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Table 1 Demographic data, pulmonary function test and SF-36 results of the study population

From: Effect of thyroid function on COPD exacerbation frequency: a preliminary study

PARAMETERS

COPD + Hypothyroidism

COPD

CONTROL

P

Group 1

Group 2

Group 3

(n = 44)

(n = 44)

(n = 40)

Age (years)

64.1 ± 7.1

66.5 ± 6

64.7 ± 3.4

0.26

Gender (F/M)

22/22

22/22

20/20

1

Height (cm)

162.7 ± 7.2

166.2 ± 7.3

167 ± 8.4

0.11

Weight (kg)

78.7 ± 15.8

76.1 ± 17.1

78.5 ± 12.2

0.9

BMI (kg/m2)

29.73 ± 5.74

27.43 ± 5.35

27.88 ± 3.98

0.296

Cigarette pack/year

37.6 ± 22.6a,b

54.2 ± 26.7a,c

0bc

<0.0001

FEV1/FVC

67.2 ± 11.1a,b

53.2 ± 15.6a,c

79.5 ± 5.2b,c

<0.0001

FEV1(L)

2.1 ± 0.7a

2.01 ± 0.53b

3.6 ± 0.58 a,b

<0.0001

FEV1(%)

83.1 ± 22.2a

77.5 ± 16.2b

116.9 ± 17.5 a,b

<0.0001

FVC (L)

3.1 ± 0.9a,b

3.67 ± 0.9a,c

4.6 ± 0.8 b,c

<0.0001

FVC (%)

100.1 ± 19.2a

108.9 ± 21b

121.8 ± 19.6 a,b

0.003

FEF25–75 (%)

47.5 ± 27.4a,b

29.6 ± 12.3a,c

95.1 ± 21.9 b,c

<0.0001

TLC (%)

107.2 ± 19.5

105.3 ± 19

113.9 ± 15.9

0.22

TLC (L)

5.9 ± 1.4

6.5 ± 1.5

6.55 ± 1.03

0.32

MIP (cmH2O)

69.6 ± 30.7

67.3 ± 17.5

74.05 ± 24.3

0.673

MEP (cmH2O)

25.6 ± 9.1a,b

34.9 ± 11.5a,c

26.7 ± 6.4b,c

0.004

General health

35 (0–80)a

45 (10–70)b

69.5 (40–82)a,b

<0.0001

Physical functioning

52.5 (0–100) a

62.5 (25–95) b

90 (50–100) a,b

<0.0001

Physical Role limitation

25 (0–100) a

25 (0–100) b

100(50–100)a,b

<0.0001

Emotional Role limitation

33 (0–100) a

33 (0–100) b

66.6(0–100) a,b

<0.0001

Social functioning

50 (13–100) a

56 (0–100) b

87.5(38100)a,b

<0.0001

Pain

60 (0–100) a

85 (20–100) b

100(40–100)a,b

0.029

Vitality

52.5 (10–85) a

57.5 (20–92) b

80.5(45100)a,b

0.001

Mental health

52.5 (12–80) a

58 (15–90) b

72 (50–95) a,b

<0.0001

  1. Data are expressed as mean ± SD for parameters with normal distribution and median for parameters with skewed distribution (range min-max).
  2. Where P is significant, values within a row with the same superscript letter are significantly different.
  3. BMI, Body mass index; COPD, Chronic obstructive pulmonary disease; F/M, Female/Male; FEF25–75%, Forced expiratory flow at 25–75%; FEV1, Forced expiratory volume at 1 second; FVC, Forced vital capacity; MEP, Maximal expiratory pressure; MIP, Maximal inspiratory pressure; SF-36, Short form-36; TLC, Total lung capacity.