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  1. Tracheal surgery requires a highly specialized team of anesthesiologists, thoracic surgeons, and operative support staff. It remain a formidable challenge for surgeons due to the criticality connected to anato...

    Authors: Alessandra Siciliani, Erino Angelo Rendina and Mohsen Ibrahim
    Citation: Multidisciplinary Respiratory Medicine 2018 13:34
  2. Hemoptysis is a frequent sign of respiratory and non-respiratory diseases. While in most cases the underlying cause is rapidly identified, sometimes the real etiology might be misdiagnosed with dramatic delay ...

    Authors: Matteo Fontana, Roberto Tonelli, Filippo Gozzi, Ivana Castaniere, Alessandro Marchioni, Riccardo Fantini, Francesca Coppi, Filippo Natali, Elisabetta Rovatti and Enrico Clini
    Citation: Multidisciplinary Respiratory Medicine 2018 13:25
  3. Acute respiratory failure can be triggered by several causes, either of pulmonary or extra-pulmonary origin. Pompe disease, or type II glycogen storage disease, is a serious and often fatal disorder, due to a ...

    Authors: Francesco Menzella, Luca Codeluppi, Mirco Lusuardi, Carla Galeone, Franco Valzania and Nicola Facciolongo
    Citation: Multidisciplinary Respiratory Medicine 2018 13:32
  4. A substantial increase in pulmonary and extra-pulmonary diseases due to non-tuberculous mycobacteria (NTM) has been documented worldwide, especially among subjects suffering from chronic respiratory diseases a...

    Authors: Stefano Aliberti, Luigi Ruffo Codecasa, Andrea Gori, Giovanni Sotgiu, Maura Spotti, Antonio Di Biagio, Andrea Calcagno, Stefano Nardini, Baroukh Maurice Assael, Enrico Tortoli, Giorgio Besozzi, Maurizio Ferrarese, Alberto Matteelli, Enrico Girardi, Saverio De Lorenzo, Manuela Seia…
    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):33

    This article is part of a Supplement: Volume 13 Supplement 1

  5. Determining the effects of antimicrobial therapies on airway microbiology at a population-level is essential. Such analysis allows, for example, surveillance of antibiotic-induced changes in pathogen prevalenc...

    Authors: Steven L. Taylor, Lex E. X. Leong, Fredrick M. Mobegi, Jocelyn M. Choo, Lucy D. Burr, Steve Wesselingh and Geraint B. Rogers
    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):30

    This article is part of a Supplement: Volume 13 Supplement 1

  6. Bronchiectasis is the final result of different processes and most of the guidelines advocate for a careful evaluation of those etiologies which might be treated or might change patients’ management, including...

    Authors: Andrea Gramegna, Stefano Aliberti, Manuela Seia, Luigi Porcaro, Vera Bianchi, Carlo Castellani, Paola Melotti, Claudio Sorio, Enza Consalvo, Elisa Franceschi, Francesco Amati, Martina Contarini, Michele Gaffuri, Luca Roncoroni, Barbara Vigone, Angela Bellofiore…
    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):29

    This article is part of a Supplement: Volume 13 Supplement 1

  7. Bronchiectasis represents the final pathway of several infectious, genetic, immunologic or allergic disorders. Accurate and prompt identification of the underlying cause is a key recommendation of several inte...

    Authors: Martina Contarini, Amelia Shoemark, Jessica Rademacher, Simon Finch, Andrea Gramegna, Michele Gaffuri, Luca Roncoroni, Manuela Seia, Felix C. Ringshausen, Tobias Welte, Francesco Blasi, Stefano Aliberti and James D. Chalmers
    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):26

    This article is part of a Supplement: Volume 13 Supplement 1

  8. The contemporary diagnosis of bronchiectasis requires CT scanning to describe specific structural lung changes. Scoring systems have been designed and validated in some specific causes of bronchiectasis to all...

