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  1. Content type: Review

    Connective Tissue Diseases (CTDs) are systemic autoimmune conditions characterized by frequent lung involvement. This usually takes the form of Interstitial Lung Disease (ILD), but Obstructive Lung Disease (OL...

    Authors: Nicola Ciancio, Mauro Pavone, Sebastiano Emanuele Torrisi, Ada Vancheri, Domenico Sambataro, Stefano Palmucci, Carlo Vancheri, Fabiano Di Marco and Gianluca Sambataro

    Citation: Multidisciplinary Respiratory Medicine 2019 14:17

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  2. Content type: Original research article

    Bronchoscopy is frequently used to sample the lower airways in lung microbiome studies. Despite being a safe procedure, it is associated with discomfort that may result in reservations regarding participation ...

    Authors: Einar M. H. Martinsen, Tomas M. L. Eagan, Elise O. Leiten, Eli Nordeide, Per S. Bakke, Sverre Lehmann and Rune Nielsen

    Citation: Multidisciplinary Respiratory Medicine 2019 14:14

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  3. Content type: Case report

    Excessive inhalation of aluminium powder occasionally results in upper lobe predominant lung fibrosis, which is similar to idiopathic pleuroparenchymal fibroelastosis (IPPFE) and has been suggested to be secon...

    Authors: Yuki Yabuuchi, Hitomi Goto, Mizu Nonaka, Hiroaki Tachi, Tatsuya Akiyama, Naoki Arai, Hiroaki Ishikawa, Kentaro Hyodo, Kenji Nemoto, Yukiko Miura, Isano Hase, Shuji Oh-ishi, Kenji Hayashihara, Takefumi Saito and Tatsuya Chonan

    Citation: Multidisciplinary Respiratory Medicine 2019 14:15

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  4. Content type: Original research article

    Lung biopsy in asthmatic patients is justified in case of atypical presentations of asthma, when other differential diagnoses, such as hypersensitivity pneumonitis or eosinophilic granulomatosis with polyangii...

    Authors: Sara Colella, Claudia Ravaglia, Chiara Massaccesi, Vittorio D’Emilio, Gianluca Panella, Federica Fioretti, Emanuele Giovanni Conte, Guido Collina, Riccardo Pela and Venerino Poletti

    Citation: Multidisciplinary Respiratory Medicine 2019 14:12

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  5. Content type: Original research article

    Respiratory viral and atypical bacterial infections data in Egyptian patients are sparse. This study describes the clinical features and outcomes of patients with severe acute respiratory infections (SARI) in ...

    Authors: Ashraf Hatem, Sherif Mohamed, Usama E. Abu Elhassan, Eman A. M. Ismael, Magda S. Rizk, Amany El-kholy and Mohamed El-Harras

    Citation: Multidisciplinary Respiratory Medicine 2019 14:11

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  6. Content type: Original research article

    Extrinsic allergic alveolitis (EAA) patients form heterogenous group with different clinical manifestation and different prognosis. We aimed to determine how to phenotype distinct EAA subgroups. Predictive rol...

    Authors: Martina Sterclova, Magdalena Smetakova, Ludek Stehlik, Jelena Skibova and Martina Vasakova

    Citation: Multidisciplinary Respiratory Medicine 2019 14:13

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  7. Content type: Short report

    The upward shift of hilar structures is a characteristic finding on chest radiographs in pleuroparenchymal fibroelastosis (PPFE). However, the relationship between the hilar shift and clinical parameters is un...

    Authors: Hiroshi Ishii, Yoshiaki Kinoshita, Hisako Kushima, Takashi Ogura and Kentaro Watanabe

    Citation: Multidisciplinary Respiratory Medicine 2019 14:10

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  8. Content type: Original research article

    Chest Ultrasonography (chest US) has shown good sensibility in detecting pneumothorax, pleural effusions and peripheral consolidations and it can be performed bedside.

    Authors: Andrea Smargiassi, Riccardo Inchingolo, Marco Chiappetta, Leonardo Petracca Ciavarella, Stefania Lopatriello, Giuseppe Maria Corbo, Stefano Margaritora and Luca Richeldi

    Citation: Multidisciplinary Respiratory Medicine 2019 14:9

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  9. Content type: Review

    Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged recently, and new conditio...

