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Table 2 Factors associated with health-related quality of life, according dimensions of EuroQol-5D questionnaire (n = 2,125)

From: Factors associated with health-related quality of life in adults with asthma. A cross-sectional study

A

% patients without problems

Mobility Adjusted OR (95%CI)*

Gender

Female

883/1,227 (72.0%)

1

Male

726/898 (80.8%)

1.49 (1.13,1.97)

Age

≥ 60 years

335/638 (52.5%)

1

40 to 59 years

551/704 (78.3%)

1.96 (1.41,2.73)

18 to 39 years

723/783 (92.3%)

4.13 (2.71,6.32)

BMI (Kg/m 2 )

≥ 30

243/424 (57.3%)

1

≥ 25 to 30

656/873 (75.1%)

1.64 (1.20,2.23)

< 25

709/826 (85.8%)

2.14 (1.50,3.04)

Educational level

None

74/170 (43.5%)

1

Primary

613/900 (68.1%)

1.46 (0.97,2.20)

Secondary

600/706 (85.0%)

1.77 (1.10,2.85)

University

319/345 (92.5%)

3.19 (1.73,5.88)

Occupation

Non active worker

648/1,029 (63.0%)

1

Active worker

960/1,094 (87.7%)

1.43 (1.04,1.97)

Living status

Lives alone

145/237 (61.2%)

1

Lives with someone

1,461/1,885 (77.5%)

1.60 (1.10,2.33)

ACQ score

>1.50

437/792 (55.2%)

1

0.75-1.50

464/561 (82.7%)

2.68 (1.96,3.66)

<0.75

708/772 (91.7%)

4.83 (3.37,6.92)

Hospital admissions

Yes

54/179 (30.2%)

1

No

1,555/1,946 (79.9%)

2.64 (1.71,4.07)

B

% patients without problems

Self-care Adjusted OR (95%CI)*

Age

≥ 60 years

335/638 (52.5%)

1

40 to 59 years

551/704 (78.3%)

2.25 (1.34,3.75)

18 to 39 years

723/783 (92.3%)

4.30 (1.93,9.54)

Educational level

None

74/170 (43.5%)

1

Primary

613/900 (68.1%)

3.08 (1.89,5.03)

Secondary

600/706 (85.0%)

2.71 (1.40,5.24)

University

319/345 (92.5%)

3.21 (1.20,8.54)

Occupation

Non active worker

648/1,029 (63.0%)

1

Active worker

960/1,094 (87.7%)

2.77 (1.52,5.04)

Living status

Lives alone

145/237 (61.2%)

1

Lives with someone

1,461/1,885 (77.5%)

1.70 (1.03,2.80)

Asthma severity

Severe persistent

28/90 (31.1%)

1

Moderate persistent

449/706 (63.6%)

1.81 (0.98,3.34)

Mild persistent

655/774 (84.6%)

3.32 (1.61,6.85)

Intermittent

476/554 (85.9%)

3.21 (1.38,7.46)

Stressful event last 15 days

Yes

207/307 (67.4%)

1

No

1,394/1,810 (77.0%)

1.99 (1.22,3.26)

Asthma treatment

Oral corticosteroids

62/158 (39.2%)

1

LABA + IC

1,114/1,476 (75.5%)

1.34 (0.77,2.32)

Inhaled corticosteroids

180/209 (86.1%)

4.07 (1.07,15.48)

SABA or LABA

230/255 (90.2%)

1.76 (0.58,5.33)

ACQ score

>1.50

437/792 (55.2%)

1

0.75-1.50

464/561 (82.7%)

2.49 (1.43,4.36)

<0.75

708/772 (91.7%)

2.69 (1.41,5.14)

Hospital admissions

Yes

54/179 (30.2%)

1

No

1,555/1,946 (79.9%)

2.52 (1.52,4.17)

C

% patients without problems

Usual activities Adjusted OR (95%CI)*

Age

≥ 60 years

335/638 (52.5%)

1

40 to 59 years

551/704 (78.3%)

2.27 (1.63,3.16)

18 to 39 years

723/783 (92.3%)

2.67 (1.80,3.95)

BMI (Kg/m 2 )

≥ 30

243/424 (57.3%)

1

≥ 25 to 30

656/873 (75.1%)

1.27 (0.93,1.73)

< 25

709/826 (85.8%)

1.43 (1.02,2.02)

Educational level

None

74/170 (43.5%)

1

Primary

613/900 (68.1%)

1.51 (0.99,2.31)

Secondary

600/706 (85.0%)

1.86 (1.16,2.99)

University

319/345 (92.5%)

2.62 (1.49,4.60)

Living status

Lives alone

145/237 (61.2%)

1

Lives with someone

1,461/1,885 (77.5%)

1.76 (1.23,2.53)

Asthma severity

Severe persistent

28/90 (31.1%)

1

Moderate persistent

449/706 (63.6%)

1.75 (0.95,3.24)

Mild persistent

655/774 (84.6%)

1.97 (1.04,3.74)

Intermittent

476/554 (85.9%)