    Authors: Philip Robinson and Lucy Morgan
    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):24

    This article is part of a Supplement: Volume 13 Supplement 1

  9. Double aortic arch is a rare congenital and complete vascular ring around trachea and esophagus. It is usually diagnosed during infancy. The symptoms are generally related to respiratory and gastroesophageal t...

    Authors: Davide Piloni, Claudio Tirelli, Rita Di Domenica, Valentina Conio, Amelia Grosso, Vanessa Ronzoni, Filippo Antonacci, Pasquale Totaro and Angelo G. Corsico
    Citation: Multidisciplinary Respiratory Medicine 2018 13:21
  10. Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis, mainly associated with work or environmental exposure to asbestos. MPM’s molecular profile is largerly unexplored and effective ...

    Authors: Matteo Bosio, Elena Salvaterra, Francesca Datturi, Patrizia Morbini, Michele Zorzetto, Simona Inghilleri, Stefano Tomaselli, Patrizia Mangiarotti, Federica Meloni, Isa Cerveri and Giulia Maria Stella
    Citation: Multidisciplinary Respiratory Medicine 2018 13:27
  11. Understanding positive and negative influences on adult immunization status can help healthcare providers to better identify and target patients who are likely to need immunization. Our aim was to assess and c...

    Authors: Stephanie Attard Camilleri, Juanita Camilleri Casingena, Kentaro Yamagata and Martin Balzan
    Citation: Multidisciplinary Respiratory Medicine 2018 13:23
  12. After publication of the Original research article [1] it was brought to our attention that the sentence at pag 6 (between Figure 3 and Figure 4)) must be corrected as follows: “The mean duration of inactivity...

    Authors: Roberto W. Dal Negro, Luca Bonadiman and Paola Turco
    Citation: Multidisciplinary Respiratory Medicine 2018 13:31

    The original article was published in Multidisciplinary Respiratory Medicine 2018 13:18

  13. Despite advances with regard to “do not attempt resuscitation order”, physicians are still reluctant to implement it. In fact, while the nurses could be of great help in making decision about “do not attempt r...

    Authors: Masoud Fallahi, Somaye Mahdavikian, Alireza Abdi, Fariba Borhani, Parvin Taghizadeh and Behzad Hematpoor
    Citation: Multidisciplinary Respiratory Medicine 2018 13:20
  14. This paper summarizes the presentations submitted for publication of the 12th AIST National Congress (Associazione Italiana Studio Tosse/Italian Association for Cough Study) entitled “The thousand facets of cough...

    Authors: Alessandro Zanasi, Antonio M. Morselli-Labate, Massimiliano Mazzolini, Marianna Mastroroberto, Roberto W. Dal Negro, Ivan Poliacek, Alyn H. Morice, Sara Maio, Giovanni Viegi, Jamie Koufman, Francesco Torresan, Alexandros Ioannou, Daniele Mandolesi, Elisa Liverani, Amedeo Montale, Franco Bazzoli…
    Citation: Multidisciplinary Respiratory Medicine 2018 13:17
  15. Bronchial asthma is an inflammatory disease of the airways. Beclomethasone dipropionate/Formoterol (BDP/F) and Fluticasone furoate/Vilanterol (FF/V) are two of the most effective LABA/ICS combinations for mana...

    Authors: Roberto W. Dal Negro, Luca Bonadiman and Paola Turco
    Citation: Multidisciplinary Respiratory Medicine 2018 13:18

    The Correction to this article has been published in Multidisciplinary Respiratory Medicine 2018 13:31

  16. Recently, it is reported that Actinomyces meyeri is the most common species causing actinomycosis. However, to our knowledge, there was no report about pulmonary actinomycosis attributable to A. meyeri presenting...

    Authors: Saori Nishizawa, Keisuke Anan, Kazunori Tobino, Masanobu Okahisa, Yuki Goto, Kojin Murakami, Takuto Sueyasu, Miyuki Munechika, Kohei Yoshimine and Mai Yoshino
    Citation: Multidisciplinary Respiratory Medicine 2018 13:19
  17. The drug pirfenidone has been shown to slow the progression and decrease mortality of idiopathic pulmonary fibrosis (IPF). Its exact mechanism is unknown, but it likely inhibits pro-fibrotic cytokine transform...