    Authors: Maria R. Bonsignore, Pierpaolo Baiamonte, Emilia Mazzuca, Alessandra Castrogiovanni and Oreste Marrone

    Citation: Multidisciplinary Respiratory Medicine 2019 14:8

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  10. Content type: Original research article

    Prognostic evaluation in idiopathic pulmonary fibrosis (IPF) may be important as it can guide management decisions, but the potential role of honeycomb changes in providing information about outcome and surviv...

    Authors: Claudia Ravaglia, Marcello Bosi, Athol U. Wells, Carlo Gurioli, Christian Gurioli, Alessandra Dubini, Sara Piciucchi, Silvia Puglisi, Susanna Mascetti, Antonella Arcadu, Sara Tomassetti and Venerino Poletti

    Citation: Multidisciplinary Respiratory Medicine 2019 14:3

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  11. Content type: Original research article

    The Swiss COPD cohort was established in 2006 to collect data in a primary care setting. The objective of this study was to evaluate possible predictive factors for exacerbation and re-exacerbation.

    Authors: Pascal Urwyler, Nebal Abu Hussein, Pierre O. Bridevaux, Prashant N. Chhajed, Thomas Geiser, Peter Grendelmeier, Ladina Joos Zellweger, Malcolm Kohler, Sabrina Maier, David Miedinger, Michael Tamm, Robert Thurnheer, Thomas Dieterle and Joerg D. Leuppi

    Citation: Multidisciplinary Respiratory Medicine 2019 14:7

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  12. Content type: Original research article

    The analysis of microbiome in respiratory samples is a topic of great interest in chronic respiratory diseases. The method used to prepare sputum samples for microbiome analysis is very heterogeneous. The sele...

    Authors: Martina Oriano, Leonardo Terranova, Antonio Teri, Samantha Sottotetti, Luca Ruggiero, Camilla Tafuro, Paola Marchisio, Andrea Gramegna, Francesco Amati, Fabrizio Nava, Elisa Franceschi, Lisa Cariani, Francesco Blasi and Stefano Aliberti

    Citation: Multidisciplinary Respiratory Medicine 2019 14:6

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  13. Content type: Case report

    Non-invasive ventilation (NIV) is the treatment of choice for patients symptomatic for respiratory muscle dysfunction. It can normalize gas exchange and provide up to continuous non-invasive ventilator support...

    Authors: Paolo I. Banfi, Eleonora Volpato and John R. Bach

    Citation: Multidisciplinary Respiratory Medicine 2019 14:4

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  14. Content type: Original research article

    Poor indoor air quality is a great problem in schools due to a high number of students per classroom, insufficient outside air supply, poor construction and maintenance of school buildings. Bacteria in the ind...

    Authors: Zewudu Andualem, Zemichael Gizaw, Laekemariam Bogale and Henok Dagne

    Citation: Multidisciplinary Respiratory Medicine 2019 14:2

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  15. Content type: Original research article

    Some previous works have tested LUS use in diagnosing and monitoring interstitial lung diseases. B-lines are main sonographic signs for interstitial diseases. Increasing evidences suggest that dyspnea and impa...

    Authors: Andrea Boccatonda, Valentina Decorato, Giulio Cocco, Stefano Marinari and Cosima Schiavone

    Citation: Multidisciplinary Respiratory Medicine 2018 14:1

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  16. Content type: Review

    Obstructive Sleep Apnoea (OSA) is a common sleep disorder that is associated with daytime symptoms and a range of comorbidity and mortality. Continuous Positive Airway Pressure (CPAP) therapy is highly efficac...

    Authors: Kate Sutherland, Kristina Kairaitis, Brendon J. Yee and Peter A. Cistulli

    Citation: Multidisciplinary Respiratory Medicine 2018 13:44

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  17. Content type: Original research article

    The assessment of Idiopathic Pulmonary Fibrosis (IPF) using HRCT requires great experience and is limited by a significant inter-observer variability, even between trained radiologists. The evaluation of HRCT ...

    Authors: Sebastiano Emanuele Torrisi, Stefano Palmucci, Alessandro Stefano, Giorgio Russo, Alfredo Gaetano Torcitto, Daniele Falsaperla, Mauro Gioè, Mauro Pavone, Ada Vancheri, Gianluca Sambataro, Domenico Sambataro, Letizia Antonella Mauro, Emanuele Grassedonio, Antonio Basile and Carlo Vancheri

    Citation: Multidisciplinary Respiratory Medicine 2018 13:43

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  18. Content type: Original research article

    Since 2013 StopTB Italia Onlus supports the Senegalese National Tuberculosis Programme by improving diagnostic capability with technological interventions, ameliorating educational programs for health care per...

