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  1. Sensitization to inhaled allergens in children with bronchial asthma significantly affects asthma pathogenesis, severity and persistence into late childhood and adulthood. The present study determined the prev...

    Authors: Enas M Al-Zayadneh, Nedal Awad Alnawaiseh, Areej Hamed Altarawneh, Ibrahim Hamed Aldmour, Eman M. Albataineh, Hani Al-Shagahin, Abdelrahman Alharazneh and Ebaa Alzayadneh

    Citation: Multidisciplinary Respiratory Medicine 2019 14:37

    Content type: Original research article

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  2. Little is known about how patients and healthcare providers (HCPs) perceive the impact of asthma-related exacerbations. This study examined the impact of asthma-related exacerbations on patients’ lives from th...

    Authors: Phaedra T. Johnson, Christopher F. Bell, John White, Breanna Essoi, Linda Nelsen and Carlyne M. Averell

    Citation: Multidisciplinary Respiratory Medicine 2019 14:32

    Content type: Original research article

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  3. Usefulness of Pidotimod and its role as immunostimulant, has been discussed, we know, for several decades. Nevertheless, there is still much to know. Understanding its mechanisms and its potential usefulness i...

    Authors: Francesca Puggioni, Magna Alves-Correia, Manar-Farouk Mohamed, Niccolò Stomeo, Riccardo Mager, Massimiliano Marinoni, Francesca Racca, Giovanni Paoletti, Gilda Varricchi, Veronica Giorgis, Giovanni Melioli, Giorgio Walter Canonica and Enrico Heffler

    Citation: Multidisciplinary Respiratory Medicine 2019 14:31

    Content type: Review

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  4. A frequent treatment recommendation during acute respiratory infection is to increase fluid intake. This is the first study to investigate whether upper respiratory tract infections (URTIs) such as common cold...

    Authors: Ronald Eccles and Pascal Mallefet

    Citation: Multidisciplinary Respiratory Medicine 2019 14:36

    Content type: Original research article

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  5. Few investigations have related objective assessments of indoor air pollutants to respiratory health in farmers, in spite of the many rural environmental hazards to which they are exposed. Chemical air polluti...

    Authors: Cara Nichole Maesano, Denis Caillaud, Hassani Youssouf, Soutrik Banerjee, Julie Prud’Homme, Christelle Audi, Kigninlman Horo, Yacouba Toloba, Ollivier Ramousse and Isabella Annesi-Maesano

    Citation: Multidisciplinary Respiratory Medicine 2019 14:33

    Content type: Original research article

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  6. Cystic fibrosis (CF) is a genetic disease caused by a defect of CF transmembrane conductance regulator (CFTR) gene. CF affects multiple systems, predominantly with respiratory involvement. In Qatar, researcher...

    Authors: Samer Hammoudeh, Wessam Gadelhak, Atqah AbdulWahab, Mona Al-Langawi and Ibrahim A. Janahi

    Citation: Multidisciplinary Respiratory Medicine 2019 14:29

    Content type: Review

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  7. Inhalation devices affect both the effectiveness and the therapeutic outcomes in persistent airway obstruction, and the effects are largely independent of the drug(s) assumed. Usability is a complex and compre...

    Authors: Roberto W. Dal Negro, Paola Turco and Massimiliano Povero

    Citation: Multidisciplinary Respiratory Medicine 2019 14:30

    Content type: Original research article

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  8. The role of primary care physician in COPD management varies in different health care systems. According to the researches in various countries, extent of spirometry use in diagnosing and grading COPD frequent...

    Authors: Greta Ragaišienė, Rūta Kibarskytė, Rasa Gauronskaitė, Monika Giedraitytė, Agnė Dapšauskaitė, Vytautas Kasiulevičius and Edvardas Danila

    Citation: Multidisciplinary Respiratory Medicine 2019 14:28

    Content type: Original research article

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  9. In this project the authors use a narrative medicine (NM) approach to assess the promotion of trust in the relationship between physicians and their asthma patients.

    Authors: Antonietta Cappuccio, Silvia Napolitano, Francesco Menzella, Guido Pellegrini, Alessandro Policreti, Girolamo Pelaia, Pasquale Alberto Porpiglia and Maria Giulia Marini

    Citation: Multidisciplinary Respiratory Medicine 2019 14:26

    Content type: Original research article

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  10. Work-related respiratory diseases (WRDs) account for 10–20% of all chronic respiratory illnesses affecting hundreds of millions of people of all ages. Tannery industries are often associated with hazardous wor...

