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  1. Content type: Original Research Article

    Exertional dyspnea is a hallmark symptom of fibrosing interstitial lung disease (fILD), and oxygen (O2) desaturation is common among patients with fILD. Supplemental O2 is prescribed to maintain normoxia and alle...

    Authors: Mengshu Cao, Frederick S. Wamboldt, Kevin K. Brown, Jonathon Hickman, Amy L. Olson, Joshua J. Solomon and Jeffrey J. Swigris

    Citation: Multidisciplinary Respiratory Medicine 2015 10:37

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  2. Content type: Original research article

    Weaning from tracheostomy has implications in management, quality of life, and costs of ventilated patients. Furthermore, endotracheal cannula removing needs further studies. Aim of this study was the validati...

    Authors: Franco Pasqua, Ilaria Nardi, Alessia Provenzano and Alessia Mari

    Citation: Multidisciplinary Respiratory Medicine 2015 10:35

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  3. Content type: Original research article

    Inflammatory airway disease (IAD) in horses, similar to asthma in humans, is a common cause of chronic poor respiratory health and exercise intolerance due to airway inflammation and exaggerated airway constri...

    Authors: Ashley Houtsma, Daniela Bedenice, Nicola Pusterla, Brenna Pugliese, Samantha Mapes, Andrew M Hoffman, Julia Paxson, Elizabeth Rozanski, Jean Mukherjee, Margaret Wigley and Melissa R. Mazan

    Citation: Multidisciplinary Respiratory Medicine 2015 10:33

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  4. Content type: Letter to the Editor

    There is limited evidence supporting the routine use of palivizumab in paediatric cystic fibrosis (CF) patients to reduce respiratory syncytial virus (RSV) infection and related hospitalisation. Despite this, ...

    Authors: Barry Linnane, Miranda G. Kiernan, Nuala H. O’Connell, Linda Kearse and Colum P. Dunne

    Citation: Multidisciplinary Respiratory Medicine 2015 10:32

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  5. Content type: Meeting report

    This paper summarizes the Part 1 of the proceedings of the 8th International Conference on Management and Rehabilitation of Chronic Respiratory Failure, held in Pescara, Italy, on 7 and 8 May, 2015. It summarizes...

    Authors: Nicolino Ambrosino, Richard Casaburi, Alfredo Chetta, Enrico Clini, Claudio F. Donner, Michael Dreher, Roger Goldstein, Amal Jubran, Linda Nici, Caroline A. Owen, Carolyn Rochester, Martin J. Tobin, Guido Vagheggini, Michele Vitacca and Richard ZuWallack

    Citation: Multidisciplinary Respiratory Medicine 2015 10:31

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  6. Content type: Meeting report

    This paper summarizes the Part 2 of the proceedings of the 8th International Conference on Management and Rehabilitation of Chronic Respiratory Failure, held in Pescara, Italy, on 7 and 8 May, 2015. It summarizes...

    Authors: Nicolino Ambrosino, Richard Casaburi, Alfredo Chetta, Enrico Clini, Claudio F. Donner, Michael Dreher, Roger Goldstein, Amal Jubran, Linda Nici, Caroline A. Owen, Carolyn Rochester, Martin J. Tobin, Guido Vagheggini, Michele Vitacca and Richard ZuWallack

    Citation: Multidisciplinary Respiratory Medicine 2015 10:30

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  7. Content type: Meeting report

    This paper summarizes the Part 3 of the proceedings of the 8th International Conference on Management and Rehabilitation of Chronic Respiratory Failure, held in Pescara, Italy, on 7 and 8 May, 2015. It summarizes...

