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Table 1 Pleural adenosine deaminase and interferon-γ levels in patients with tuberculosis, malignancy and non-tuberculosis non-malignancy in the study group

From: Diagnostic utility of serum and pleural levels of adenosine deaminase 1–2, and interferon-γ in the diagnosis of pleural tuberculosis

  Group 1 (Tuberculosis) (n = 43) Group 2 (Malignancy) (n = 23) Group 3 (Non-tuberculosis non-malignancy) (n = 27) p
Age (yrs) 26 (20–35) 62 (49–75) 67 (44–75) 0.0001 P (1–2) = 0.0001
P (1–3) = 0.0001
P (2–3) = 0.907
Male/female 30/13 12/11 21/6 0.144
Pleural ADA-1 (U/L) 21.06 (14.55-33.56) 7.48 (5.61-17.16) 14.89 (7.39-21.06) 0.0001 P (1–2) = 0.0001
P (1–3) = 0.008
P (2–3) = 0.067
Pleural ADA-2 (U/L) 38.00 (29.66-53.15) 8.86 (6.40-12.60) 11.32 (5.80-15.23) 0.0001 P (1–2) = 0.0001
P(1–3) = 0.0001
P(2–3) = 0.402
Pleural total ADA (U/L) 60.04 (44.66-87.60) 19.78 (16.02-24.43) 23.92 (16.36-40.11) 0.0001 P (1–2) = 0.0001
P (1–3) = 0.0001
P (2–3) = 0.170
Pleural μg/ml (pg/ml) 185.00 (105.00-460.00) 55.00 (15.00-110.00) 75.00 (36.00-195.00) 0.0001 P (1–2) = 0.0001
P (1–3) = 0.006
P (2–3) = 0.110
  1. ADA, Adenosine deaminase; IFN-γ, Interferon gamma.
  2. Data are expressed as median (interquartile range).