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  1. Content type: Original research article

    COPD is one of the leading causes of morbidity and mortality. Pharmacotherapy improves quality of life and reduces exacerbations although low adherence with prescribed treatments may represent a barrier to opt...

    Authors: G. De Filippi, M. Lallini, G. De Riggi, G. Marchetti, C. M. Dimartino, A. M. Russetti, E. Ferrari, R. Pistelli, M. S. Magnoni, M. Riparbelli, A. Rizzi and P. Angeletti

    Citation: Multidisciplinary Respiratory Medicine 2017 12:18

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  2. Content type: Original research article

    Precision medicine promises to improve prognosis of patients affected by untreatable diseases. Patients with lung cancer (especially lung adenocarcinoma) bear an increased risk of VTE. Mutations in the EGFR an...

    Authors: Elsa Davidsson, Nicola Murgia, Cristian Ortiz-Villalón, Emil Wiklundh, Magnus Sköld, Karl Gustav Kölbeck and Giovanni Ferrara

    Citation: Multidisciplinary Respiratory Medicine 2017 12:16

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  3. Content type: State of the Art

    Medical approach to patients is a fundamental step to get the correct diagnosis. The aim of this paper is to analyze some aspects of the reasoning process inherent in medical diagnosis in our era. Pathologic s...

    Authors: Gino Soldati, Andrea Smargiassi, Alberto A. Mariani and Riccardo Inchingolo

    Citation: Multidisciplinary Respiratory Medicine 2017 12:15

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  4. Content type: Original research article

    Inhalation is the preferred route for respiratory drug delivery, but several factors contribute to the variability of the respirable dose fraction. Instant velocity and the dynamic characteristics of the dropl...

    Authors: Roberto W. Dal Negro, Pietro Longo, Orestepaolo Villanis Ziani, Luca Bonadiman and Paola Turco

    Citation: Multidisciplinary Respiratory Medicine 2017 12:13

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  5. Content type: Review

    Pulmonary drug delivery is currently the focus of accelerated research and development because of the potential to produce maximum therapeutic benefit to patients by directly targeting drug to the site of path...

    Authors: Federico Lavorini, Massimo Pistolesi and Omar S. Usmani

    Citation: Multidisciplinary Respiratory Medicine 2017 12:11

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    The Erratum to this article has been published in Multidisciplinary Respiratory Medicine 2017 12:19

  6. Content type: Original research article

    To date, an important aspect that has still not been clarified is the assessment of OHS severity. The purpose of this retrospective study was to evaluate whether grading OHS severity according to PaCO2 values may...

    Authors: Mario Francesco Damiani, Vito Antonio Falcone, Pierluigi Carratù, Cristina Scoditti, Elioda Bega, Silvano Dragonieri, Alfredo Scoditti and Onofrio Resta

    Citation: Multidisciplinary Respiratory Medicine 2017 12:14

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  7. Content type: Research Article

    Hypersensitivity pneumonitis (HP) is a common diffuse parenchymal lung disease in Egypt which can be difficult to recognize due to the dynamic symptoms & associated environmental factors.

    Authors: Dalia Abd El-Kareem, Yosri M. Akl, Gina A. Nakhla, Ali A. Elhindawi and Mahmoud A. Eltorky

    Citation: Multidisciplinary Respiratory Medicine 2017 12:10

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  8. Content type: Review

    Severe and poorly controlled asthma still accounts for a great portion of the patients affected. Disease control and future risk management have been identified by international guidelines as the main goals in...

    Authors: Dejan Radovanovic, Pierachille Santus, Francesco Blasi and Marco Mantero

    Citation: Multidisciplinary Respiratory Medicine 2017 12:12

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    The Erratum to this article has been published in Multidisciplinary Respiratory Medicine 2017 12:17

  9. Content type: Review

    Information and Communication Technologies applied to health care and advances in sensor and data transmission technology allowed tele-medicine based programs of care also for patients with respiratory diseases.

