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  1. Content type: Original research article

    It remains unknown whether desaturation profiles during daily living are associated with prognosis in patients with chronic obstructive pulmonary disease (COPD). Point measurements of resting oxygen saturation...

    Authors: Seigo Minami, Suguru Yamamoto, Yoshitaka Ogata, Takeshi Nakatani, Yoshiko Takeuchi, Masanari Hamaguchi, Taro Koba and Kiyoshi Komuta

    Citation: Multidisciplinary Respiratory Medicine 2014 9:24

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  2. Content type: Review

    Increased asthma severity is not only associated with enhanced recurrent hospitalization and mortality but also with higher social costs.

    Authors: Gennaro D’Amato, Anna Stanziola, Alessandro Sanduzzi, Gennaro Liccardi, Antonello Salzillo, Carolina Vitale, Antonio Molino, Alessandro Vatrella and Maria D’Amato

    Citation: Multidisciplinary Respiratory Medicine 2014 9:23

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  3. Content type: Short report

    To evaluate the effect of variation of the Arg16Gly polymorphism of the β2-adrenergic receptor gene on clinical response to salmeterol administered with fluticasone propionate in Chinese Han asthmatic patients.

    Authors: Yuying Qiu, Deping Zhang, Yu Qin and Kai-Sheng Yin

    Citation: Multidisciplinary Respiratory Medicine 2014 9:22

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  4. Content type: Original research article

    The purpose of this study was to evaluate the role of ventilatory parameters in maximal exercise performance in elite soccer players.

    Authors: Adriano Di Paco, Giosuè A Catapano, Guido Vagheggini, Stefano Mazzoleni, Matteo Levi Micheli and Nicolino Ambrosino

    Citation: Multidisciplinary Respiratory Medicine 2014 9:20

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  5. Content type: Original research article

    Vitamin D deficiency has been implicated as a factor in a number of infectious and inflammatory lung diseases. In the lung, alveolar macrophages play a key role in inflammation and defense of infection, but th...

    Authors: Alicia K Gerke, Alejandro A Pezzulo, Fan Tang, Joseph E Cavanaugh, Thomas B Bair, Emily Phillips, Linda S Powers and Martha M Monick

    Citation: Multidisciplinary Respiratory Medicine 2014 9:18

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  6. Content type: Original research article

    Denim sandblasting may cause silicosis as a result of free crystalline silica inhalation. Its pathogenesis remains unclear, but autoimmunity may play a role in the development of silicosis. The present study a...

    Authors: Hasan Dogan, Metin Akgun, Omer Araz, Elif Yilmazel Ucar, Ozgur Yoruk, Eda Diyarbakir, Omer Atis, Fatih Akdemir, Hamit Acemoglu and Ibrahim Pirim

    Citation: Multidisciplinary Respiratory Medicine 2014 9:17

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  7. Content type: Original research article

    COPD is characterized by considerable diversity in terms of clinical signs and symptoms, physiopathological mechanisms, response to treatment and disease progression. For this reason, the identification of dif...

    Authors: Maria Sandra Magnoni, Andrea Rizzi, Alberto Visconti and Claudio F Donner

    Citation: Multidisciplinary Respiratory Medicine 2014 9:16

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  8. Content type: Original research article

    Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality at global level even if still underestimated. The insufficient use of specific tools for an objective definition and sta...

    Authors: Roberto W Dal Negro, Luca Bonadiman and Paola Turco

    Citation: Multidisciplinary Respiratory Medicine 2014 9:15

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  9. Content type: State of the art

    Withholding or withdrawing a life-sustaining treatment tends to be very challenging for health care providers, patients, and their family members alike. When a patient’s life seems to be nearing its end, it is...

    Authors: Jos VM Welie and Henk AMJ ten Have

    Citation: Multidisciplinary Respiratory Medicine 2014 9:14

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  10. Content type: Original research article

    To evaluate and compare the diagnostic efficiency of serum (s) and pleural (p) levels of adenosine deaminase (ADA)-1, ADA-2, total ADA, and interferon-gamma (IFN-γ) for the differential diagnosis of pleural tu...

