Figure 4

Chronic alcohol consumption increases tnf production by airway Mφ _s . Definition of abbreviations: BALF, bronchoalveolar lavage fluid; Mφ macrophage; PGN, peptidoglycan; TNF, tumor necrosis factor. Mice (6 mice per group) were treated with alcohol or saline and challenged with PGN as described in Figure 1. BALF and Mφs were prepared as described in the text. Total proteins were extracted from purified Mφs and the levels of TNF determined by ELISA. The annotations are the same as in Figures 1-3.