    Authors: Nicolino Ambrosino, Dewi Nurul Makhabah and Yusup Subagio Sutanto

    Citation: Multidisciplinary Respiratory Medicine 2017 12:9

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  10. Content type: Original research article

    The intratracheal instillation of bleomycin in mice induces early damage to alveolar epithelial cells and development of inflammation followed by fibrotic tissue changes and represents the most widely used mod...

    Authors: Francesca Ruscitti, Francesca Ravanetti, Jeroen Essers, Yanto Ridwan, Sasha Belenkov, Wim Vos, Francisca Ferreira, Alex KleinJan, Paula van Heijningen, Cedric Van Holsbeke, Antonio Cacchioli, Gino Villetti and Franco Fabio Stellari

    Citation: Multidisciplinary Respiratory Medicine 2017 12:8

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  11. Content type: Original research article

    Life-long regular use of drugs is necessary in chronic diseases like asthma and COPD. There are several methods to improve adherence including patient information and education; however, their effectiveness on...

    Authors: Gábor Tomisa, Alpár Horváth, Brigitta Dombai and Lilla Tamási

    Citation: Multidisciplinary Respiratory Medicine 2017 12:6

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  12. Content type: Letter to the Editor

    Ventilator associated pneumonia currently in vogue seems to have some pitfalls as far as the nomenclature is concerned and thus it imparts an erroneous impression to the reader. As the driving force is in fact...

    Authors: Zahid Hussain Khan, Piero Ceriana and Claudio F. Donner

    Citation: Multidisciplinary Respiratory Medicine 2017 12:5

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  13. Content type: Letter to the Editor

    It is estimated that about 60–70% of Cystic Fibrosis patients develop Pseudomonas aeruginosa chronic infection, with progressive loss of lung function, as well as increased antibiotic resistance and mortality.

    Authors: Marco Mantero, Andrea Gramegna, Giovanna Pizzamiglio, Alice D’Adda, Paolo Tarsia and Francesco Blasi

    Citation: Multidisciplinary Respiratory Medicine 2017 12:2

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  14. Content type: Original research article

    Isolated cases of pulmonary arterial hypertension (PAH) with interferon α or β therapy have been reported, but no population-based estimates of the incidence of the disease after interferon exposure are availa...

    Authors: Ravikanth Papani, Alexander G. Duarte, Yu-li Lin, Yong-Fang Kuo and Gulshan Sharma

    Citation: Multidisciplinary Respiratory Medicine 2017 12:1

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  15. Content type: Original research article

    The year 2015 marked the end of United Nations Millennium Development Goals which was aimed at halting and reversing worldwide tuberculosis (TB). The emergence of drug resistance is a major challenge for world...

    Authors: Waleed M. Sweileh, Adham S. AbuTaha, Ansam F. Sawalha, Suleiman Al-Khalil, Samah W. Al-Jabi and Sa’ed H. Zyoud

    Citation: Multidisciplinary Respiratory Medicine 2017 11:45

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  16. Content type: Original research article

    Asthma is a common disease of the airways with a significant burden for the society and for patients’ quality of life. The Social Impact of Respiratory Integrated Outcomes (SIRIO) study estimated a mean cost o...

    Authors: Roberto W. Dal Negro, Chiara Distante, Luca Bonadiman, Paola Turco and Sergio Iannazzo

    Citation: Multidisciplinary Respiratory Medicine 2016 11:44

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  17. Content type: Original research article

    We hypothesized that the use of oxygen supplementation during aerobic exercise induces less DNA damage than exercise alone.