    Authors: Sibel Yurt, Canan Küçükergin, Burcu Arpinar Yigitbas, Şule Seçkin, Hüseyin Cem Tigin and Ayşe Filiz Koşar

    Citation: Multidisciplinary Respiratory Medicine 2014 9:12

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  11. Content type: Original research article

    The mean platelet volume (MPV) reflects the size of platelets. It has been shown to be inversely correlated with level of the inflammation in some chronic inflammatory diseases. This prospective study aims to ...

    Authors: Gulsah Gunluoglu, Esra Ertan Yazar, Nurdan Simsek Veske, Ekrem Cengiz Seyhan and Sedat Altin

    Citation: Multidisciplinary Respiratory Medicine 2014 9:11

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  12. Content type: Original research article

    Chlamydia psittaci (Cp) is a respiratory pathogen capable of inducing acute pulmonary zoonotic disease (psittacosis) or persistent infection. To elucidate the pathogenesis of this infection, a translational large...

    Authors: Carola Ostermann, Susanna Linde, Christiane Siegling-Vlitakis and Petra Reinhold

    Citation: Multidisciplinary Respiratory Medicine 2014 9:10

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    The Erratum to this article has been published in Multidisciplinary Respiratory Medicine 2014 9:42

  13. Content type: Original research article

    The safety of beta-blockers as a heart rate-limiting drug (HRLD) in patients with acute respiratory failure (ARF) due to chronic obstructive lung disease (COPD) has not been properly assessed in the intensive ...

    Authors: Feyza Kargin, Huriye Berk Takir, Cuneyt Salturk, Nezihe Ciftaslan Goksenoglu, Can Yucel Karabay, Ozlem Yazicioglu Mocin, Nalan Adiguzel, Gokay Gungor, Merih Kalamanoglu Balci, Murat Yalcinsoy, Ramazan Kargin and Zuhal Karakurt

    Citation: Multidisciplinary Respiratory Medicine 2014 9:8

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  14. Content type: Original research article

    Pharmacologic therapies have an important role in the success of interventions for smoking cessation. This study aims to determine the efficacy of several pharmacologic treatments in patients who applied to a ...

    Authors: Elif Yilmazel Ucar, Omer Araz, Nafiye Yilmaz, Metin Akgun, Mehmet Meral, Hasan Kaynar and Leyla Saglam

    Citation: Multidisciplinary Respiratory Medicine 2014 9:9

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  15. Content type: Original research article

    Chronic obstructive pulmonary disease (COPD) is a major cause of acute hospital admissions. The main object of our study was to evaluate the effects of telemedicine video-consultation (TVC) on the frequency of...

    Authors: Safaa Saleh, Jan Petter Larsen, Johannes Bergsåker-Aspøy and Heidi Grundt

    Citation: Multidisciplinary Respiratory Medicine 2014 9:6

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  16. Content type: Reviewer acknowledgement

    The editors of Multidisciplinary Respiratory Medicine would like to thank all of our reviewers who have contributed to the journal in Volume 8 (2013).

    Authors: Fernando De Benedetto, Claudio F Donner and Claudio M Sanguinetti

    Citation: Multidisciplinary Respiratory Medicine 2014 9:4

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  17. Content type: Original research article

    Some peptides, which regulate the metabolic balance, are thought to play important roles in nutritional disorders and systemic inflammation in COPD. Treatment of rats with obestatin decreased body-weight gain....

    Authors: Yi Lei, Yasha Liang, Yifan Chen, Xiaojing Liu, Xiaoyang Liao and Fengming Luo

    Citation: Multidisciplinary Respiratory Medicine 2014 9:5

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  18. Content type: Original research article

    Extravascular lung water (EVLW) is a sensitive prognostic indicator of pulmonary edema. Thus, EVLW may be an advantageous method of fluid management. This study aims to evaluate the outcomes of using EVLW and ...

    Authors: Wei Hu, Chang-Wen Lin, Bing-Wei Liu, Wei-Hang Hu and Ying Zhu

    Citation: Multidisciplinary Respiratory Medicine 2014 9:3

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  19. Content type: Original research article

    The distribution of allergens may vary with different geographic areas, suggesting the importance of local epidemiological data to support evidence-based prevention and management of allergic diseases. We inve...