    Authors: Amber Mortensen, Lauren Cherrier and Rajat Walia
    Citation: Multidisciplinary Respiratory Medicine 2018 13:16
  18. Outdoor air pollution is a major threat to global public health that needs responsible participation of researchers at all levels. Assessing research output is an important step in highlighting national and in...

    Authors: Waleed M. Sweileh, Samah W. Al-Jabi, Sa’ed H. Zyoud and Ansam F. Sawalha
    Citation: Multidisciplinary Respiratory Medicine 2018 13:15
  19. Idiopathic pulmonary fibrosis (IPF) is characterized by progressive loss of lung function with high mortality within the first 5 years from diagnosis. In 2011–2014, two drugs, pirfenidone and nintedanib, have ...

    Authors: Ida Pesonen, Lisa Carlson, Nicola Murgia, Riitta Kaarteenaho, Carl Magnus Sköld, Marjukka Myllärniemi and Giovanni Ferrara
    Citation: Multidisciplinary Respiratory Medicine 2018 13:14
  20. Medical air (MA) is widely used in hospitals, often manufactured onsite by compressing external ambient air and supplied through a local network piping system. Onsite production gives rise to a risk of impurit...

    Authors: Paul Edwards, Patricia-Ann Therriault and Ira Katz
    Citation: Multidisciplinary Respiratory Medicine 2018 13:12
  21. People with Chronic Obstructive Pulmonary Disease (COPD) suffer from dyspnoea, which may be increased by anxiety. Previous studies suggest that relaxation techniques may have positive effects in pulmonary reha...

    Authors: Eleonora Volpato, Paolo Banfi, Antonello Nicolini and Francesco Pagnini
    Citation: Multidisciplinary Respiratory Medicine 2018 13:13
  22. Chronic airway inflammation and hypersensitivity to bacterial infection may contribute to lung cancer pathogenesis. Previous studies have demonstrated that nontypeable Haemophilus influenzae (NTHi) is the most co...

    Authors: Krishna B. Sriram, Amanda J. Cox, Pathmanathan Sivakumaran, Maninder Singh, Annabelle M. Watts, Nicholas P. West and Allan W. Cripps
    Citation: Multidisciplinary Respiratory Medicine 2018 13:11
  23. Tuberculosis (TB) is a major global health problem, commonly seen in underdeveloped countries. The probability of contracting the disease is significantly higher among the economically vulnerable and the socia...

    Authors: Madapathage Gayan Buddhika Senanayake, Sumudu Indika Wickramasinghe, Sudath Samaraweera, Pubudu De Silva and Sisira Edirippulige
    Citation: Multidisciplinary Respiratory Medicine 2018 13:9
  24. Tuberculosis (TB) remains the most common cause of infectious disease deaths worldwide. What is perhaps less appreciated is that the caseload of tuberculosis patients in South Asia is staggering.

    Authors: Buddha Basnyat, Maxine Caws and Zarir Udwadia
    Citation: Multidisciplinary Respiratory Medicine 2018 13:10
  25. The progressive increase in the elderly population contributes to the fact that studies on human aging have important attention of health professionals and government agents, since they present a great challen...

    Authors: Glauber Sá Brandão, Fernanda Warken Rosa Camelier, Antônia Adonis Callou Sampaio, Glaudson Sá Brandão, Anderson Soares Silva, Glaucia Sá Brandão Freitas Gomes, Claudio F. Donner, Luis Vicente Franco Oliveira and Aquiles Assunção Camelier
    Citation: Multidisciplinary Respiratory Medicine 2018 13:8
  26. Influenza and influenza-like syndromes (I-LSs) are infectious diseases occurring on a seasonal basis which can lead to upper (URTI) and lower respiratory tract illness (LRTI) of different severity. The approac...