    Authors: Nicolino Ambrosino, Richard Casaburi, Alfredo Chetta, Enrico Clini, Claudio F. Donner, Michael Dreher, Roger Goldstein, Amal Jubran, Linda Nici, Caroline A. Owen, Carolyn Rochester, Martin J. Tobin, Guido Vagheggini, Michele Vitacca and Richard ZuWallack

    Citation: Multidisciplinary Respiratory Medicine 2015 10:29

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  8. Content type: Review

    Venous thromboembolism (VTE) is a common complication of malignancies and epidemiological studies suggest that lung cancer belonged to the group of malignancies with the highest incidence rates of VTE. Risk fa...

    Authors: Carolina Vitale, Maria D’Amato, Paolo Calabrò, Anna Agnese Stanziola, Mauro Mormile and Antonio Molino

    Citation: Multidisciplinary Respiratory Medicine 2015 10:28

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  9. Content type: Original research article

    Polymorphisms in the vitamin D receptor (VDR) gene have been studied in immune-related disorders either as independent contributors or in combination with vitamin D concentration. Vitamin D and VDR have been i...

    Authors: Anna Papadopoulou, Panayiotis Kouis, Nikos Middleton, Ourania Kolokotroni, Themistokles Karpathios, Polyxeni Nicolaidou and Panayiotis K. Yiallouros

    Citation: Multidisciplinary Respiratory Medicine 2015 10:26

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  10. Content type: Original Research Article

    The effectiveness of a homeopathic syrup on cough has been demonstrated in an adult population in a previous double-blind randomized study. The present prospective observational study investigated children aff...

    Authors: Alessandro Zanasi, Salvatore Cazzato, Massimiliano Mazzolini, Carla Maria Sofia Ierna, Marianna Mastroroberto, Elena Nardi and Antonio Maria Morselli-Labate

    Citation: Multidisciplinary Respiratory Medicine 2015 10:25

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  11. Content type: Original research article

    Several comorbidities frequently affect COPD progression. Aim of the study was to assess the prevalence of main comorbidities by gender and disease severity in a cohort of COPD patients referring for the first ti...

    Authors: R. W. Dal Negro, L. Bonadiman and P. Turco

    Citation: Multidisciplinary Respiratory Medicine 2015 10:24

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  12. Content type: Original research article

    The Body Mass Index (BMI) is a widely used parameter to study obesity; however it does not assess the distribution of body adiposity. Ultrasonography is a reliable method of measuring subcutaneous (SAT), visce...

    Authors: Zied Rasslan, Roberto Stirbulov, Roberto Saad Junior, Sergio Tercio Curia, Carlos Alberto da Conceição Lima, Eduardo Araújo Perez, Ezequiel Fernandes Oliveira, Claudio Ferdinando Donner and Luis Vicente Franco Oliveira

    Citation: Multidisciplinary Respiratory Medicine 2015 10:23

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  13. Content type: Original research article

    Involvement of the small airways may be related to increased severity and increased demand for health care services and incurring in high costs, private or for the healthcare system. The hyperinflation consequ...

    Authors: J.F. Castelluccio, R. Stirbulov, E.A. Perez, J.C.M. Oliveira, C.F. Donner, L.V.F. Oliveira and Z. Rasslan

    Citation: Multidisciplinary Respiratory Medicine 2015 10:22

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  14. Content type: Original research article

    Recent studies investigating the health effects of air pollution have proven an existing impact around and below international air quality guidelines and standards. These studies were based on accessible data ...

    Authors: Myriam Mrad Nakhlé, Wehbeh Farah, Nelly Ziade, Maher Abboud, Marie-Louise Coussa-Koniski and Isabella Annesi-Maesano

    Citation: Multidisciplinary Respiratory Medicine 2015 10:21

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  15. Content type: Original research article

    Asthma is a serious chronic inflammatory disease affecting 300 million people worldwide. This aim of this study to investigate the anti-inflammatory and anti-asthmatic effects of Laminaria japonica extract in the...

    Authors: Rongjun Lin, Xiaomei Liu, Yan Meng, Mei Xu and Jianping Guo

    Citation: Multidisciplinary Respiratory Medicine 2015 10:20

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  16. Content type: Original Research Article

    Cough is one of the most common symptoms for which patients seek medical attention from primary care physicians and lung specialists. About 40% of the population at any one time report cough.

