Published on: 22 May 2017
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Published on: 22 May 2017
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Published on: 18 May 2017
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The official journal of the Italian Respiratory Society - Società Italiana di Pneumologia (IRS/SIP)
Multidisciplinary Respiratory Medicine is the official journal of the Italian Respiratory Society - Società Italiana di Pneumologia (IRS/SIP). The journal publishes on all aspects of respiratory medicine and related fields, with a particular focus on interdisciplinary and translational research.
The interdisciplinary nature of the journal provides a unique opportunity for researchers, clinicians and healthcare professionals across specialties to collaborate and exchange information. The journal provides a high visibility platform for the publication and dissemination of top quality original scientific articles, reviews and important position papers documenting clinical and experimental advances.
Given the journal’s interdisciplinary character, the target readership is wider than respiratory medicine, embracing numerous related disciplines (allergology, immunology, internal medicine, geriatrics, infectious diseases, intensive care, etc) and health professionals.
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Pulmonary drug delivery is currently the focus of accelerated research and development because of the potential to produce maximum therapeutic benefit to patients by directly targeting drug to the site of pathology in the lungs. Among the available delivery options, the dry powder inhaler (DPI) is the preferred device for the treatment of an increasingly diverse range of diseases. This article reviews recent advances in capsule-based DPI technology and the introduction of the ‘disposable’ DPI device.
The intratracheal instillation of bleomycin in mice induces early damage to alveolar epithelial cells and development of inflammation followed by fibrotic tissue changes. Histopathology is the gold standard for assessing lung fibrosis in rodents, however it precludes repeated and longitudinal measurements of disease progression. This study investigates the use of the Micro-CT technique to allow the evaluation of disease onset and progression at different time-points in the mouse bleomycin model of lung fibrosis.