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Table 3 Pulmonary function test results in healthy volunteers and acromegalic patients (% predicted values)

From: Pulmonary function testing and chest tomography in patients with acromegaly

  Control group (n = 20) Acromegaly group (n = 20) p
FVC (% predicted) 98.9 ± 21.4 107.1 ± 15.9 0.028
FEV1 (% predicted) 96.2 ± 11.9 104.8 ± 15.5 0.057
FEV1/FVC (% predicted) 97.2 ± 3.30 94.0 ± 4.86 0.572
FEF25-75% (% predicted) 91.5 ± 18.9 105.9 ± 20.1 0.261
FEF25-75%/FVC (% predicted) 95.2 ± 6.77 99.4 ± 7.05 0.630
MIP (% predicted) 85.3 ± 24.1 71.4 ± 27.8 0.005
MEP (% predicted) 103.7 ± 19.2 55.9 ± 17.1 <0.001
TLC (% predicted) 93.7 ± 7.60 107.3 ± 12.9 0.002
RV (% predicted) 90.0 ± 14.6 114.1 ± 22.7 <0.001
RV/TLC (% predicted) 94.9 ± 13.4 107.1 ± 27.2 0.068
DLCO (% predicted) 103.1 ± 13.9 103.7 ± 24.4 0.968
VA (% predicted) 90.5 ± 15.5 93.6 ± 12.2 0.147
DLCO/VA (% predicted) 116.4 ± 22.3 110.2 ± 18.5 0.346
  1. Values are means ± SD or numbers (%). DLCO, diffusing capacity for carbon monoxide, FEF25-75%, forced expiratory flow during the middle half of the FVC; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; Raw, airway resistance; RV, residual volume; TLC, total lung capacity; VA, alveolar volume.