    Authors: Andréa Lúcia Gonçalves da Silva, Thaís Evelyn Karnopp, Augusto Ferreira Weber, Cassia da Luz Goulart, Paloma de Borba Scheneiders, Dannuey Machado Cardoso, Lisiane Lisboa Carvalho, Joel Henrique Ellwanger, Lia Gonçalves Possuelo and Andréia Rosane de Moura Valim

    Citation: Multidisciplinary Respiratory Medicine 2016 11:43

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  18. Content type: Original research article

    Health-care professionals have a responsibility to be attentive to patients’ adherence behavior but it could be difficult to identify poor adherence in the context of clinical practice. Assessment of personali...

    Authors: Malin Axelsson, Linda Ekerljung, Bo Lundbäck and Jan Lötvall

    Citation: Multidisciplinary Respiratory Medicine 2016 11:42

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  19. Content type: Original research article

    Hemothorax after lung transplantation may result in increased post-operative morbidity and mortality. Risk factors for developing hemothorax and the outcomes of patients who develop hemothorax have not been we...

    Authors: Aria Hong, Christopher S. King, A. Whitney Walter Brown, Shahzad Ahmad, Oksana A. Shlobin, Sandeep Khandhar, Linda Bogar, Anthony Rongione and Steven D. Nathan

    Citation: Multidisciplinary Respiratory Medicine 2016 11:40

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  20. Content type: Original research article

    This report is based on an independent study carried out by medical professionals of the Fondazione IRCCS Istituto Nazionale dei Tumori (National Cancer Institute) in Milan, Italy, and  aimed to assess the inc...

    Authors: Carla Valenti, Paolo Pozzi, Alessandra Busia, Roberto Mazza, Paolo Bossi, Cinzia De Marco, Ario Alberto Ruprecht, Alessandro Borgini and Roberto Boffi

    Citation: Multidisciplinary Respiratory Medicine 2016 11:41

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  21. Content type: Original research article

    Coagulation abnormalities are involved in the pathogenesis of acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF). The administration of recombinant human soluble thrombomodulin (rhTM), which has bot...

    Authors: Sho Hayakawa, Yasuo Matsuzawa, Tamako Irie, Hagino Rikitake, Noriaki Okada and Yasuo Suzuki

    Citation: Multidisciplinary Respiratory Medicine 2016 11:38

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  22. Content type: Letter to the Editor

    In the absence of randomisation, observational studies must take extra care to create treatment groups that are comparable in terms of key characteristics. Various matching methods exist which can create sound...

    Authors: David B. Price, Job F. M. van Boven, Lisa M. Law, Alessandra Cifra and R. Brett McQueen

    Citation: Multidisciplinary Respiratory Medicine 2016 11:39

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  23. Content type: Review

    Despite major advances in the treatment of asthma and the development of several asthma guidelines, people still die of asthma currently. According to WHO estimates, approximately 250,000 people die prematurel...

    Authors: Gennaro D’Amato, Carolina Vitale, Antonio Molino, Anna Stanziola, Alessandro Sanduzzi, Alessandro Vatrella, Mauro Mormile, Maurizia Lanza, Giovanna Calabrese, Leonardo Antonicelli and Maria D’Amato

    Citation: Multidisciplinary Respiratory Medicine 2016 11:37

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  24. Content type: Original research article

    The aim of this study is to evaluate the presence of neurocognitive dysfunctions, depression and anxiety and the effect of positive airway pressure (PAP) therapy on these alterations in Obesity Hypoventilation...

    Authors: Serap Argun Baris, Dilek Tuncel, Cigdem Ozerdem, Huseyin Kutlu, Tugba Onyilmaz, Ilknur Basyigit, Hasim Boyaci and Fusun Yildiz

    Citation: Multidisciplinary Respiratory Medicine 2016 11:35

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  25. Content type: Original research article

    Visceral adipose tissue (VAT) was shown to be increased in patients with chronic obstructive pulmonary disease (COPD) compared to control subjects with comparable body mass index (BMI). Our aim was to determin...