    Authors: Bao-qing Sun, Pei-yan Zheng, Xiao-wen Zhang, Hui-min Huang, De-hui Chen and Guang-qiao Zeng

    Citation: Multidisciplinary Respiratory Medicine 2014 9:2

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  20. Content type: Original research article

    Aspergillus infection was mostly reported with high mortality rates and a bad prognosis in immunocompromised patients, but data were lacking on the clinical characteristics of aspergillus infection in liver cirrh...

    Authors: Jiajia Chen, Qing Yang, Jianrong Huang and Lanjuan Li

    Citation: Multidisciplinary Respiratory Medicine 2014 9:1

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  21. Content type: Review

    The diagnosis of pulmonary embolism (PE) is frequently considered in patients presenting to the emergency department or when hospitalized. Although early treatment is highly effective, PE is underdiagnosed and...

    Authors: Federico Lavorini, Vitantonio Di Bello, Maria Luisa De Rimini, Giovanni Lucignani, Letizia Marconi, Gualtiero Palareti, Raffaele Pesavento, Domenico Prisco, Massimo Santini, Nicola Sverzellati, Antonio Palla and Massimo Pistolesi

    Citation: Multidisciplinary Respiratory Medicine 2013 8:75

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  22. Content type: Original research article

    Different medical therapies are employed in acute lung injury (ALI) but there is still a debate about the efficacy of these drugs. Among these therapies steroids are clinically applied and bosentan is experime...

    Authors: Omer Araz, Elif Demirci, Elif Yilmazel Ucar, Muhammet Calik, Didem Pulur, Adem Karaman, Muhammed Yayla, Eren Altun, Zekai Halici and Metin Akgun

    Citation: Multidisciplinary Respiratory Medicine 2013 8:74

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  23. Content type: Case report

    It can be difficult to perform CT guided biopsy of small pulmonary nodules especially if the position is behind a costa or close to the diaphragm and respiratory movements may hamper the procedure. During apne...

    Authors: Benedict Kjaergaard, Peter R Zepernick, Annette Bergmann, Henrik K Jensen, Milka Mladenovic and Bodil S Rasmussen

    Citation: Multidisciplinary Respiratory Medicine 2013 8:73

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  24. Content type: Review

    Pulmonary Hypertension (PH) associated to chronic respiratory diseases is currently classified in the 3rd group, as a mild to moderate form of pre-capillary PH that progressively complicates the prognosis of asso...

    Authors: Lucio Casali, Pierluigi Carratù and Matteo Sofia

    Citation: Multidisciplinary Respiratory Medicine 2013 8:72

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  25. Content type: Short report

    Indoor air pollution (IAP) constitutes a major global public health problem requiring increasing efforts in research and policymaking that may have special significance for elderly that are likely to spend mos...

    Authors: Isabella Annesi-Maesano, Dan Norback, Jan Zielinski, Alfred Bernard, Cristina Gratziou, Torben Sigsgaard, Piersante Sestini and Giovanni Viegi

    Citation: Multidisciplinary Respiratory Medicine 2013 8:71

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  26. Content type: Original research article

    Despite the gradual improvement in treatment procedures and cure rates of acromegaly, a steady increase in the mortality rate due to respiratory disease has been documented in recent decades. In this study, ou...

    Authors: Gustavo Bittencourt Camilo, Fernando Silva Guimarães, Débora Pedroza Guedes Silva, Roberto Mogami, Leandro Kasuki, Mônica Roberto Gadelha, Pedro Lopes Melo and Agnaldo José Lopes

    Citation: Multidisciplinary Respiratory Medicine 2013 8:70

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  27. Content type: Original research article

    Non-small cell lung cancer (NSCLC) accounts for approximately 80% of new diagnoses of pulmonary carcinoma. This study investigated the correlation between 18 F-fluorodeoxyglucose uptake in computerized tomogra...

    Authors: Mehmet Akif Özgül, Gamze Kirkil, Ekrem Cengiz Seyhan, Erdoğan Çetinkaya, Güler Özgül and Mahmut Yüksel

    Citation: Multidisciplinary Respiratory Medicine 2013 8:69

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  28. Content type: Original research article

    Guidelines advise annual influenza vaccination in chronic asthma. The aim of this study was to determine uptake of the influenza vaccine in a group of patients (n = 146) with moderate to severe chronic asthma ...