    Authors: Roberto W. Dal Negro, Alessandro Zanasi, Paola Turco and Massimiliano Povero
    Citation: Multidisciplinary Respiratory Medicine 2018 13:7
  27. We aimed to assess recent Latin American medical school graduates’ knowledge and attitudes about OSA and examine whether their knowledge and attitudes about OSA differed from practicing physicians.

    Authors: Iván Chérrez-Ojeda, Juan Carlos Calderón, Andrea Fernández García, Donna B. Jeffe, Ilka Santoro, Emanuel Vanegas, Annia Cherrez, José Cano, Freddy Betancourt and Daniel Simancas-Racines
    Citation: Multidisciplinary Respiratory Medicine 2018 13:5
  28. Aging causes physiological changes which affect the quality of sleep. Supervised physical exercise is an important therapeutic resource to improve the sleep of the elderlies, however there is a low adherence t...

    Authors: Glauber Sá Brandão, Glaucia Sá Brandão Freitas Gomes, Glaudson Sá Brandão, Antônia A. Callou Sampaio, Claudio F. Donner, Luis V. F. Oliveira and Aquiles Assunção Camelier
    Citation: Multidisciplinary Respiratory Medicine 2018 13:2
  29. Spirometry is the single most important test for the evaluation of respiratory function. The results are interpreted by comparing measured data with predicted values previously obtained from a reference popula...

    Authors: Joana Belo, Teresa Palmeiro, Iolanda Caires, Ana L. Papoila, Marta Alves, Pedro Carreiro-Martins, Maria A. Botelho and Nuno Neuparth
    Citation: Multidisciplinary Respiratory Medicine 2018 13:4
  30. The aim of this paper was to evaluate the availability of FRAX for assessing osteoporosis risk, and to demonstrate the importance of vitamin D levels in COPD patients.

    Authors: Ceyda Anar, Melike Yüksel Yavuz, Filiz Güldaval, Yelda Varol and Dilek Kalenci
    Citation: Multidisciplinary Respiratory Medicine 2018 13:1
  31. Guaifenesin, a mucoactive drug, acts by loosening mucus in the airways and making coughs more productive. It is used for relief of wet cough and chest congestion due to the common cold, and remains the only le...

    Authors: Helmut H. Albrecht, Peter V. Dicpinigaitis and Eric P. Guenin
    Citation: Multidisciplinary Respiratory Medicine 2017 12:31
  32. Tobacco use and the Western diet are two of the most important and investigated topics in relation to adolescents’ health. In addition, air pollution is a crucial subject for future generations. School is a ke...

    Authors: Chiara Marabelli, Elena Munarini, Micaela Lina, Roberto Mazza, Roberto Boffi, Cinzia De Marco, Ario Ruprecht, Giorgia Angellotti, Chiara Veronese, Paolo Pozzi, Eleonora Bruno, Giuliana Gargano, Adalberto Cavalleri, Giulia Garrone and Franco Berrino
    Citation: Multidisciplinary Respiratory Medicine 2017 12:30
  33. Non-communicable diseases (NCDs) kill 40 million people each year. The management of chronic respiratory NCDs such as chronic obstructive pulmonary disease (COPD) is particularly critical in Italy, where they ...

    Authors: Stefano Nardini, Fernando De Benedetto, Claudio M. Sanguinetti, Salvatore Bellofiore, Stefano Carlone, Salvatore Privitera, Luciano Sagliocca and Emmanuele Tupputi
    Citation: Multidisciplinary Respiratory Medicine 2017 12:28
  34. Chronic (non-communicable) diseases (NCD) -- principally cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes -- are leading causes of death and disability. There is the need to adopt a ...

    Authors: Giovanni Viegi, Stefano Centanni and Francesco Blasi
    Citation: Multidisciplinary Respiratory Medicine 2017 12:27
  35. Alpha-1-antitrypsin deficiency (AATD) is an under-diagnosed condition in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to screen for AATD in Kazakh patients with COPD us...