    Authors: Mama Moussa Diaw, Mamoudou Ndiaye, Niccolò Riccardi, Riccardo Ungaro, Riccardo Alagna, Daniela Maria Cirillo, Luigi Codecasa, Claudio Viscoli, Laura Ambra Nicolini and Giorgio Besozzi

    Citation: Multidisciplinary Respiratory Medicine 2018 13:41

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  19. Content type: Review

    Fifteen years after its licensure, this revision assesses the role of cefditoren facing the current pharmacoepidemiology of resistances in respiratory human-adapted pathogens (Streptococcus pneumoniae, Streptococ...

    Authors: María-José Giménez, Lorenzo Aguilar and Juan José Granizo

    Citation: Multidisciplinary Respiratory Medicine 2018 13:40

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  20. Content type: Original research article

    Chronic obstructive pulmonary disease (COPD) is associated with high clinical and economic burden. Optimal pharmacological therapy for COPD aims to reduce symptoms and the frequency and severity of exacerbatio...

    Authors: Ami R. Buikema, Lee Brekke, Amy Anderson, Eleena Koep, Damon Van Voorhis, Lucie Sharpsten, Beth Hahn, Riju Ray and Richard H. Stanford

    Citation: Multidisciplinary Respiratory Medicine 2018 13:38

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  21. Content type: Commentary

    The European Respiratory Society recently published an important statement reviewing available evidence on diagnosis and treatment of lung disease associated to alpha-1 antitrypsin deficiency (AATD). Several i...

    Authors: Andrea Gramegna, Stefano Aliberti, Marco Confalonieri, Angelo Corsico, Luca Richeldi, Carlo Vancheri and Francesco Blasi

    Citation: Multidisciplinary Respiratory Medicine 2018 13:39

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  22. Content type: Original research article

    No studies have addressed the impact of lung cancer (LC) on prognosis of patients with idiopathic pulmonary fibrosis (IPF) in Upper Egypt. We aimed to evaluate the prevalence and risk factors for LC among IPF ...

    Authors: Sherif Mohamed, Hassan Bayoumi, Nashwa Abd El-Aziz, Ehab Mousa and Yasser Gamal

    Citation: Multidisciplinary Respiratory Medicine 2018 13:37

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  23. Content type: Review

    Patients with chronic obstructive pulmonary disease (COPD) may experience an acute worsening of respiratory symptoms that results in additional therapy; this event is defined as a COPD exacerbation (AECOPD). H...

    Authors: Ernesto Crisafulli, Enric Barbeta, Antonella Ielpo and Antoni Torres

    Citation: Multidisciplinary Respiratory Medicine 2018 13:36

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  24. Content type: Short report

    Chronic obstructive pulmonary disease (COPD) is a common comorbidity of heart failure (HF), but remains often undiagnosed, and we aimed to identify symptoms predicting COPD in HF. As part of an observational, ...

    Authors: Sara Roversi, Piera Boschetto, Bianca Beghe’, Michela Schito, Martina Garofalo, Mariarita Stendardo, Valentina Ruggieri, Roberto Tonelli, Alessandro Fucili, Roberto D’Amico, Federico Banchelli, Leonardo M. Fabbri and Enrico M. Clini

    Citation: Multidisciplinary Respiratory Medicine 2018 13:35

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  25. Content type: Review

    Tracheal surgery requires a highly specialized team of anesthesiologists, thoracic surgeons, and operative support staff. It remain a formidable challenge for surgeons due to the criticality connected to anato...

    Authors: Alessandra Siciliani, Erino Angelo Rendina and Mohsen Ibrahim

    Citation: Multidisciplinary Respiratory Medicine 2018 13:34

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  26. Content type: Case report

    Hemoptysis is a frequent sign of respiratory and non-respiratory diseases. While in most cases the underlying cause is rapidly identified, sometimes the real etiology might be misdiagnosed with dramatic delay ...

    Authors: Matteo Fontana, Roberto Tonelli, Filippo Gozzi, Ivana Castaniere, Alessandro Marchioni, Riccardo Fantini, Francesca Coppi, Filippo Natali, Elisabetta Rovatti and Enrico Clini

    Citation: Multidisciplinary Respiratory Medicine 2018 13:25

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  27. Content type: Case report

    Acute respiratory failure can be triggered by several causes, either of pulmonary or extra-pulmonary origin. Pompe disease, or type II glycogen storage disease, is a serious and often fatal disorder, due to a ...

