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  1. Letter to the Editor

    Once daily aerosolised tobramycin in adult patients with cystic fibrosis in the management of Pseudomonas aeruginosa chronic infection

    It is estimated that about 60–70% of Cystic Fibrosis patients develop Pseudomonas aeruginosa chronic infection, with progressive loss of lung function, as well as increased antibiotic resistance and mortality.

    Marco Mantero, Andrea Gramegna, Giovanna Pizzamiglio, Alice D’Adda, Paolo Tarsia and Francesco Blasi

    Multidisciplinary Respiratory Medicine 2017 12:2

    Published on: 7 February 2017

  2. Original research article

    Pulmonary arterial hypertension associated with interferon therapy: a population-based study

    Isolated cases of pulmonary arterial hypertension (PAH) with interferon α or β therapy have been reported, but no population-based estimates of the incidence of the disease after interferon exposure are availa...

    Ravikanth Papani, Alexander G. Duarte, Yu-li Lin, Yong-Fang Kuo and Gulshan Sharma

    Multidisciplinary Respiratory Medicine 2017 12:1

    Published on: 17 January 2017

  3. Original research article

    Bibliometric analysis of worldwide publications on multi-, extensively, and totally drug – resistant tuberculosis (2006–2015)

    The year 2015 marked the end of United Nations Millennium Development Goals which was aimed at halting and reversing worldwide tuberculosis (TB). The emergence of drug resistance is a major challenge for world...

    Waleed M. Sweileh, Adham S. AbuTaha, Ansam F. Sawalha, Suleiman Al-Khalil, Samah W. Al-Jabi and Sa’ed H. Zyoud

    Multidisciplinary Respiratory Medicine 2017 11:45

    Published on: 11 January 2017

  4. Original research article

    Cost of persistent asthma in Italy

    Asthma is a common disease of the airways with a significant burden for the society and for patients’ quality of life. The Social Impact of Respiratory Integrated Outcomes (SIRIO) study estimated a mean cost o...

    Roberto W. Dal Negro, Chiara Distante, Luca Bonadiman, Paola Turco and Sergio Iannazzo

    Multidisciplinary Respiratory Medicine 2016 11:44

    Published on: 16 December 2016

  5. Original research article

    DNA damage and repair capacity in lymphocyte of chronic obstructive pulmonary diseases patients during physical exercise with oxygen supplementation

    We hypothesized that the use of oxygen supplementation during aerobic exercise induces less DNA damage than exercise alone.

    Andréa Lúcia Gonçalves da Silva, Thaís Evelyn Karnopp, Augusto Ferreira Weber, Cassia da Luz Goulart, Paloma de Borba Scheneiders, Dannuey Machado Cardoso, Lisiane Lisboa Carvalho, Joel Henrique Ellwanger, Lia Gonçalves Possuelo and Andréia Rosane de Moura Valim

    Multidisciplinary Respiratory Medicine 2016 11:43

    Published on: 14 December 2016

  6. Original research article

    Personality and unachieved treatment goals related to poor adherence to asthma medication in a newly developed adherence questionnaire – a population-based study

    Health-care professionals have a responsibility to be attentive to patients’ adherence behavior but it could be difficult to identify poor adherence in the context of clinical practice. Assessment of personali...

    Malin Axelsson, Linda Ekerljung, Bo Lundbäck and Jan Lötvall

    Multidisciplinary Respiratory Medicine 2016 11:42

    Published on: 5 December 2016

  7. Original research article

    Hemothorax following lung transplantation: incidence, risk factors, and effect on morbidity and mortality

    Hemothorax after lung transplantation may result in increased post-operative morbidity and mortality. Risk factors for developing hemothorax and the outcomes of patients who develop hemothorax have not been we...

    Aria Hong, Christopher S. King, A. Whitney Walter Brown, Shahzad Ahmad, Oksana A. Shlobin, Sandeep Khandhar, Linda Bogar, Anthony Rongione and Steven D. Nathan

    Multidisciplinary Respiratory Medicine 2016 11:40

    Published on: 15 November 2016

  8. Original research article

    Respiratory illness and air pollution from the steel industry: the case of Piquiá de Baixo, Brazil (Preliminary report)

    This report is based on an independent study carried out by medical professionals of the Fondazione IRCCS Istituto Nazionale dei Tumori (National Cancer Institute) in Milan, Italy, and  aimed to assess the inc...

    Carla Valenti, Paolo Pozzi, Alessandra Busia, Roberto Mazza, Paolo Bossi, Cinzia De Marco, Ario Alberto Ruprecht, Alessandro Borgini and Roberto Boffi

    Multidisciplinary Respiratory Medicine 2016 11:41

    Published on: 9 November 2016

  9. Original research article

    Efficacy of recombinant human soluble thrombomodulin for the treatment of acute exacerbation of idiopathic pulmonary fibrosis: a single arm, non-randomized prospective clinical trial

    Coagulation abnormalities are involved in the pathogenesis of acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF). The administration of recombinant human soluble thrombomodulin (rhTM), which has bot...

    Sho Hayakawa, Yasuo Matsuzawa, Tamako Irie, Hagino Rikitake, Noriaki Okada and Yasuo Suzuki

    Multidisciplinary Respiratory Medicine 2016 11:38

    Published on: 7 November 2016

  10. Letter to the Editor

    Cost comparison of asthma treatments in 12-week study: caution about matching and short observational follow-up

    In the absence of randomisation, observational studies must take extra care to create treatment groups that are comparable in terms of key characteristics. Various matching methods exist which can create sound...

