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Table 2 Smoking cessation therapy (Modified from MC Fiore, 2008)

From: The clinical and integrated management of COPD. An official document of AIMAR (Interdisciplinary Association for Research in Lung Disease), AIPO (Italian Association of Hospital Pulmonologists), SIMER (Italian Society of Respiratory Medicine), SIMG (Italian Society of General Medicine)

Type of intervention

Odds ratio (95% C.I.)

Abstinence rate (95% C.I.)

Cognitive-behavioural treatment

None

1.0

10.9

Minimal advice (<3 min)

1.3 (1.01-1.06)

13.4 (10.9-16.1)

Counseling 3–10 min

1.6 (1.2-2.0)

16.0 (12.8-19.2)

Counseling > 10 min

2.3 (2.0-2.7)

22.1 (19.4-24.7)

Pharmacologic therapy

Placebo

1.0

13.8

Varenicline

3.1

33.2 (28.9-37.8)

Nicotine replacement therapy (NRT)

  

Patch (6–14 weeks)

1.9 (1.7-2.2)

23.4 (21.3-25.8)

Chewing gum (6–14 weeks)

1.5 (1.2-1.7)

19.0 (16.5- 21.9)

Inhaler

2.1 (1.5-2.9)

24.8 (19.1-31.6)

SR Bupropion

2.0 (1.8-2.2)

24.2 (22.1-26.4)