    Authors: Francesco Menzella, Luca Codeluppi, Mirco Lusuardi, Carla Galeone, Franco Valzania and Nicola Facciolongo

    Citation: Multidisciplinary Respiratory Medicine 2018 13:32

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  28. Content type: Original Research Article

    A substantial increase in pulmonary and extra-pulmonary diseases due to non-tuberculous mycobacteria (NTM) has been documented worldwide, especially among subjects suffering from chronic respiratory diseases a...

    Authors: Stefano Aliberti, Luigi Ruffo Codecasa, Andrea Gori, Giovanni Sotgiu, Maura Spotti, Antonio Di Biagio, Andrea Calcagno, Stefano Nardini, Baroukh Maurice Assael, Enrico Tortoli, Giorgio Besozzi, Maurizio Ferrarese, Alberto Matteelli, Enrico Girardi, Saverio De Lorenzo, Manuela Seia…

    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):33

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    This article is part of a Supplement: Volume 13 Supplement 1

  29. Content type: Short Report

    Determining the effects of antimicrobial therapies on airway microbiology at a population-level is essential. Such analysis allows, for example, surveillance of antibiotic-induced changes in pathogen prevalenc...

    Authors: Steven L. Taylor, Lex E. X. Leong, Fredrick M. Mobegi, Jocelyn M. Choo, Lucy D. Burr, Steve Wesselingh and Geraint B. Rogers

    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):30

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    This article is part of a Supplement: Volume 13 Supplement 1

  30. Content type: Review

    Bronchiectasis is the final result of different processes and most of the guidelines advocate for a careful evaluation of those etiologies which might be treated or might change patients’ management, including...

    Authors: Andrea Gramegna, Stefano Aliberti, Manuela Seia, Luigi Porcaro, Vera Bianchi, Carlo Castellani, Paola Melotti, Claudio Sorio, Enza Consalvo, Elisa Franceschi, Francesco Amati, Martina Contarini, Michele Gaffuri, Luca Roncoroni, Barbara Vigone, Angela Bellofiore…

    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):29

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    This article is part of a Supplement: Volume 13 Supplement 1

  31. Content type: Review

    Bronchiectasis represents the final pathway of several infectious, genetic, immunologic or allergic disorders. Accurate and prompt identification of the underlying cause is a key recommendation of several inte...

    Authors: Martina Contarini, Amelia Shoemark, Jessica Rademacher, Simon Finch, Andrea Gramegna, Michele Gaffuri, Luca Roncoroni, Manuela Seia, Felix C. Ringshausen, Tobias Welte, Francesco Blasi, Stefano Aliberti and James D. Chalmers

    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):26

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    This article is part of a Supplement: Volume 13 Supplement 1

  32. Content type: Short Report

    The contemporary diagnosis of bronchiectasis requires CT scanning to describe specific structural lung changes. Scoring systems have been designed and validated in some specific causes of bronchiectasis to all...

    Authors: Philip Robinson and Lucy Morgan

    Citation: Multidisciplinary Respiratory Medicine 2018 13(Suppl 1):24

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    This article is part of a Supplement: Volume 13 Supplement 1

  33. Content type: Case report

    Double aortic arch is a rare congenital and complete vascular ring around trachea and esophagus. It is usually diagnosed during infancy. The symptoms are generally related to respiratory and gastroesophageal t...

    Authors: Davide Piloni, Claudio Tirelli, Rita Di Domenica, Valentina Conio, Amelia Grosso, Vanessa Ronzoni, Filippo Antonacci, Pasquale Totaro and Angelo G. Corsico

    Citation: Multidisciplinary Respiratory Medicine 2018 13:21

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  34. Content type: Original research article

    Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis, mainly associated with work or environmental exposure to asbestos. MPM’s molecular profile is largerly unexplored and effective ...

    Authors: Matteo Bosio, Elena Salvaterra, Francesca Datturi, Patrizia Morbini, Michele Zorzetto, Simona Inghilleri, Stefano Tomaselli, Patrizia Mangiarotti, Federica Meloni, Isa Cerveri and Giulia Maria Stella

    Citation: Multidisciplinary Respiratory Medicine 2018 13:27

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  35. Content type: Original Research Article

    Understanding positive and negative influences on adult immunization status can help healthcare providers to better identify and target patients who are likely to need immunization. Our aim was to assess and c...

