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Table 1 Act Scores, Pulmonary Function and Inflammatory Parameters of the Study Patients at the Baseline and Follow Up Visits

From: Does asthma control as assessed by the asthma control test reflect airway inflammation?Il controllo dell’asma valutato con l’“asthma control test” rispecchia l’infiammazione delle vie aeree?

 

Baseline (n = 83)

3rd month (n = 83)

p*

ACT score (mean ± SD)

18.98 ± 4.59

19.65 ± 4.11

0.164

Control of asthma, n (%)

  

0.779

   Totally controlled

8 (10)

10 (12)

 

   Partially controlled

36 (43)

39 (47)

 

   Uncontrolled

39 (47)

34 (41)

 

FEV1 (L) (mean ± SD)

2.59 ± 0.62

2.65 ± 0.60

0.162

FEV1 (%) (mean ± SD)

93.9 ± 13.7

93.0 ± 15.8

0.968

FEV1/FVC (%) (mean ± SD)

78.2 ± 6.9

77.7 ± 7.1

0.387

MBPT positivity, n (%)

49 (59)

37 (45)

0.029

FeNO (ppb), median (1st and 3rd quartiles)

15 (11-26)

14 (11-21)

0.025

Elevated induced sputum eosinophil (> 3%), n (%)

11/47 (23)

9/30 (30%)

0.791

Induced sputum neutrophil (%), median (1st and 3rd quartiles)

32 (11-50)

34 (18-56)

0.241

  1. Definition of abbreviations: ACT, asthma control test; FeNO, exhaled nitric oxide; FEV1, forced expiratory volume in 1 sec; FVC, forced vital capacity; MBPT, methacholine bronchial provocation test.
  2. *Significant p values (less than 0.05) are emphasized with bold font.