    Authors: Rachelle Asciak, Martin Balzan and Jesmar Buttigieg

    Citation: Multidisciplinary Respiratory Medicine 2013 8:68

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  29. Content type: Commentary

    Oxytocin (Sintocynon) is considered an uncommon cause of severe allergic reactions during delivery. We have recently shown that allergic sensitization to latex might constitute an important predisposing risk f...

    Authors: Gennaro Liccardi, Maria Beatrice Bilò, Ciro Mauro, Antonello Salzillo, Amedeo Piccolo, Maria D’Amato, Annabella Liccardi and Gennaro D’Amato

    Citation: Multidisciplinary Respiratory Medicine 2013 8:67

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  30. Content type: Original research article

    The prevalence of sexual dysfunction in patients with COPD is high and its significance has not been sufficiently stressed. The aim of this study is to investigate the incidence of erectile dysfunction (ED) an...

    Authors: Hasan Kahraman, Bilal Sen, Nurhan Koksal, Metin Kilinç and Sefa Resim

    Citation: Multidisciplinary Respiratory Medicine 2013 8:66

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  31. Content type: Original research article

    Lung cancer is the leading cause of death among cancers in the world. The annual death toll due to this disease exceeds the combined deaths caused by colon, breast, prostate, and pancreatic cancers. As a resul...

    Authors: Feridoun Karimi-Busheri, Aghdass Rasouli-Nia, Victoria Zadorozhny and Habib Fakhrai

    Citation: Multidisciplinary Respiratory Medicine 2013 8:65

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  32. Content type: Original research article

    Frequent exacerbations of chronic obstructive pulmonary disease (COPD) have negative effects on quality of life and survival. Thus, factors related to exacerbations should be determined. We aimed to evaluate t...

    Authors: Sevinc Sarinc Ulasli, Serife Savas Bozbas, Zeynep Erayman Ozen, Berna Akinci Ozyurek and Gaye Ulubay

    Citation: Multidisciplinary Respiratory Medicine 2013 8:64

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  33. Content type: Original research article

    The purpose of the study was to determine the relationship between high sensitivity C-reactive protein (hs-CRP) levels and prognostic factors in chronic obstructive pulmonary disease.

    Authors: Reshu Agarwal, Mohammad Shoaib Zaheer, Zubair Ahmad and Jamal Akhtar

    Citation: Multidisciplinary Respiratory Medicine 2013 8:63

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  34. Content type: Original research article

    Appetite-modulating hormones ghrelin and leptin might be relevant to asthma with their pro-inflammatory effects, and calprotectin has been recognized as a promising marker of inflammation. The purpose of this ...

    Authors: Nazan Cobanoglu, Nilufer Galip, Ceyhun Dalkan and Nerin Nadir Bahceciler

    Citation: Multidisciplinary Respiratory Medicine 2013 8:62

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  35. Content type: Original research article

    The aim of this study is to investigate the prevalence of metabolic syndrome (MetS), carotid intima media thickness (IMT), and serum C-reactive protein (CRP) levels in patients with chronic obstructive pulmona...

    Authors: Aylin Ozgen Alpaydin, Isin Konyar Arslan, Selim Serter, Aysin Sakar Coskun, Pinar Celik, Fatma Taneli and Arzu Yorgancioglu

    Citation: Multidisciplinary Respiratory Medicine 2013 8:61

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  36. Content type: Original research article

    Literature is still arguing about a possible relationship between airway hyperresponsiveness (AHR) and body mass index (BMI). This study aimed at evaluating the influence of BMI on AHR and pulmonary function i...

    Authors: Bruno Sposato, Marco Scalese, Maria Giovanna Migliorini, Maria Piera Riccardi, Massimo Tosti Balducci, Luigi Petruzzelli and Raffaele Scala

    Citation: Multidisciplinary Respiratory Medicine 2013 8:60

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  37. Content type: Original research article

    Invasive pulmonary aspergillosis (IPA) is an infection often occurring in neutropenic patients and has high mortality rates. In recent years, it has been reported that the incidence of IPA has also increased i...