    Authors: Ardak Zhumagaliyeva, Stefania Ottaviani, Timm Greulich, Marina Gorrini, Claus Vogelmeier, Ludmila Karazhanova, Gulmira Nurgazina, Annalisa DeSilvestri, Victor Kotke, Valentina Barzon, Michele Zorzetto, Angelo Corsico and Ilaria Ferrarotti
    Citation: Multidisciplinary Respiratory Medicine 2017 12:23
  36. Community-acquired pneumonia is a common and serious disease, with high rates of morbidity and mortality. Management and treatment of community-acquired pneumonia are described in three main documents: the 200...

    Authors: Marco Mantero, Paolo Tarsia, Andrea Gramegna, Sonia Henchi, Nicolò Vanoni and Marta Di Pasquale
    Citation: Multidisciplinary Respiratory Medicine 2017 12:26
  37. Chronic lymphocytic leukemia (CLL) is the most frequent lymphoproliferative disease. Transformation into Richter disease and occurrence of second malignancies involving the lungs are rare complications. The ha...

    Authors: Ghassen Soussi, Selsabil Daboussi, Samira Mhamdi, Zied Moatemri, Hela Ghedira, Chiraz Aichaouia, Mohsen Khadhraoui, Faouzi El Mezni and Rezaik Cheikh
    Citation: Multidisciplinary Respiratory Medicine 2017 12:24
  38. Small airways are considered the major site of airflow limitation in COPD. Impulse oscillometry (IOS) is a forced oscillation technique, which provides passive measurement of lung mechanics. It can differentia...

    Authors: Antonio Molino, Francesca Simioli, Anna Agnese Stanziola, Mauro Mormile, Maria Martino and Maria D’Amato
    Citation: Multidisciplinary Respiratory Medicine 2017 12:25
  39. Desmoplastic small round cell tumor of the pleura is a rare malignancy, with only a few cases reported in the scientific literature. The aim of the present review is to discuss the demographic, pathological, c...

    Authors: Alessandro Giuseppe Fois, Pietro Pirina, Antonella Arcadu, Francesca Becciu, Sandra Manca, Viviana Marras, Sara Canu, Gaetano Castagna, Giorgio Carlo Ginesu, Angelo Zinellu and Panagiotis Paliogiannis
    Citation: Multidisciplinary Respiratory Medicine 2017 12:22
  40. Although nasal polyps are one of the most frequent diseases, their etiopathogenesis remains unclear.Since eosinophils are the main inflammatory cells in the substantial proportion of nasal polyp tissues, they ...

    Authors: Figen Aslan, Eren Altun, Serpil Paksoy and Gulay Turan
    Citation: Multidisciplinary Respiratory Medicine 2017 12:21
  41. COPD is one of the leading causes of morbidity and mortality. Pharmacotherapy improves quality of life and reduces exacerbations although low adherence with prescribed treatments may represent a barrier to opt...

    Authors: G. De Filippi, M. Lallini, G. De Riggi, G. Marchetti, C. M. Dimartino, A. M. Russetti, E. Ferrari, R. Pistelli, M. S. Magnoni, M. Riparbelli, A. Rizzi and P. Angeletti
    Citation: Multidisciplinary Respiratory Medicine 2017 12:18
  42. Precision medicine promises to improve prognosis of patients affected by untreatable diseases. Patients with lung cancer (especially lung adenocarcinoma) bear an increased risk of VTE. Mutations in the EGFR an...

    Authors: Elsa Davidsson, Nicola Murgia, Cristian Ortiz-Villalón, Emil Wiklundh, Magnus Sköld, Karl Gustav Kölbeck and Giovanni Ferrara
    Citation: Multidisciplinary Respiratory Medicine 2017 12:16
  43. Medical approach to patients is a fundamental step to get the correct diagnosis. The aim of this paper is to analyze some aspects of the reasoning process inherent in medical diagnosis in our era. Pathologic s...

    Authors: Gino Soldati, Andrea Smargiassi, Alberto A. Mariani and Riccardo Inchingolo
    Citation: Multidisciplinary Respiratory Medicine 2017 12:15