    Authors: Innawu Dalju, Awrajaw Dessie, Laekemariame Bogale and Tesfaye Hambisa Mekonnen

    Citation: Multidisciplinary Respiratory Medicine 2019 14:27

    Content type: Original research article

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  11. Oral methylxanthines are effective drugs for the treatment of chronic obstructive respiratory disorders. The novel methylxanthine doxofylline, that has bronchodilator and anti-inflammatory activities, is not a...

    Authors: Paola Rogliani, Luigino Calzetta, Josuel Ora, Mario Cazzola and Maria Gabriella Matera

    Citation: Multidisciplinary Respiratory Medicine 2019 14:25

    Content type: Original research article

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  12. Although previous studies showed an increasing prevalence of infections due to multi-drug resistant (MDR) bacteria in the community, specific data on sepsis are lacking. We aimed to assess prevalence, risk fac...

    Authors: Nicolò Capsoni, Pietro Bellone, Stefano Aliberti, Giovanni Sotgiu, Donatella Pavanello, Benedetto Visintin, Elena Callisto, Laura Saderi, Davide Soldini, Luca Lardera, Valter Monzani and Anna Maria Brambilla

    Citation: Multidisciplinary Respiratory Medicine 2019 14:23

    Content type: Original research article

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  13. Obstructive sleep apnea (OSA) is a worldwide highly prevalent disease associated with systemic consequences, including excessive sleepiness, impairment of neurocognitive function and daytime performance, inclu...

    Authors: Marta Marin-Oto, Eugenio E. Vicente and Jose M. Marin

    Citation: Multidisciplinary Respiratory Medicine 2019 14:21

    Content type: Review

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  14. It has been hypothesized that changes in lung function can occur in patients with diabetes. Nevertheless, it is unclear how much of this correlation links with biomarkers of metabolism disorder. We have invest...

    Authors: Morteza A. Khafaie, Sundeep S. Salvi, Chittaranjan S. Yajnik, Fakher Rahim and Behzad Khafaei

    Citation: Multidisciplinary Respiratory Medicine 2019 14:22

    Content type: Original research article

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  15. The ventilatory anaerobic threshold (VO2@AT) has been used in preoperative risk assessment and rehabilitation for many years. Our aim was to determine the interobserver variability of AT using cardiopulmonary exe...

    Authors: Sabine Kaczmarek, Dirk Habedank, Anne Obst, Marcus Dörr, Henry Völzke, Sven Gläser and Ralf Ewert

    Citation: Multidisciplinary Respiratory Medicine 2019 14:20

    Content type: Original research article

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  16. We describe the case of a 75 years old patient with a history of hepatocellular carcinoma, with acute respiratory failure due to tracheal obstruction by metastasis, successfully treated with airway disobstruct...

    Authors: Giacomo Ghinassi, Pasquale Imitazione, Alfonso Pecoraro, Luciano B. G. Montella, Paola Martucci, Raffaella Giacobbe, Campione Severo and Domenico Aronne

    Citation: Multidisciplinary Respiratory Medicine 2019 14:19

    Content type: Case report

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  17. Connective Tissue Diseases (CTDs) are systemic autoimmune conditions characterized by frequent lung involvement. This usually takes the form of Interstitial Lung Disease (ILD), but Obstructive Lung Disease (OL...

    Authors: Nicola Ciancio, Mauro Pavone, Sebastiano Emanuele Torrisi, Ada Vancheri, Domenico Sambataro, Stefano Palmucci, Carlo Vancheri, Fabiano Di Marco and Gianluca Sambataro

    Citation: Multidisciplinary Respiratory Medicine 2019 14:17

    Content type: Review

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  18. Bronchoscopy is frequently used to sample the lower airways in lung microbiome studies. Despite being a safe procedure, it is associated with discomfort that may result in reservations regarding participation ...

    Authors: Einar M. H. Martinsen, Tomas M. L. Eagan, Elise O. Leiten, Eli Nordeide, Per S. Bakke, Sverre Lehmann and Rune Nielsen

    Citation: Multidisciplinary Respiratory Medicine 2019 14:14

    Content type: Original research article

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  19. Excessive inhalation of aluminium powder occasionally results in upper lobe predominant lung fibrosis, which is similar to idiopathic pleuroparenchymal fibroelastosis (IPPFE) and has been suggested to be secon...