    Authors: Alessandro Zanasi, Luigi Lanata, Giovanni Fontana, Federico Saibene, Peter Dicpinigaitis and Francesco De Blasio

    Citation: Multidisciplinary Respiratory Medicine 2015 10:19

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  17. Content type: Review

    Kartagener Syndrome (KS) is a rare autosomal recessive genetic disorder, resulting in a group of clinical manifestations, including bronchiectasis, chronic pansinusitis and situs inversus.

    Authors: Nicola Ciancio, Maria Margherita de Santi, Raffaele Campisi, Laura Amato, Giuseppina Di Martino and Giuseppe Di Maria

    Citation: Multidisciplinary Respiratory Medicine 2015 10:18

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  18. Content type: Original research article

    Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory condition which can lead to comorbidities of variable severity, cognitive dysfunction included. The role of supplemental oxygen in prev...

    Authors: Roberto W Dal Negro, Luca Bonadiman, Fernanda P Bricolo, Silvia Tognella and Paola Turco

    Citation: Multidisciplinary Respiratory Medicine 2015 10:17

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  19. Content type: Original research article

    Horses commonly suffer from chronic respiratory disease and are also used in large animal models of spontaneous or induced airway inflammation. The anti-inflammatory properties of curcumin are largely describe...

    Authors: Charlotte Sandersen, Dorothee Bienzle, Simona Cerri, Thierry Franck, Sandrine Derochette, Philippe Neven, Ange Mouytis-Mickalad and Didier Serteyn

    Citation: Multidisciplinary Respiratory Medicine 2015 10:16

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  20. Content type: Case report

    We herein report a case of invasive candidiasis presenting rare findings on chest computed tomography (CT). The chest CT scan showed multiple small cavitary lesions and nodules with surrounding ground-glass op...

    Authors: Yuichiro Yasuda, Kazunori Tobino, Mina Asaji, Yoshikazu Yamaji and Kosuke Tsuruno

    Citation: Multidisciplinary Respiratory Medicine 2015 10:11

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  21. Content type: Case report

    Bronchial thermoplasty (BT) is a new therapeutic option for severe refractory asthma not controlled despite high dose inhaled corticosteroids plus long-acting bronchodilators and omalizumab in selected cases. ...

    Authors: Nicola Facciolongo, Francesco Menzella, Mirco Lusuardi, Roberto Piro, Carla Galeone, Claudia Castagnetti, Alberto Cavazza, Cristiano Carbonelli, Luigi Zucchi and Pier Paolo Salsi

    Citation: Multidisciplinary Respiratory Medicine 2015 10:9

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  22. Content type: Original research article

    Data for the U.S adult population from the National Health and Nutrition Examination Survey (NHANES) were used to evaluate risk factors for a restrictive pattern on spirometry and estimate the change in its pr...

    Authors: Laura Kurth and Eva Hnizdo

    Citation: Multidisciplinary Respiratory Medicine 2015 10:7

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  23. Content type: State of the art

    Withholding and withdrawing a treatment already established are two forms of limitation of the therapeutic effort (LTE). The question of undergoing or not undergoing lifesaving medical treatments is not restri...

    Authors: Patrizia Borsellino

    Citation: Multidisciplinary Respiratory Medicine 2015 10:5

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  24. Content type: Reviewer acknowledgement

    The editors of Multidisciplinary Respiratory Medicine would like to thank all of our reviewers who have contributed to the journal in Volume 9 (2014).

    Authors: Fernando De Benedetto, Claudio F Donner and Claudio M Sanguinetti

    Citation: Multidisciplinary Respiratory Medicine 2015 10:2

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  25. Content type: Original research article

    Chronic Obstructive Pulmonary Disease (COPD) is characterized by respiratory and extrarespiratory components referring both to systemic complications of COPD, like skeletal muscle myopathy, weight loss and oth...

