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Table 1 Changes in dehydration-related outcomes considered to be of clinical interest between study visits

From: Observational study of the effects of upper respiratory tract infection on hydration status

Outcome

Change of Interest

Serum osmolality

> 5%

Urine specific gravity

> 5%

Urine osmolality

> 10%

Urine color

> 2 colors

Hematocrit

> 5%

Serum urea and electrolytes

 Sodium

> 5%

 Potassium

> 5%

 Bicarbonate

> 5%

 Urea

> 10%

 Chloride

> 5%

Complete blood count

 Hemoglobin

> 5%

 Red blood cell count

> 5%

 Hematocrit

> 5%

 Mean cell volume

> 5%

 Mean cell hemoglobin

> 5%

 Mean cell hemoglobin concentration

> 5%

 White cell count

> 10%

 Platelet count

> 10%

Body weight

> 1%

BMI

> 1%

Subjective assessments of thirst and hydration

 Subject ratingsa

> 5%

 Physician ratingsb

  Skin

> 1 point

  Tongue

> 1 point

  Mucous membrane

> 1 point

  General appearance

> 1 point

  1. aRated by subject on a visual analog scale ranging from 0 = no thirst at all to 100 = worst thirst ever experienced
  2. bRated by physician on a scale of 0 = no evidence of dehydration, 1 = some dehydration, 2 = moderate dehydration, and 3 = severe dehydration
  3. BMI body mass index, URTI upper respiratory tract infection