1.76 (0.90,3.45)

Asthma treatment

Oral corticosteroids

62/158 (39.2%)

1

LABA + IC

1,114/1,476 (75.5%)

1.41 (0.88,2.23)

Inhaled corticosteroids

180/209 (86.1%)

2.43 (1.27,4.62)

SABA or LABA

230/255 (90.2%)

1.97 (1.05,3.71)

ACQ score

>1.50

437/792 (55.2%)

1

0.75-1.50

464/561 (82.7%)

3.74 (2.79,5.09)

<0.75

708/772 (91.7%)

7.48 (5.29,10.58)

Hospital admissions

Yes

54/179 (30.2%)

1

No

1,555/1,946 (79.9%)

1.75 (1.14,2.68)

Emergency visits

Yes

503/810 (62.1%)

1

No

1,106/1,315 (84.1%)

1.67 (1.28,2.17)

D

% patients without problems

Pain/Discomfort Adjusted OR (95%CI)*

Gender

Female

883/1,227 (72.0%)

1

Male

726/898 (80.8%)

1.55 (1.17,2.06)

Age

≥ 60 years

335/638 (52.5%)

1

40 to 59 years

551/704 (78.3%)

2.32 (1.68,3.22)

18 to 39 years

723/783 (92.3%)

5.27 (3.52,7.88)

BMI (Kg/m 2 )

≥ 30

243/424 (57.3%)

1

≥ 25 to 30

656/873 (75.1%)

1.36 (1.00,1.85)

< 25

709/826 (85.8%)

1.75 (1.25,2.47)

Educational level

None

74/170 (43.5%)

1

Primary

613/900 (68.1%)

1.59 (1.02,2.49)

Secondary

600/706 (85.0%)

1.88 (1.14,3.09)

University

319/345 (92.5%)

2.23 (1.25,3.99)

Occupation

Non active worker

648/1029 (63.0%)

1

Active worker

960/1094 (87.7%)

1.43 (1.06,1.93)

Asthma severity

Severe persistent

28/90 (31.1%)

1

Moderate persistent

449/706 (63.6%)

2.24 (1.14,4.41)

Mild persistent

655/774 (84.6%)

3.35 (1.66,6.75)

Intermittent

476/554 (85.9%)

2.65 (1.28,5.48)

Stressful event last 15 days

Yes

207/307 (67.4%)

1

No

1,394/1,810 (77.0%)

2.04 (1.46,2.83)

ACQ score

>1.50

437/792 (55.2%)

1

0.75-1.50

464/561 (82.7%)

1.80 (1.33,2.44)

<0.75

708/772 (91.7%)

2.78 (1.99,3.88)

Hospital admissions

Yes

54/179 (30.2%)

1

No

1,555/1,946 (79.9%)

2.05 (1.30,3.25)

Emergency visits

Yes

503/810 (62.1%)

1

No

1,106/1,315 (84.1%)

1.37 (1.03,1.81)

E

% patients without problems

Anxiety/Depression Adjusted OR (95%CI)*

Gender

Female

883/1,227 (72.0%)

1

Male

726/898 (80.8%)

1.84 (1.41,2.41)

Age

≥ 60 years

335/638 (52.5%)

1

40 to 59 years

551/704 (78.3%)

1.35 (0.98,1.87)

18 to 39 years

723/783 (92.3%)

2.37 (1.62,3.47)

Educational level

None

74/170 (43.5%)

1

Primary

613/900 (68.1%)

2.04 (1.33,3.12)

Secondary

600/706 (85.0%)

2.18 (1.36,3.49)

University

319/345 (92.5%)

2.55 (1.49,4.37)

Place of residence

Rural

632/859 (73.6%)

1

Urban

977/1265 (77.2%)

1.28 (1.01,1.62)

Asthma severity

Severe persistent

28/90 (31.1%)

1

Moderate persistent

449/706 (63.6%)

1.74 (0.96,3.15)

Mild persistent

655/774 (84.6%)

2.61 (1.40,4.87)

Intermittent

476/554 (85.9%)

2.27 (1.19,4.33)

Stressful event last 15 days

Yes

207/307 (67.4%)

1

No

1,394/1,810 (77.0%)

5.57 (4.08,7.59)

ACQ score

>1.50

437/792 (55.2%)

1

0.75-1.50

464/561 (82.7%)

1.36 (1.01,1.83)

<0.75

708/772 (91.7%)

1.66 (1.21,2.28)

Hospital admissions

Yes

54/179 (30.2%)

1

No

1,555/1,946 (79.9%)

2.09 (1.36,3.22)

Emergency visits

Yes

503/810 (62.1%)

1

No

1,106/1,315 (84.1%)

1.32 (1.02,1.72)

  1. *Adjusted Odds Ratio (Adjusted by all the variables in the Table 1).
  2. NS, Crude Odds Ratio non significant; BMI, Body mass index; SABA, Short- acting beta2 agonists; LABA, Long-acting beta2 agonists; SD, Standard Deviation; IC, Inhaled corticosteroids.