    Authors: Giorgio Fumagalli, Fabrizio Fabiani, Silvia Forte, Massimiliano Napolitano, Giovanni Balzano, Matteo Bonini, Giuseppe De Simone, Salvatore Fuschillo, Antonella Pentassuglia, Franco Pasqua, Pietro Alimonti, Stefano Carlone and Claudio M Sanguinetti

    Citation: Multidisciplinary Respiratory Medicine 2015 10:4

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  26. Content type: Original research article

    The adequate control of asthma includes the absence of nocturnal symptoms, minimal use of medication, normal or nearly normal lung function and no limitations to physical activity. The choice of a more sedenta...

    Authors: Elisangela Ramos, Luis Vicente Franco de Oliveira, Audrey Borghi Silva, Ivan Peres Costa, João Carlos Ferrari Corrêa, Dirceu Costa, Vera Lucia Alves, Claudio F Donner, Roberto Stirbulov, Ross Arena and Luciana Malosa Sampaio

    Citation: Multidisciplinary Respiratory Medicine 2015 10:3

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  27. Content type: Review

    Patients with severe asthma or COPD have often a suboptimal symptom control due to inadequate treatment. A better understanding of pathogenetic mechanisms, phenotypes, endotypes and the new technologies availa...

    Authors: Francesco Menzella, Mirco Lusuardi, Carla Galeone and Luigi Zucchi

    Citation: Multidisciplinary Respiratory Medicine 2015 10:1

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  28. Content type: Original research article

    Chronic Obstructive Pulmonary Disease (COPD) ranks third as cause of mortality and disability-adjusted life years (DALY) worldwide and also in Italy it imposes a huge health, social and economic load. Early sy...

    Authors: Claudio M Sanguinetti, Nicolino Ambrosino, Filippo Andò, Fernando De Benedetto, Claudio F Donner, Stefano Nardini, Mario Polverino, Roberto Torchio, Guido Vagheggini and Alberto Visconti

    Citation: Multidisciplinary Respiratory Medicine 2014 9:65

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  29. Content type: Review

    Chronic obstructive pulmonary disease (COPD) is a widespread respiratory disorder, usually characterized by progressive and poorly reversible airflow limitation. Inhaled long-acting bronchodilators, namely LAB...

    Authors: Girolamo Pelaia, Rosario Maselli and Luca Gallelli

    Citation: Multidisciplinary Respiratory Medicine 2014 9:64

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  30. Content type: Review

    This article deals with the prevalence and the possible reasons of COPD underestimation in the population and gives suggestions on how to overcome the obstacles and make the correct diagnosis in order to provi...

    Authors: Stefano Carlone, Bruno Balbi, Michela Bezzi, Marco Brunori, Stefano Calabro, Maria Pia Foschino Barbaro, Claudio Micheletto, Salvatore Privitera, Roberto Torchio, Pietro Schino and Andrea Vianello

    Citation: Multidisciplinary Respiratory Medicine 2014 9:63

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  31. Content type: Case report

    Chemical pleurodesis is widely recommended in the treatment of pulmonary air leak of different etiologies as well as malignant pleural effusions and chylothorax. Conventional chemical pleurodesis using erythro...

    Authors: Suk Ju Cho, Su Wan Kim and Jee Won Chang

    Citation: Multidisciplinary Respiratory Medicine 2014 9:61

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  32. Content type: Review

    Adherence to medical therapies is a growing issue, so much so that the World Health Organization defined it as “a new pharmacological problem”. The main factors affecting compliance are: frequency of administr...

