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Table 3 Pulmonary function test results in healthy volunteers and acromegalic patients (% predicted values)

From: Pulmonary function testing and chest tomography in patients with acromegaly

 

Control group (n = 20)

Acromegaly group (n = 20)

p

FVC (% predicted)

98.9 ± 21.4

107.1 ± 15.9

0.028

FEV1 (% predicted)

96.2 ± 11.9

104.8 ± 15.5

0.057

FEV1/FVC (% predicted)

97.2 ± 3.30

94.0 ± 4.86

0.572

FEF25-75% (% predicted)

91.5 ± 18.9

105.9 ± 20.1

0.261

FEF25-75%/FVC (% predicted)

95.2 ± 6.77

99.4 ± 7.05

0.630

MIP (% predicted)

85.3 ± 24.1

71.4 ± 27.8

0.005

MEP (% predicted)

103.7 ± 19.2

55.9 ± 17.1

<0.001

TLC (% predicted)

93.7 ± 7.60

107.3 ± 12.9

0.002

RV (% predicted)

90.0 ± 14.6

114.1 ± 22.7

<0.001

RV/TLC (% predicted)

94.9 ± 13.4

107.1 ± 27.2

0.068

DLCO (% predicted)

103.1 ± 13.9

103.7 ± 24.4

0.968

VA (% predicted)

90.5 ± 15.5

93.6 ± 12.2

0.147

DLCO/VA (% predicted)

116.4 ± 22.3

110.2 ± 18.5

0.346

  1. Values are means ± SD or numbers (%). DLCO, diffusing capacity for carbon monoxide, FEF25-75%, forced expiratory flow during the middle half of the FVC; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; Raw, airway resistance; RV, residual volume; TLC, total lung capacity; VA, alveolar volume.