    Authors: Yuki Yabuuchi, Hitomi Goto, Mizu Nonaka, Hiroaki Tachi, Tatsuya Akiyama, Naoki Arai, Hiroaki Ishikawa, Kentaro Hyodo, Kenji Nemoto, Yukiko Miura, Isano Hase, Shuji Oh-ishi, Kenji Hayashihara, Takefumi Saito and Tatsuya Chonan

    Citation: Multidisciplinary Respiratory Medicine 2019 14:15

    Content type: Case report

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  20. Lung biopsy in asthmatic patients is justified in case of atypical presentations of asthma, when other differential diagnoses, such as hypersensitivity pneumonitis or eosinophilic granulomatosis with polyangii...

    Authors: Sara Colella, Claudia Ravaglia, Chiara Massaccesi, Vittorio D’Emilio, Gianluca Panella, Federica Fioretti, Emanuele Giovanni Conte, Guido Collina, Riccardo Pela and Venerino Poletti

    Citation: Multidisciplinary Respiratory Medicine 2019 14:12

    Content type: Original research article

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  21. Respiratory viral and atypical bacterial infections data in Egyptian patients are sparse. This study describes the clinical features and outcomes of patients with severe acute respiratory infections (SARI) in ...

    Authors: Ashraf Hatem, Sherif Mohamed, Usama E. Abu Elhassan, Eman A. M. Ismael, Magda S. Rizk, Amany El-kholy and Mohamed El-Harras

    Citation: Multidisciplinary Respiratory Medicine 2019 14:11

    Content type: Original research article

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  22. Extrinsic allergic alveolitis (EAA) patients form heterogenous group with different clinical manifestation and different prognosis. We aimed to determine how to phenotype distinct EAA subgroups. Predictive rol...

    Authors: Martina Sterclova, Magdalena Smetakova, Ludek Stehlik, Jelena Skibova and Martina Vasakova

    Citation: Multidisciplinary Respiratory Medicine 2019 14:13

    Content type: Original research article

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  23. The upward shift of hilar structures is a characteristic finding on chest radiographs in pleuroparenchymal fibroelastosis (PPFE). However, the relationship between the hilar shift and clinical parameters is un...

    Authors: Hiroshi Ishii, Yoshiaki Kinoshita, Hisako Kushima, Takashi Ogura and Kentaro Watanabe

    Citation: Multidisciplinary Respiratory Medicine 2019 14:10

    Content type: Short report

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  24. Chest Ultrasonography (chest US) has shown good sensibility in detecting pneumothorax, pleural effusions and peripheral consolidations and it can be performed bedside.

    Authors: Andrea Smargiassi, Riccardo Inchingolo, Marco Chiappetta, Leonardo Petracca Ciavarella, Stefania Lopatriello, Giuseppe Maria Corbo, Stefano Margaritora and Luca Richeldi

    Citation: Multidisciplinary Respiratory Medicine 2019 14:9

    Content type: Original research article

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  25. Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged recently, and new conditio...

    Authors: Maria R. Bonsignore, Pierpaolo Baiamonte, Emilia Mazzuca, Alessandra Castrogiovanni and Oreste Marrone

    Citation: Multidisciplinary Respiratory Medicine 2019 14:8

    Content type: Review

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  26. Prognostic evaluation in idiopathic pulmonary fibrosis (IPF) may be important as it can guide management decisions, but the potential role of honeycomb changes in providing information about outcome and surviv...

    Authors: Claudia Ravaglia, Marcello Bosi, Athol U. Wells, Carlo Gurioli, Christian Gurioli, Alessandra Dubini, Sara Piciucchi, Silvia Puglisi, Susanna Mascetti, Antonella Arcadu, Sara Tomassetti and Venerino Poletti

    Citation: Multidisciplinary Respiratory Medicine 2019 14:3

    Content type: Original research article

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  27. The Swiss COPD cohort was established in 2006 to collect data in a primary care setting. The objective of this study was to evaluate possible predictive factors for exacerbation and re-exacerbation.

    Authors: Pascal Urwyler, Nebal Abu Hussein, Pierre O. Bridevaux, Prashant N. Chhajed, Thomas Geiser, Peter Grendelmeier, Ladina Joos Zellweger, Malcolm Kohler, Sabrina Maier, David Miedinger, Michael Tamm, Robert Thurnheer, Thomas Dieterle and Joerg D. Leuppi

    Citation: Multidisciplinary Respiratory Medicine 2019 14:7

    Content type: Original research article

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  28. The analysis of microbiome in respiratory samples is a topic of great interest in chronic respiratory diseases. The method used to prepare sputum samples for microbiome analysis is very heterogeneous. The sele...