    Authors: Alessandro Sanduzzi, Piero Balbo, Piero Candoli, Giousuè A Catapano, Paola Contini, Alessio Mattei, Giovanni Puglisi, Luigi Santoiemma and Anna A Stanziola

    Citation: Multidisciplinary Respiratory Medicine 2014 9:60

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  33. Content type: Original research article

    Acute pneumonia is a serious problem in the elderly and various risk factors have already been reported, but the involvement of QTc interval prolongation remains uncertain. The aim of this study was to elucida...

    Authors: Yasuyuki Taooka, Gen Takezawa, Miki Ohe, Akihisa Sutani and Takeshi Isobe

    Citation: Multidisciplinary Respiratory Medicine 2014 9:59

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  34. Content type: Original research article

    (Buccalin ®) is a Bacterial Lysates (BL) that belongs to a family of immune-stimulators, developed more than 30 years ago and it still has a role in the prophylaxis of Recurrent Respiratory Tract Infections (R...

    Authors: Stefano Carlone, Michele Minenna, Paride Morlino, Luigi Mosca, Franco Pasqua, Riccardo Pela, Pietro Schino, Alberto Tubaldi, Emmanuele Tupputi and Fernando De Benedetto

    Citation: Multidisciplinary Respiratory Medicine 2014 9:58

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  35. Content type: Original research article

    Clinical trials applying iota-carrageenan nasal spray have previously shown to reduce duration of virus-confirmed common cold. The present study pooled data of two similar clinical trials to provide further ev...

    Authors: Martin Koenighofer, Thomas Lion, Angelika Bodenteich, Eva Prieschl-Grassauer, Andreas Grassauer, Hermann Unger, Christian A Mueller and Tamás Fazekas

    Citation: Multidisciplinary Respiratory Medicine 2014 9:57

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  36. Content type: Review

    This review examines some of the issues encountered in the use of sedation in patients receiving respiratory support from non-invasive ventilation (NIV). This is an area of critical and intensive care medicine...

    Authors: Dan Longrois, Giorgio Conti, Jean Mantz, Andreas Faltlhauser, Riku Aantaa and Peter Tonner

    Citation: Multidisciplinary Respiratory Medicine 2014 9:56

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  37. Content type: Case report

    Veno-arterial extracorporeal membrane oxygenation (ECMO) through the femoral vein and artery may cause differential hypoxia, i.e., lower PaO2 in the upper body than in the lower body, because of normal cardiac ou...

    Authors: Joon Hyouk Choi, Su Wan Kim, Young Uck Kim, Song-Yi Kim, Ki-Seok Kim, Seung-Jae Joo and Jung Seok Lee

    Citation: Multidisciplinary Respiratory Medicine 2014 9:55

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  38. Content type: Original research article

    Tracheal occlusion (TO) stimulates lung growth in fetuses affected with congenital diaphragmatic hernia (CDH) although the processes involved in lung maturation still remain unknown. The objective of this stud...

    Authors: Gloria Pelizzo, Maurizio Ballico, Maria Chiara Mimmi, José Louis Peirò, Mario Marotta, Costanzo Federico, Erika Andreatta, Ghassan Nakib, Maurilio Sampaolesi, Elisa Zambaiti and Valeria Calcaterra

    Citation: Multidisciplinary Respiratory Medicine 2014 9:54

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  39. Content type: Original research article

    The management of patients with complex forms of bronchial asthma and COPD is not usually addressed in the major international guidelines and management documents which exclusively address pure forms. AIMAR th...

    Authors: Claudio F Donner and Alberto Visconti

    Citation: Multidisciplinary Respiratory Medicine 2014 9:52

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  40. Content type: Original research article

    Data on exercise pulmonary hemodynamics in healthy people and patients with pulmonary hypertension (PH) are rare. We analyzed exercise right heart catheterization (RHC) data in a symptomatic collective referre...

    Authors: Stephan Keusch, Anina Bucher, Séverine Müller-Mottet, Elisabeth Hasler, Marco Maggiorini, Rudolf Speich and Silvia Ulrich

    Citation: Multidisciplinary Respiratory Medicine 2014 9:51

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