    Authors: Francesca De Blasio, Erica P. A. Rutten, Emiel F. M. Wouters, Luca Scalfi, Francesco De Blasio, Marco A. Akkermans, Martijn A. Spruit and Frits M. E. Franssen

    Citation: Multidisciplinary Respiratory Medicine 2016 11:33

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  26. Content type: Original research article

    Cough is one of the most common discomforts affecting general population, which can disrupt subjects’ quality of life due to its physical, social, and psychological effects. Aim of the study was to investigate...

    Authors: Roberto W. Dal Negro, Massimiliano Mazzolini, Paola Turco and Alessandro Zanasi

    Citation: Multidisciplinary Respiratory Medicine 2016 11:34

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  27. Content type: Original research article

    Inhalation devices represent per sé critical factors because they can affect the therapeutic outcomes independently of the drug used. The role of patients’ usability and preference (PUP) for Dry Powder Inhalers (...

    Authors: Roberto W. Dal Negro and Massimiliano Povero

    Citation: Multidisciplinary Respiratory Medicine 2016 11:31

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  28. Content type: Original research article

    An increasing number of inhalation devices are presently available in the market. They are differently characterized in terms of their handling and usability, both factors which may affect the outcomes of resp...

    Authors: Roberto W. Dal Negro and Massimiliano Povero

    Citation: Multidisciplinary Respiratory Medicine 2016 11:32

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  29. Content type: Review

    Obesity is currently one of the major epidemics of this millennium and affects individuals throughout the world. It causes multiple systemic complications, some of which result in severe impairment of organs a...

    Authors: Thiago Thomaz Mafort, Rogério Rufino, Cláudia Henrique Costa and Agnaldo José Lopes

    Citation: Multidisciplinary Respiratory Medicine 2016 11:28

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  30. Content type: Original research article

    The air inhaled by people is abundantly populated with microorganisms which also are called bioaerosols. Bioaerosols is a colloidal suspension, formed by liquid droplets and particles of solid matter in the ai...

    Authors: Zemichael Gizaw, Mulat Gebrehiwot and Chalachew Yenew

    Citation: Multidisciplinary Respiratory Medicine 2016 11:24

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  31. Content type: Original research article

    The present study reports the results of a survey jointly carried out by three Italian respiratory scientific associations (AIMAR, AIPO, SIMeR) together with an important Federation of elderly patients (FederA...

    Authors: Nicola Ciancio, Claudio M. Sanguinetti, Franco Falcone, Claudio Taranto, Roberto Fasani, Fernando De Benedetto, Onofrio Resta, Fausto De Michele, Roberto Messina, Andrea Rossi, Stefano Nardini and Giuseppe Di Maria

    Citation: Multidisciplinary Respiratory Medicine 2016 11:26

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  32. Content type: Case report

    Sarcoidosis is a systemic granulomatous disease of unknown origin, characterized by the formation of granulomas without central necrosis. Each organ and tissue can be affected by the disease, but in most cases...

    Authors: Livio G. Moccia, Sabrina Castaldo, Emanuela Sirignano, Maddalena Napolitano, Enrica Barra and Alessandro Sanduzzi

    Citation: Multidisciplinary Respiratory Medicine 2016 11:27

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  33. Content type: Original research article

    Early identification and control of pathogenic bacteria are important in the treatment of pneumonia. Currently, two rapid antigen detection kits for pneumococcal pneumonia are available: one uses urine samples...

    Authors: Shoji Suzuki, Naoki Nishimura, Torahiko Jinta, Yasuhiko Yamano, Genta Ishikawa, Yutaka Tomishima, Noboru Uchiyama and Naohiko Chohnabayashi

    Citation: Multidisciplinary Respiratory Medicine 2016 11:25

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  34. Content type: Original research article

    Acute cough is one of the most frequent symptoms prompting a visit to a health care provider, usually following a viral upper respiratory tract infection (URTI). The disproportionate use of antibiotics in chil...