    David B. Price, Job F. M. van Boven, Lisa M. Law, Alessandra Cifra and R. Brett McQueen

    Multidisciplinary Respiratory Medicine 2016 11:39

    Published on: 2 November 2016

  11. Review

    Asthma-related deaths

    Despite major advances in the treatment of asthma and the development of several asthma guidelines, people still die of asthma currently. According to WHO estimates, approximately 250,000 people die prematurel...

    Gennaro D’Amato, Carolina Vitale, Antonio Molino, Anna Stanziola, Alessandro Sanduzzi, Alessandro Vatrella, Mauro Mormile, Maurizia Lanza, Giovanna Calabrese, Leonardo Antonicelli and Maria D’Amato

    Multidisciplinary Respiratory Medicine 2016 11:37

    Published on: 12 October 2016

  12. Original research article

    The effect of positive airway pressure therapy on neurocognitive functions, depression and anxiety in obesity hypoventilation syndrome

    The aim of this study is to evaluate the presence of neurocognitive dysfunctions, depression and anxiety and the effect of positive airway pressure (PAP) therapy on these alterations in Obesity Hypoventilation...

    Serap Argun Baris, Dilek Tuncel, Cigdem Ozerdem, Huseyin Kutlu, Tugba Onyilmaz, Ilknur Basyigit, Hasim Boyaci and Fusun Yildiz

    Multidisciplinary Respiratory Medicine 2016 11:35

    Published on: 11 October 2016

  13. Original research article

    Preliminary study on the assessment of visceral adipose tissue using dual-energy x-ray absorptiometry in chronic obstructive pulmonary disease

    Visceral adipose tissue (VAT) was shown to be increased in patients with chronic obstructive pulmonary disease (COPD) compared to control subjects with comparable body mass index (BMI). Our aim was to determin...

    Francesca De Blasio, Erica P. A. Rutten, Emiel F. M. Wouters, Luca Scalfi, Francesco De Blasio, Marco A. Akkermans, Martijn A. Spruit and Frits M. E. Franssen

    Multidisciplinary Respiratory Medicine 2016 11:33

    Published on: 4 October 2016

  14. Original research article

    Cough: impact, beliefs, and expectations from a national survey

    Cough is one of the most common discomforts affecting general population, which can disrupt subjects’ quality of life due to its physical, social, and psychological effects. Aim of the study was to investigate...

    Roberto W. Dal Negro, Massimiliano Mazzolini, Paola Turco and Alessandro Zanasi

    Multidisciplinary Respiratory Medicine 2016 11:34

    Published on: 27 September 2016

  15. Original research article

    Cultural and linguistic validation of the NHQ-2 Questionnaire: a specific instrument for assessing patient’s usability of inhalation devices

    An increasing number of inhalation devices are presently available in the market. They are differently characterized in terms of their handling and usability, both factors which may affect the outcomes of resp...

    Roberto W. Dal Negro and Massimiliano Povero

    Multidisciplinary Respiratory Medicine 2016 11:32

    Published on: 23 August 2016

  16. Review

    Obesity: systemic and pulmonary complications, biochemical abnormalities, and impairment of lung function

    Obesity is currently one of the major epidemics of this millennium and affects individuals throughout the world. It causes multiple systemic complications, some of which result in severe impairment of organs a...

    Thiago Thomaz Mafort, Rogério Rufino, Cláudia Henrique Costa and Agnaldo José Lopes

    Multidisciplinary Respiratory Medicine 2016 11:28

    Published on: 12 July 2016

  17. Original research article

    Most Italians attending a congress on health of elderly people do not know and do not recognize respiratory diseases

    The present study reports the results of a survey jointly carried out by three Italian respiratory scientific associations (AIMAR, AIPO, SIMeR) together with an important Federation of elderly patients (FederA...

    Nicola Ciancio, Claudio M. Sanguinetti, Franco Falcone, Claudio Taranto, Roberto Fasani, Fernando De Benedetto, Onofrio Resta, Fausto De Michele, Roberto Messina, Andrea Rossi, Stefano Nardini and Giuseppe Di Maria

    Multidisciplinary Respiratory Medicine 2016 11:26

    Published on: 5 July 2016

  18. Original research article

    High bacterial load of indoor air in hospital wards: the case of University of Gondar teaching hospital, Northwest Ethiopia

    The air inhaled by people is abundantly populated with microorganisms which also are called bioaerosols. Bioaerosols is a colloidal suspension, formed by liquid droplets and particles of solid matter in the ai...

    Zemichael Gizaw, Mulat Gebrehiwot and Chalachew Yenew

    Multidisciplinary Respiratory Medicine 2016 11:24

    Published on: 5 July 2016

  19. Case report

    Sarcoidosis with prevalent and severe joint localization: a case report

    Sarcoidosis is a systemic granulomatous disease of unknown origin, characterized by the formation of granulomas without central necrosis. Each organ and tissue can be affected by the disease, but in most cases...

    Livio G. Moccia, Sabrina Castaldo, Emanuela Sirignano, Maddalena Napolitano, Enrica Barra and Alessandro Sanduzzi

    Multidisciplinary Respiratory Medicine 2016 11:27

    Published on: 29 June 2016

  20. Original research article

    Evaluation of the rapid immunochromatographic ODK0501 assay for Streptococcus pneumoniae antigen detection with nasopharyngeal swabs: preliminary report

    Early identification and control of pathogenic bacteria are important in the treatment of pneumonia. Currently, two rapid antigen detection kits for pneumococcal pneumonia are available: one uses urine samples...

    Shoji Suzuki, Naoki Nishimura, Torahiko Jinta, Yasuhiko Yamano, Genta Ishikawa, Yutaka Tomishima, Noboru Uchiyama and Naohiko Chohnabayashi

    Multidisciplinary Respiratory Medicine 2016 11:25

    Published on: 20 June 2016

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