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Table 2 Bronchoalveolar lavage fluid concentrations of MMP-7, IL-4Rα, PAR-2 and TNF-α in the whole group at the time of diagnosis and in progressor and nonprogressor subgroups

From: Bronchoalveolar lavage cell profiles and proteins concentrations can be used to phenotype extrinsic allergic alveolitis patients

 

EAA -whole group n = 71

Progressors n = 14

Nonprogressors n = 34

MMP-7 (ng/ml)

2.26 (0.24–5.37)

2.54 ± 1.77

1.93 (0.59–7.68)

2.72 ± 2.47

2.23 (0.24–5.37)

2.48 ± 1.52

IL-4Rα (pg/ml)

745.3 (0–2365.0)

723.11 ± 716.67

758.0 (32.0–2342.0)

1003.4 ± 863.1

451.0 (0–2365.0)

633.6 ± 648.8

PAR-2 (ng/ml)

827.0 (279.0–10,000.0)

2192.89 ± 2654.1

1163.0 (451.0–7353.2)

1796.7 ± 1947.5

1377.8 (279.0–\.0)

2311.7 ± 2838.1

TNF-α (pg/ml)

2.89 (0–7.58)

2.88 ± 2.82

2.17 (0–5.32)

2.54 ± 2.42

3.45 (0–7.56)

2.91 ± 2.43

  1. EAA Extrinsic allergic alveolitis, MMP-7 Matrix metalloproteinase 7, IL-4Rα Interleukin 4 receptor α, PAR-2 Protease activated receptor 2, TNF-α Tumor necrosis factor α. Data are expressed as median (min-max) and mean ± SD