    Authors: Alessandro Zanasi, Luigi Lanata, Federico Saibene, Giovanni Fontana, Peter V. Dicpinigaitis, Valentina Venier and Francesco De Blasio

    Citation: Multidisciplinary Respiratory Medicine 2016 11:29

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  35. Content type: Original research article

    Dry powder inhalers (DPIs) are the most commonly used devices in asthma treatment in the Nordic countries. As new DPIs become available, patients are likely to be exposed to more than one type of device, with ...

    Authors: Birger Norderud Lærum, Gunilla Telg and Georgios Stratelis

    Citation: Multidisciplinary Respiratory Medicine 2016 11:21

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  36. Content type: Original research article

    Asthma is a disease with high cost for the National Health Service. Two of the most recent LABA/ICS combinations for persistent bronchial asthma are Beclomethasone dipropionate/Formoterol (B/F) delivered via t...

    Authors: Roberto W. Dal Negro, Chiara Distante, Luca Bonadiman, Paola Turco and Sergio Iannazzo

    Citation: Multidisciplinary Respiratory Medicine 2016 11:20

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  37. Content type: Original research article

    Hypoventilation produces or worsens respiratory acidosis in patients with hypercapnia due to acute exacerbations of chronic obstructive pulmonary disease (AECOPD). In these patients acid–base and hydroelectrol...

    Authors: Alfonso Schiavo, Maurizio Renis, Mario Polverino, Arcangelo Iannuzzi and Francesca Polverino

    Citation: Multidisciplinary Respiratory Medicine 2016 11:23

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  38. Content type: Original research article

    The present study was initiated to investigate the effectiveness, safety and tolerability of complex homeopathic CalSuli-4-02 tablets on prevention of recurrent acute upper respiratory tract infections (URTIs)...

    Authors: Miek C. Jong, Stephen L. Buskin, Lydia Ilyenko, Irina Kholodova, Julia Burkart, Stephan Weber, Thomas Keller and Petra Klement

    Citation: Multidisciplinary Respiratory Medicine 2016 11:19

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  39. Content type: Original research article

    There is limited information on prevalence of pulmonary tuberculosis (PTB) in patients with type-1-diabetes. We assessed the prevalence of PTB in patients with type-1-diabetes attending the outpatient-clinic i...

    Authors: Abilash Nair, Randeep Guleria, Devasenathipathy Kandasamy, Raju Sharma, Nikhil Tandon, Urvashi B. Singh and Ravinder Goswami

    Citation: Multidisciplinary Respiratory Medicine 2016 11:22

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  40. Content type: Review

    The inflammatory diseases of the nose, rhino-pharynx and paranasal sinuses (allergic and non allergic rhinitis, NARES; rhinosinusitis with/without nasal polyposis, adenoidal hypertrophy with/without middle ear...

    Authors: Desiderio Passali, Maria Carla Spinosi, Anna Crisanti and Luisa Maria Bellussi

    Citation: Multidisciplinary Respiratory Medicine 2016 11:18

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  41. Content type: Original research article

    Self-expandable metallic stents (SEMS) can be used to treat malignant obstructions and fistulas of the central airways. SEMS can be placed using different methods. Recently, a rigid bronchoscope has been used ...

    Authors: Cengiz Özdemir, Sinem Nedime Sökücü, Levent Karasulu, Seda Tural Önür and Levent Dalar

    Citation: Multidisciplinary Respiratory Medicine 2016 11:15

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  42. Content type: Case report

    Tracheobronchopathia Osteochondroplastica (TBPO) is an uncommon and benign condition characterized by osseous or metaplastic cartilaginous 1–3 mm nodules in the submucosa of the tracheo-bronchial tree. Posteri...

    Authors: Alessandro G. Fois, Antonella Arcadu, Luigi Santoru, Rocco Trisolini, Vincenzo Marras, Giorgio C. Ginesu, Sara Canu, Lorenzo Cordero, Gabriella Diana and Pietro Pirina

    Citation: Multidisciplinary Respiratory Medicine 2016 11:16

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