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Table 1 Changes in dehydration-related outcomes considered to be of clinical interest between study visits

From: Observational study of the effects of upper respiratory tract infection on hydration status

Outcome Change of Interest
Serum osmolality > 5%
Urine specific gravity > 5%
Urine osmolality > 10%
Urine color > 2 colors
Hematocrit > 5%
Serum urea and electrolytes
 Sodium > 5%
 Potassium > 5%
 Bicarbonate > 5%
 Urea > 10%
 Chloride > 5%
Complete blood count
 Hemoglobin > 5%
 Red blood cell count > 5%
 Hematocrit > 5%
 Mean cell volume > 5%
 Mean cell hemoglobin > 5%
 Mean cell hemoglobin concentration > 5%
 White cell count > 10%
 Platelet count > 10%
Body weight > 1%
BMI > 1%
Subjective assessments of thirst and hydration
 Subject ratingsa > 5%
 Physician ratingsb
  Skin > 1 point
  Tongue > 1 point
  Mucous membrane > 1 point
  General appearance > 1 point
  1. aRated by subject on a visual analog scale ranging from 0 = no thirst at all to 100 = worst thirst ever experienced
  2. bRated by physician on a scale of 0 = no evidence of dehydration, 1 = some dehydration, 2 = moderate dehydration, and 3 = severe dehydration
  3. BMI body mass index, URTI upper respiratory tract infection