    Authors: Stephanie Attard Camilleri, Juanita Camilleri Casingena, Kentaro Yamagata and Martin Balzan

    Citation: Multidisciplinary Respiratory Medicine 2018 13:23

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  36. Content type: Correction

    After publication of the Original research article [1] it was brought to our attention that the sentence at pag 6 (between Figure 3 and Figure 4)) must be corrected as follows: “The mean duration of inactivity...

    Authors: Roberto W. Dal Negro, Luca Bonadiman and Paola Turco

    Citation: Multidisciplinary Respiratory Medicine 2018 13:31

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    The original article was published in Multidisciplinary Respiratory Medicine 2018 13:18

  37. Content type: Original research article

    Despite advances with regard to “do not attempt resuscitation order”, physicians are still reluctant to implement it. In fact, while the nurses could be of great help in making decision about “do not attempt r...

    Authors: Masoud Fallahi, Somaye Mahdavikian, Alireza Abdi, Fariba Borhani, Parvin Taghizadeh and Behzad Hematpoor

    Citation: Multidisciplinary Respiratory Medicine 2018 13:20

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  38. Content type: Meeting report

    This paper summarizes the presentations submitted for publication of the 12th AIST National Congress (Associazione Italiana Studio Tosse/Italian Association for Cough Study) entitled “The thousand facets of cough...

    Authors: Alessandro Zanasi, Antonio M. Morselli-Labate, Massimiliano Mazzolini, Marianna Mastroroberto, Roberto W. Dal Negro, Ivan Poliacek, Alyn H. Morice, Sara Maio, Giovanni Viegi, Jamie Koufman, Francesco Torresan, Alexandros Ioannou, Daniele Mandolesi, Elisa Liverani, Amedeo Montale, Franco Bazzoli…

    Citation: Multidisciplinary Respiratory Medicine 2018 13:17

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  39. Content type: Original research article

    Bronchial asthma is an inflammatory disease of the airways. Beclomethasone dipropionate/Formoterol (BDP/F) and Fluticasone furoate/Vilanterol (FF/V) are two of the most effective LABA/ICS combinations for mana...

    Authors: Roberto W. Dal Negro, Luca Bonadiman and Paola Turco

    Citation: Multidisciplinary Respiratory Medicine 2018 13:18

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    The Correction to this article has been published in Multidisciplinary Respiratory Medicine 2018 13:31

  40. Content type: Case report

    Recently, it is reported that Actinomyces meyeri is the most common species causing actinomycosis. However, to our knowledge, there was no report about pulmonary actinomycosis attributable to A. meyeri presenting...

    Authors: Saori Nishizawa, Keisuke Anan, Kazunori Tobino, Masanobu Okahisa, Yuki Goto, Kojin Murakami, Takuto Sueyasu, Miyuki Munechika, Kohei Yoshimine and Mai Yoshino

    Citation: Multidisciplinary Respiratory Medicine 2018 13:19

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  41. Content type: Short report

    The drug pirfenidone has been shown to slow the progression and decrease mortality of idiopathic pulmonary fibrosis (IPF). Its exact mechanism is unknown, but it likely inhibits pro-fibrotic cytokine transform...

    Authors: Amber Mortensen, Lauren Cherrier and Rajat Walia

    Citation: Multidisciplinary Respiratory Medicine 2018 13:16

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  42. Content type: Original research article

    Outdoor air pollution is a major threat to global public health that needs responsible participation of researchers at all levels. Assessing research output is an important step in highlighting national and in...

    Authors: Waleed M. Sweileh, Samah W. Al-Jabi, Sa’ed H. Zyoud and Ansam F. Sawalha

    Citation: Multidisciplinary Respiratory Medicine 2018 13:15

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  43. Content type: Original research article

    Idiopathic pulmonary fibrosis (IPF) is characterized by progressive loss of lung function with high mortality within the first 5 years from diagnosis. In 2011–2014, two drugs, pirfenidone and nintedanib, have ...

    Authors: Ida Pesonen, Lisa Carlson, Nicola Murgia, Riitta Kaarteenaho, Carl Magnus Sköld, Marjukka Myllärniemi and Giovanni Ferrara

    Citation: Multidisciplinary Respiratory Medicine 2018 13:14

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  44. Content type: Short report

    Medical air (MA) is widely used in hospitals, often manufactured onsite by compressing external ambient air and supplied through a local network piping system. Onsite production gives rise to a risk of impurit...

    Authors: Paul Edwards, Patricia-Ann Therriault and Ira Katz

    Citation: Multidisciplinary Respiratory Medicine 2018 13:12

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