis factor α. Data are expressed as median (min-max) and mean ± SD