    Authors: Nuri Tutar, Gokhan Metan, Ayşe Nedret Koç, Insu Yilmaz, Ilkay Bozkurt, Zuhal Ozer Simsek, Hakan Buyukoglan, Asiye Kanbay, Fatma Sema Oymak, Inci Gulmez and Ramazan Demir

    Citation: Multidisciplinary Respiratory Medicine 2013 8:59

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  38. Content type: Original research article

    Cardiovascular disease (CVD) is a common comorbidity in patients with chronic airway obstruction, and is associated with systemic inflammation and airway obstruction. The aim of this study was to evaluate the ...

    Authors: Michela Bellocchia, Monica Masoero, Antonio Ciuffreda, Silvia Croce, Arianna Vaudano, Roberto Torchio, Monica Boita and Caterina Bucca

    Citation: Multidisciplinary Respiratory Medicine 2013 8:58

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  39. Content type: Commentary

    Valid sarcoidosis incidence assessment is contingent on access to medical care, thoroughness of reportage, assiduity of radiographic interpretation, employment and health care screening policies, misclassifica...

    Authors: Jerome M Reich

    Citation: Multidisciplinary Respiratory Medicine 2013 8:57

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  40. Content type: Original research article

    Incidental thyroid nodules (ITNs) are defined as newly encountered nodules identified on imaging performed for an unrelated purpose. In practice, ITNs are often detected on chest computed tomography (CT). We i...

    Authors: Jong Hoo Lee, Sun Young Jeong and Yee Hyung Kim

    Citation: Multidisciplinary Respiratory Medicine 2013 8:56

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  41. Content type: Review

    Chest ultrasonography can be a useful diagnostic tool for respiratory physicians. It can be used to complete and widen the general objective examination also in emergency situations, at the patient’s bedside. ...

    Authors: Andrea Smargiassi, Riccardo Inchingolo, Gino Soldati, Roberto Copetti, Giampietro Marchetti, Alessandro Zanforlin, Rosangela Giannuzzi, Americo Testa, Stefano Nardini and Salvatore Valente

    Citation: Multidisciplinary Respiratory Medicine 2013 8:55

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  42. Content type: Review

    Chest ultrasonography can be a useful diagnostic tool for respiratory physicians. It can be used to complete and widen the general objective examination also in emergency situations, at the patient’s bedside. ...

    Authors: Alessandro Zanforlin, Rosangela Giannuzzi, Stefano Nardini, Americo Testa, Gino Soldati, Roberto Copetti, Giampietro Marchetti, Salvatore Valente, Riccardo Inchingolo and Andrea Smargiassi

    Citation: Multidisciplinary Respiratory Medicine 2013 8:54

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  43. Content type: Review

    Idiopathic pulmonary fibrosis (IPF), a chronic fibrosing lung disease of a progressive nature and unknown etiology, has the largest epidemiological impact and the worst prognosis among the idiopathic interstit...

    Authors: Gaetano Cicchitto and Claudio M Sanguinetti

    Citation: Multidisciplinary Respiratory Medicine 2013 8:53

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  44. Content type: Original research article

    Mount Etna, located in the eastern part of Sicily (Italy), is the highest and most active volcano in Europe. During the sustained eruption that occurred in October-November 2002 huge amounts of volcanic ash fe...

    Authors: Daniele Lombardo, Nicola Ciancio, Raffaele Campisi, Annalisa Di Maria, Laura Bivona, Venerino Poletti, Antonio Mistretta, Annibale Biggeri and Giuseppe Di Maria

    Citation: Multidisciplinary Respiratory Medicine 2013 8:51

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  45. Content type: Review

    Asthma is considered an heterogeneous disease, requiring multiple biomarkers for diagnosis and management. Fractional exhaled nitric oxide in exhaled breath (FeNO) was the first useful non-invasive marker of a...

    Authors: Giuliana Ferrante, Velia Malizia, Roberta Antona, Giovanni Corsello and Stefania La Grutta

    Citation: Multidisciplinary Respiratory Medicine 2013 8:50

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