    Authors: Martina Oriano, Leonardo Terranova, Antonio Teri, Samantha Sottotetti, Luca Ruggiero, Camilla Tafuro, Paola Marchisio, Andrea Gramegna, Francesco Amati, Fabrizio Nava, Elisa Franceschi, Lisa Cariani, Francesco Blasi and Stefano Aliberti

    Citation: Multidisciplinary Respiratory Medicine 2019 14:6

    Content type: Original research article

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  29. Non-invasive ventilation (NIV) is the treatment of choice for patients symptomatic for respiratory muscle dysfunction. It can normalize gas exchange and provide up to continuous non-invasive ventilator support...

    Authors: Paolo I. Banfi, Eleonora Volpato and John R. Bach

    Citation: Multidisciplinary Respiratory Medicine 2019 14:4

    Content type: Case report

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  30. Poor indoor air quality is a great problem in schools due to a high number of students per classroom, insufficient outside air supply, poor construction and maintenance of school buildings. Bacteria in the ind...

    Authors: Zewudu Andualem, Zemichael Gizaw, Laekemariam Bogale and Henok Dagne

    Citation: Multidisciplinary Respiratory Medicine 2019 14:2

    Content type: Original research article

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  31. Some previous works have tested LUS use in diagnosing and monitoring interstitial lung diseases. B-lines are main sonographic signs for interstitial diseases. Increasing evidences suggest that dyspnea and impa...

    Authors: Andrea Boccatonda, Valentina Decorato, Giulio Cocco, Stefano Marinari and Cosima Schiavone

    Citation: Multidisciplinary Respiratory Medicine 2018 14:1

    Content type: Original research article

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  32. Obstructive Sleep Apnoea (OSA) is a common sleep disorder that is associated with daytime symptoms and a range of comorbidity and mortality. Continuous Positive Airway Pressure (CPAP) therapy is highly efficac...

    Authors: Kate Sutherland, Kristina Kairaitis, Brendon J. Yee and Peter A. Cistulli

    Citation: Multidisciplinary Respiratory Medicine 2018 13:44

    Content type: Review

    Published on:

  33. The assessment of Idiopathic Pulmonary Fibrosis (IPF) using HRCT requires great experience and is limited by a significant inter-observer variability, even between trained radiologists. The evaluation of HRCT ...

    Authors: Sebastiano Emanuele Torrisi, Stefano Palmucci, Alessandro Stefano, Giorgio Russo, Alfredo Gaetano Torcitto, Daniele Falsaperla, Mauro Gioè, Mauro Pavone, Ada Vancheri, Gianluca Sambataro, Domenico Sambataro, Letizia Antonella Mauro, Emanuele Grassedonio, Antonio Basile and Carlo Vancheri

    Citation: Multidisciplinary Respiratory Medicine 2018 13:43

    Content type: Original research article

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  34. Since 2013 StopTB Italia Onlus supports the Senegalese National Tuberculosis Programme by improving diagnostic capability with technological interventions, ameliorating educational programs for health care per...

    Authors: Mama Moussa Diaw, Mamoudou Ndiaye, Niccolò Riccardi, Riccardo Ungaro, Riccardo Alagna, Daniela Maria Cirillo, Luigi Codecasa, Claudio Viscoli, Laura Ambra Nicolini and Giorgio Besozzi

    Citation: Multidisciplinary Respiratory Medicine 2018 13:41

    Content type: Original research article

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  35. Fifteen years after its licensure, this revision assesses the role of cefditoren facing the current pharmacoepidemiology of resistances in respiratory human-adapted pathogens (Streptococcus pneumoniae, Streptococ...

    Authors: María-José Giménez, Lorenzo Aguilar and Juan José Granizo

    Citation: Multidisciplinary Respiratory Medicine 2018 13:40

    Content type: Review

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  36. Chronic obstructive pulmonary disease (COPD) is associated with high clinical and economic burden. Optimal pharmacological therapy for COPD aims to reduce symptoms and the frequency and severity of exacerbatio...

    Authors: Ami R. Buikema, Lee Brekke, Amy Anderson, Eleena Koep, Damon Van Voorhis, Lucie Sharpsten, Beth Hahn, Riju Ray and Richard H. Stanford

    Citation: Multidisciplinary Respiratory Medicine 2018 13:38

    Content type: Original research article

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  37. The European Respiratory Society recently published an important statement reviewing available evidence on diagnosis and treatment of lung disease associated to alpha-1 antitrypsin deficiency (AATD). Several i...

    Authors: Andrea Gramegna, Stefano Aliberti, Marco Confalonieri, Angelo Corsico, Luca Richeldi, Carlo Vancheri and Francesco Blasi

    Citation: Multidisciplinary Respiratory Medicine 2018 13:39

    Content type: Commentary

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  38. No studies have addressed the impact of lung cancer (LC) on prognosis of patients with idiopathic pulmonary fibrosis (IPF) in Upper Egypt. We aimed to evaluate the prevalence and risk factors for LC among IPF ...

    Authors: Sherif Mohamed, Hassan Bayoumi, Nashwa Abd El-Aziz, Ehab Mousa and Yasser Gamal

    Citation: Multidisciplinary Respiratory Medicine 2018 13:37

    Content type: Original research article

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  39. Patients with chronic obstructive pulmonary disease (COPD) may experience an acute worsening of respiratory symptoms that results in additional therapy; this event is defined as a COPD exacerbation (AECOPD). H...

    Authors: Ernesto Crisafulli, Enric Barbeta, Antonella Ielpo and Antoni Torres

    Citation: Multidisciplinary Respiratory Medicine 2018 13:36

    Content type: Review

    Published on:

  40. Chronic obstructive pulmonary disease (COPD) is a common comorbidity of heart failure (HF), but remains often undiagnosed, and we aimed to identify symptoms predicting COPD in HF. As part of an observational, ...

    Authors: Sara Roversi, Piera Boschetto, Bianca Beghe’, Michela Schito, Martina Garofalo, Mariarita Stendardo, Valentina Ruggieri, Roberto Tonelli, Alessandro Fucili, Roberto D’Amico, Federico Banchelli, Leonardo M. Fabbri and Enrico M. Clini

    Citation: Multidisciplinary Respiratory Medicine 2018 13:35

    Content type: Short report

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  41. Tracheal surgery requires a highly specialized team of anesthesiologists, thoracic surgeons, and operative support staff. It remain a formidable challenge for surgeons due to the criticality connected to anato...

    Authors: Alessandra Siciliani, Erino Angelo Rendina and Mohsen Ibrahim

    Citation: Multidisciplinary Respiratory Medicine 2018 13:34

    Content type: Review

    Published on:

  42. Hemoptysis is a frequent sign of respiratory and non-respiratory diseases. While in most cases the underlying cause is rapidly identified, sometimes the real etiology might be misdiagnosed with dramatic delay ...

    Authors: Matteo Fontana, Roberto Tonelli, Filippo Gozzi, Ivana Castaniere, Alessandro Marchioni, Riccardo Fantini, Francesca Coppi, Filippo Natali, Elisabetta Rovatti and Enrico Clini

    Citation: Multidisciplinary Respiratory Medicine 2018 13:25

    Content type: Case report

    Published on:

  43. Acute respiratory failure can be triggered by several causes, either of pulmonary or extra-pulmonary origin. Pompe disease, or type II glycogen storage disease, is a serious and often fatal disorder, due to a ...

    Authors: Francesco Menzella, Luca Codeluppi, Mirco Lusuardi, Carla Galeone, Franco Valzania and Nicola Facciolongo

    Citation: Multidisciplinary Respiratory Medicine 2018 13:32

    Content type: Case report

    Published on:

  44. A substantial increase in pulmonary and extra-pulmonary diseases due to non-tuberculous mycobacteria (NTM) has been documented worldwide, especially among subjects suffering from chronic respiratory diseases a...

    Authors: Stefano Aliberti, Luigi Ruffo Codecasa, Andrea Gori, Giovanni Sotgiu, Maura Spotti, Antonio Di Biagio, Andrea Calcagno, Stefano Nardini, Baroukh Maurice Assael, Enrico Tortoli, Giorgio Besozzi, Maurizio Ferrarese, Alberto Matteelli, Enrico Girardi, Saverio De Lorenzo, Manuela Seia…

    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):33

    Content type: Original Research Article

    Published on:

    This article is part of a Supplement: Volume 13 Supplement 1

  45. Bronchiectasis is the final result of different processes and most of the guidelines advocate for a careful evaluation of those etiologies which might be treated or might change patients’ management, including...

    Authors: Andrea Gramegna, Stefano Aliberti, Manuela Seia, Luigi Porcaro, Vera Bianchi, Carlo Castellani, Paola Melotti, Claudio Sorio, Enza Consalvo, Elisa Franceschi, Francesco Amati, Martina Contarini, Michele Gaffuri, Luca Roncoroni, Barbara Vigone, Angela Bellofiore…

    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):29

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 13 Supplement 1

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